Women report various symptoms after stopping hormo...( inicians would agree with the American ...),Health

inicians would agree with the American College of Obstetricians and Gynecologists that when symptoms of menopause necessitate hormone therapy, treatment should be prescribed at the lowest effective dose for the shortest possible time. The high frequency of symptoms reported by the WHI participants may be a result of the abrupt withdrawal from hormone (or placebo) therapy. Thus, when it is time to consider discontinuing hormone therapy, gradual tapering of the dose would be a logical clinical strategy arising from these new observations from the WHI."

"As has been the experience with prior reports from the WHI, these latest results bring some surprises, some answers to important clinical concerns, and some new questions for future investigation," Dr. Petitti concludes.

(JAMA. 2005;294:245246. Available pre-embargo to the media at www.jamamedia.org.)

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Contact: Alison Duffy
508-856-2000
JAMA and Archives Journals
12-Jul-2005

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