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White blood cell count, inflammation linked to cancer deaths

the observed association between WBC count and cancer mortality is not fully explained by smoking."

The study also suggests that aspirin may have a greater protective effect against cancer for those with high WBC, as the risk of cancer death was higher among those with high WBC who did not take aspirin weekly than among those who did.

"These data provide important new epidemiological evidence of an essential link between inflammation and cancer mortality," the authors write. "Our findings suggest that local inflammatory processes that have long been known to be associated with tumor progression may be reflected in the systemic inflammatory marker of higher WBC count."


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Contact: Anoop Shankar, M.D., Ph.D.
ashankar@nus.edu.sg
JAMA and Archives Journals
23-Jan-2006


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