Worldwide study looks to find causes of type ...( ve are responsible for the increasing i...),Health

ve are responsible for the increasing incidence of the disease, are still elusive. "There are many suspects like cow's milk, like coxsackie viral infection (cause of the common, painful and blistering hand, foot and mouth disease) that have been suggested as triggers for type 1 diabetes. But the literature is very controversial: some studies are for it, some are against it," says Dr. She.

That's why TEDDY The Environmental Determinants of Diabetes in the Young was born.

The study includes newborns in four states and three countries. MCG is the lead site for seven hospitals, including MCG Medical Center, University Hospital and St. Joseph Hospital in Augusta; Northside Hospital in Atlanta; and three hospitals in Gainesville, Fla. Additional lead sites include Barbara Davis Center at the University of Colorado; Pacific Northwest Research Institute in Seattle; the University of Turku in Finland; Lund University in Sweden; and the Diabetes Research Institute in Munich, Germany. Moffitt Cancer Center and Research Institute at the University of South Florida is analyzing the extensive data collected by study sites as they enroll participants over the next four years.

TEDDY is similar to another screening study driven by Dr. She called PANDA Prospective Assessment in Newborns for Diabetes Autoimmunity which also uses a drop of blood taken from the umbilical cord or the traditional heel prick to screen newborns for high-risk genes. PANDA will follow those with the genes for five years.

While that study continues, the more expansive study that is following so many aspects of these children's lives is now getting priority when it comes to enrolling newborns, says Diane Hopkins, study coordinator for the Center for Biotechnology and Genomic Medicine and multi-site research manager for TEDDY in Georgia and Florida.

"The families make a real commitment to this research," she says. "We are asking them to record every time the chi
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Contact: Toni Baker
tbaker@mcg.edu
706-721-4421
Medical College of Georgia
13-Feb-2006

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