Fruit Flies May Shed Light On Cocaine Addiction
... scientists unravel the molecular basis of cocaine addiction in people. It may also lay the foundation for highly specific drugs to treat cocaineaddiction. The research, performed by Dr. Jay Hirsh and Colleen McClung of the Universityof Virginia in Charlottesville, grew out of the group's long-term geneticstu...Drunken Fruit Flies Reveal Molecular Pathway Regulating Sensitivity To Alcohol
...of the molecular mechanisms causing drug abuse and addiction inthe near future." The finding, which sheds light on how fruit flies become drunk, aims to addressin the future what makes some people more apt to become alcoholics.Previous studies have determined that people who are less sensitive to alcohol'simpa...Gene Variant Found That Can Help Protect Against Nicotine Addiction
...o do not. They have greater resistance to nicotine addiction and, if they do smoke, theysmoke fewer cigarettes ...ng the critical role this enzyme plays in nicotine addiction gives anew target for developing more effective medications to help people stopsmoking." Re...Hopkins Study Shows Languishing Addictions Drug Really Works
...s about how effective it is in the first stages of addiction treatment and doubts that it would be accepted by ...s. "It could become a valuable addition to heroin addiction programs. Its convenience compared with methadone is a great advantage for addicts who hold jobs," ......ties of heroin and cocaine," says Roy Wise,PhD, an addiction expert at the National Institute on Drug Abuse. "The findingis important because it shows that there are some important similarities betweenthe mechanisms of addictions for different drugs." The idea that the brain chemical dopamine and its ...Vanderbilt University Medical Center Forms Institute For Coffee Studies
... and study theseagents in cell cultures and animal addiction models. "We would like to see whether chlorogenic acids or other components can have aneffect on animals' alcohol self-administration," Martin said. "The idea is that,perhaps, drinking coffee can have a beneficial effect on people who aredepressed an...Good news for "wusses": Research links pain sensitivity to gene
...ld offer the ability to predict a person's risk of addiction to opiate drugs. The research involves bot...ir studies of several dozen volunteers frompain or addiction clinics with those from other labs to report on severalhundred human mu genes. They found ...W.M. Keck Foundation gives USC $110 million
...iseases such as manicdepression, schizophrenia and addiction disorders. "The Initiative will bring together scores of USC scientists, physicians andphysician-scientists to work on common problems," Ryan said. "The Initiative'sgoals include the construction of a new $40 million, 125,000-square-footneurogenetic ...Response to cocaine linked to biological clock genes
...es and vertebrates andthat has been linked to drug addiction in humans. In the August 13 issue of Science, Dr. ...tization in fruit flies. Researchers studying drug addiction or circadian rhythms yearn to understand themolecular actors playing key roles in these and other fu...Jefferson scientist hopes to answer the question, 'Why is it so hard to quit smoking?'
...earchers are delving into the genetics of nicotine addiction for answers Some people would never thin... of the most intriguing theoriessays that nicotine addiction is due to a combination of both environmentalinfluences and factors hard-wired into the brain. Some ...... major symposium, the chemistry of various typesof addiction treatments will be explored, including: - Stopping...y drinking could help serveas predictors of future addiction problems. (see page 107, MEDI 157, on Monday,August 23, at 9:45 a.m., at the Convention Center, R09...Scientists identify brain chemicals involved in 'switching on' cocaine addiction
...ins of mice that appear to play a major rolein the addiction process. Their study appears in the September 16 i...ta-FosB was activating and how this contributed to addiction was a mystery. To learn more about the role of delta-FosB in the addiction process, researchersat Ya...National Institute on Drug Abuse launches National Drug Addiction Treatment Clinical Trials Network
...will more rapidlymove promising science-based drug addiction treatments into community settings. NIDA s...will provide a researchinfrastructure to test drug addiction treatments in real-life settings withdiverse patient populations. The CTN will foster partnerships ...Smells may trigger alcohol craving, and relapse, among alcoholics
...lar relapse rates for alcohol, nicotine and heroin addiction suggest that the relapse mechanisms for several addictive disorders may share common biochemical, behavioral or cognitive components. Yet no controlled studies have definitively shown any single or combined intervention that prevents relapse in a fa...How alcohol gives, and then takes away
... through withdrawal. Mental diseases, including addiction and alcohol dependence, may indeed be "all in your head." But not in the way you might think. Researchers have learned that alcohol may be particularly damaging to the brain's reward pathways, specifically dopamine and serotonin neurons. This dama......anisms of an extremely inducible protein. And now addiction researchers are interested in MT's function in relation to alcohol's neurotoxic effects. "This is one of the first few studies that has looked at the expression of metallothionein in the brain," said Michael Aschner, professor of physiology and pha...Some alcoholics may self-medicate with carbohydrates between drinks
...pted by observations of patients attending a local addiction treatment center; about 50 percent of those in treatment for alcoholism reported extreme cravings for carbohydrates, particularly sweets, upon abstinence from alcohol. Moorhouse called this a "biological drive." Researchers examined the response of ...Rum and 'coke' combo far worse on the brain, study shows
...or benefit of this study lies in helping to tailor addiction treatment," says Bolla. "Long-term use of these drugs actually is damaging to the very parts of the brain that make it possible to quit. So you have to work around that." "If you did these cognitive tests on people as soon as they begin a treatmen......area (VTA), a region of the brain stem involved in addiction and feelings of euphoria. The VTA is also one of s...ggests a role for the neurotransmitter in the drug addiction process. Previous studies have identified CART peptide in areas of the brain directly affected by co...