New study shows hope for treating inhalant abuse
...f Synapse, available online September 30. Inhalant abuse or "huffing" continues to grow as a serious health...tly, our results show promise in treating inhalant abuse as it continues to grow as a problem among adolescents." There are currently no pharmaceutical treat...A liking for sweets, combined with novelty seeking, may predict alcoholism
..., higher lifetime rates of heavy drinking, alcohol abuse and dependence. In the past, there were several attempts to use novelty seeking as a predictor of alcoholism that failed because elevated novelty seeking can be also found in individuals who do not have any substance-abuse problems. It has been know...Genetically-engineered 'marathon mouse' keeps on running
... that such drugs would also have the potential for abuse among athletes, who could take them to enhance performance. Further studies, said Evans, will aim at understanding the effects of PPAR-delta-enhancing drugs on the performance of normal animals. The researchers also plan to explore how such treatmen...Infant rats eagerly accept high concentrations of alcohol upon first exposure
...believed to enhance the risk of alcohol use and/or abuse later in life. Research shows that infant rats ar...believed to enhance the risk of alcohol use and/or abuse later in life. A study in the August issue of Alcoholism: Clinical & Experimental Research examin...Vollum scientists find new form of dopamine transmission
...s of the brain associated with movement, substance abuse and mental disorders. Scientists at the Vollum Ins...ntion deficit hyperactivity disorder and substance abuse could help them someday identify new therapeutic targets for these conditions. "We don't know yet wh...OHSU scientists find gene influencing drug withdrawal
... a motivational force that perpetuates drug use or abuse and contributes to relapse," said Nikki Walter, re...ing mechanisms, and contribution to continued drug abuse and relapse are uncovered, new pharmaceutical therapies could be identified, Buck said. "For those p...Antioxidants during pregnancy may help prevent birth defects tied to alcohol
CHAPEL HILL -- Pregnant women who abuse alcohol may reduce the risk of birth defects in th...mber of American adults age 18 years and older who abuse alcohol or are alcohol dependent rose from 13.8 million (7.41 percent) in 1991-1992 to 17.6 million ...JCI table of contents, 15 June 2004
...liver disease, but found in individuals who do not abuse alcohol. Of interest, the researchers were also able to trace the effects here to the increased expression of a gene that is involved in fat cell differentiation, PPAR_amma. In addition to having the hallmarks of nonalcoholic steatohepatitis, by 40 ...Nanotechnology pioneer slays 'grey goo' myths
...from serious safety concerns, such as a deliberate abuse of the technology. Phoenix said: "Runaway replicat...olecular nanotechnology should consider deliberate abuse as a primary concern, and runaway replication as a more distant issue." In 1986, Drexler described a...JCI table of contents, 1 June 2004
...disorder, and it is often misdiagnosed as signs of abuse in young children and as lichen planus in adults. Previous work on lichen sclerosus has shown the presence of specific autoantigens to extracellular matrix protein 1 (ECM1), implicating its potential involvement in the disease. ECM1 is a protein pres...The skinny on diagnosing skin disease
...disorder, and it is often misdiagnosed as signs of abuse in young children and as lichen planus in adults. Previous work on lichen sclerosus has shown the presence of specific autoantigens to extracellular matrix protein 1 (ECM1), implicating its potential involvement in the disease. ECM1 is a protein pres......on Americans suffer from alcohol problems. Alcohol abuse costs the economy roughly $185 billion per year. Other researchers involved in the study were Adip Roy, Huaibo Zhang and Tiejun Xu, postdoctoral research associates in the UIC department of psychiatry. The National Institute on Alcohol Abuse and Alco...... "recovery" of patients' possible childhood sexual abuse has been called into question by a Canadian study. It found that a "staggering" two-out-of-three participants accepted a concocted false grade-school event as having really happened to them when suggestions regarding the event were supplemented with ...Transporter's function provides support for eating vegetables, limiting antibiotics
...d reason to eat your fruits and vegetables and not abuse antibiotics. A transporter in the colon called SLC5A8 plays an important role in enabling the colon to get the last bit of good out of food before the unusable is flushed away, according to research currently published online as an accelerated commu...Drug addiction, learning share common brain protein
...d cocaine exposure, as mice typically do. "Drug abuse is a complex disorder and will therefore be influenced by multiple genes," Caron noted. "PSD-95 represents one cog in the wheel." The brain protein likely plays a role in addiction to other drugs -- including nicotine, alcohol, morphine and heroine ...Proteomics and alcoholism research
...the pathophysiological characterization of alcohol abuse and alcoholism." Scientists announced a new, international initiative to characterize the liver proteome. It will focus on hepatocellular carcinoma, often associated with cirrhosis, which is commonly cause by alcohol consumption. Laura Beretta, one...Studies suggest brain injury results from developmental exposure to alcohol, anesthesia, and lead
...ves and anticonvulsants; some are drugs that women abuse while pregnant. Olney and Susser noted that more work is needed to demonstrate whether lead has the same effect on the developing brain as the substances tested by Olney and his research group. "We're identifying factors that are most likely to caus...Bridging the gap between genetics and motivations to drink alcohol
..." "Although there is much consensus that alcohol abuse and dependence are caused, in part, by genetic fac...unctioning. They also determined lifetime alcohol abuse and/or dependence among the study participants through use of a structured interview that used crite...Researchers find an association between alcohol dependence and the GABAA receptor gene GABRG3
... the neurochemical pathways affecting alcohol use, abuse and dependence. A study in the January issue of Alcoholism: Clinical & Experimental Research , using family-based analyses to examine the role of a cluster of GABAA receptor genes on chromosome 15q, becomes one of the first to demonstrate a consist......holism." Finding that GABA is involved in alcohol abuse and dependence supports a current theory that predisposition to alcoholism might be inherited as part of a general state of brain overactivation. People at risk for alcoholism may inherit a variety of genes that contribute to this state. Perhaps alco...