Newly Discovered Gene Halts Cell Division and May Have Cancer Link
...nt of the original cell. But if the fibers fail to anchor to one of the centromeres, the corresponding chromosome pair can't separate normally and MAD2 puts the brakes on cell division. Dr. Benezra speculates that MAD2 is only one of several genes involved in triggering this cell division checkpoint. In ye...Cholesterol Anchor Helps Signaling Proteins Direct Development
...ecule helps cause the split and then serves as the anchor for the hedgehog signal," says Jeff Porter, Ph.D., a postdoctoral fellow and first author of the paper. "After spending two years searching for what we thought might be a new molecule, this was like finding out Santa Claus is your dad--hard to believ...... use a chemical subunitcalled a disulfide group to anchor the oligonucleotides to the gold electrodes.The disulfide groups bind strongly to gold, acting as a kind of glue between theDNA strands and the electrodes. Then the scientists use lengths of double-stranded DNA to span the distance between th...... rear wheels and two robotic arms that anchor the chair like crutches or ski poles and pull it from the front or push it from behind. To climb a stair, the arms pull the wheelchair up and over the raised ledge then rotate behind the device to push ...Northwestern Hosts Public Forum On Future Of Biotechnology
...scussion moderated by award-winningtelevision news anchor and commentator Mary Laney. Monday's speakers includegene therapy pioneer Dr. R. Michael Blaese of the National Institutes of Health.In all, 30 industry leaders, including innovators from large pharmaceuticalcompanies and small startups, academic res...Bioreactor Grows Cells That Produce Possible Anti-Cancer Protein
... a forest of microscopic polyester fibers that anchor living cells in place. As the cells grow and repro...vides a very high surface area for the cells to anchor on in three-dimensional space,” said Yang. “But the major difference is that other bior...Scientists Show For The First Time How Leprosy Bug Targets Peripheral Nerves
...mina consists of molecules called laminin-2, which anchor to theSchwann cells via molecular hooks called laminin receptors and mediates cellularcommunications from the environment outside the cell to the Schwann. A moleculecalled dystroglycan, a component of a protein assembly called thedystrophin-glycoprot...UF Scientist Seeks Super Sea Oats
...torms andhurricanes. The plants found on the dunes anchor the sand, decrease winderosion and deflect wave action," Kane said. "Without the dunes, the damagethat would occur during storms and hurricanes, particularly in developedareas, would be catastrophic. "Protecting the dunes protects people," Kane said....Research Bears Fruit, And Patents
...lackberryindustry." Stiles says that "Harry is the anchor of our group. He hybridizes parent plantsthat may contribute desirable traits -- such as fruit quality, diseaseresistance, and winter hardiness -- to progenies of seedlings that all of usevaluate for adaptation to our different climates and growing c...Gene triggers formation of sensory cells in the ear
...intosupport cells that surround the hair cells and anchor them in place within theinner ear. The microscopic hairs that sprout from such cells cover inner ear surfaceslike wheat in a Kansas field. When sound or head motion creates ripples acrossthe array of hairs, that motion is translated into nerve impul...Protein studies reveal sophisticated control of nerve communication
... yotiao holds near theNMDA receptors. Whenever the anchor protein releases it, PKA stimulates thechannels to allow in more calcium ions. Yotiao's other closely held enzyme, called type 1 protein phosphatase (PP1),has the opposite effect: it downregulates NMDA receptors, or slows the flow ofions. Steven Tav...First International Congress on Telehealth and Multimedia Technologies Story Ideas
...eointegration (placing metal implants into bone to anchor a prosthesis). Theconsultation looks at innovative technology for a finger reattachment, and a newimplant technology for a mouth defect. The second consultation is with Dr. Satoru Nagata, of Japan, a world leader inear reconstruction and a plastic s...Researchers find key to growing, differentiating human cells
... A forest of microscopic polyester fibers anchor living cells in the bioreactor. This allows cells to grow and reproduce as they do in the body, clinging to the fibers as they would to strands of human proteins. Liquid nutrients course ste...UF researchers find painless electrical stimulus helps restore hand movement for stroke patients
...cil -- or, worse yet, preparing meals. Now he can anchor a piece of steak with a fork to cut it and once again clutch an apple. The turnabout came after McClellan participated in a University of Florida study that used a slight electrical current to painlessly stimulate the muscles of his arm. He was one ...Even the Immune System works with Pincers
...eering techniques in such a way that it lacked the anchor peptide which is used for the membrane attachment on the immunological active cells. As all antibodies of the immunoglobulin IgG and of the allergy triggering IgE consist of similar amino acid sequences and also have similar Fc recep...Gene found to contribute to deadly form of breast cancer
..., move around the body, cling to each other and to anchor locations, and form blood vessels to feed themselves. Armed with that knowledge, the U-M team set out to study the influence of the over-expressed RhoC gene by itself by inserting the gene from tumor cells into normal breast cells, in a process cal...Disconnect between skin cells implicated in common skin cancer
...ke adherens junctions. The alpha-catenin needed to anchor the junction was missing. Changes in the skin of the knockout mouse were dramatic and largely unexpected. The epidermis was thick and disorganized. The characteristic cell shapes of each of the skin's four layers were distorted, making it hard to tel...Amphibian mortality linked to global climate change
...ntal devices, which include boxes they designed to anchor the toad eggs at different distances below the surface of the lake in order to learn whether a thicker blanket of water better protects the eggs from the damaging effect of ultraviolet radiation. "We have found that water levels are shallower during...Doctors failure to reevaluate asthma severity hurts wheezing sufferers
...asthma severity estimates and that these estimates anchor their treatment decisions," says Gregory Diette, M.D., an assistant professor of pulmonary and critical care medicine at Hopkins. "Doctors need to frequently update their severity assessments in order to provide care that meets the patient's needs." ......ted with protruding chemical receptors that weakly anchor liquid crystal in a well-defined orientation along the film's surface. When these receptors are exposed to the specific chemical that is the object of detection, however, they bond more strongly with that target chemical than they do with the liquid ...