New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
... finding suggests the possibility of a new kind of antibiotic that couldrecognize the unusual structure, jam the...lly catalyzes thechemical reaction. Any successful antibiotic must plug into the active site,blocking its action, to kill the bacteria. At Duke, Raetz and...Proteins Interacting With RNA And DNA Are Surprisingly Similar
...ches itself to RNA,making itpossible for a certain antibiotic to fight bacterial infection,is remarkablysimilar ...ecause the rateof proteinproduction is doubled. An antibiotic called thiostrepton works by attaching to both theL11 proteinand the ribosomal RNA of infection-caus...Blood Test Can Identify Some Children With Strep-Related Behavioral Disorders
...children, possibly through the use of preventative antibiotic treatments.Some kids with OCD or tic symptoms never get over how they're treated byothers. Our hope is that with more research, we can change the outcome forthese children." Leonard is professor and director of training for child andadolescent psychi...Common Childhood Virus Poses Threat To Adults, Research Shows
...oing to get better,and we can decrease unnecessary antibiotic use.”...Chemists Develop High-Throughput Method To Synthesize And Screen Novel Antibiotics
...ram level. That might make it possible to develop antibiotic skinpatches. The patches have an advantage over pills, because thepatient would not have to remember when to take medicine, anddoctors would not have to worry that the patient did not finishall the medication. The most promising antibiotics have been...NIDR Supports Total Genome Studies Of Major Oral Pathogens
...eased tissues ("scalingand planing"), coupled with antibiotic therapy. Despite such extensivetreatment, the con...cies will assist in developing newdrugs to counter antibiotic resistance, or to select candidate proteins forvaccine development. Aa sequencing data will be made ...Peptic Ulcer Treatment Improves Health, Saves Money
...for H. pylori, the recommended course of action is antibiotic treatment to eradicate the bacteria---a regimen that nearly always cures the disease in a matter of weeks. However, millions of people were diagnosed before the link between ulcer disease and H. pylori was documented. The large majority have be...Detective Work Uncovers New Tick-Borne Disease In North Carolina And The Southeast
... a mild systemic illness. They were treatedwith an antibiotic and they quickly recovered. During the same period, severalother camp dwellers developed Rocky Mountain Spotted Fever or ehrlichiosis.One person died. Kirkland's research, published in the December 1997 issue of the journal, Archives of Internal Med......ind legs,secretes a substance that functions as an antibiotic and prevents bacteriaand fungi from invading the ants' nests and infecting the members of thecolony. The development of this gland is believed to be associated withthe evolution of the ants' social system, which has been a key factor intheir tremend...Common Cold Caused By Multiple Viruses
...ary prescriptions on top of the risk of developing antibiotic resistance. Mild upper respiratory illness, also known as the common cold, is identified by a set of symptoms.These symptoms can include inflamed sinuses, nasal congestion and a sore throat. Studies done asearly as the 1960s have identified rhinoviru...Drug-Resistant Infection Once Found Only In Hospitals Now Present In Community
...e described as previous hospitalization orfrequent antibiotic use, history of intubation, an underlying chronic disorder,presence of a catheter, history of any surgical procedure, or household contactwith a person who has identified risk factors. The researchers also found interesting differences between hospit...Antimicrobial Resistance: Issues And Options
...eloped resistance to penicillin. Since that time, antibiotic resistance has risen dramatically, posing a threat...der control. Fighting the problem of antibiotic resistance will require a better, more coordinated system of surveillance, as well as an increased e...Biochemists Gain Crystal-Clear Insight into 'Ancient' Enzyme
... job. The findings also may offer new targets for antibiotic compounds thatcould disrupt this key process in bacteria to kill them, the researcherssaid. The biochemists reported in the May 1 issue of Science thatthey had obtained the crystal structure of the protein that is part of theenzyme "ribonuclease P...New Vancomycin Structure May Point To Path For Overcoming Antibiotic Resistance
...n of bacteria resistant tovancomycin, the powerful antibiotic physicians turn to when others fail. The manwas on...e search for new andmore effective versions of the antibiotic with the discovery of a novel form ofvancomycin. The Penn X-ray crystallography results, published i...Cost Effective Prescribing For Duodenal Ulcers
...tablished but small differences in the efficacy of antibiotic regimens can have a big influence on the comparative cost effectiveness of eradication strategies. In a commentary, Delany and Hobbs point out that prescribing for dyspepsia is now the largest single area of cost for primary care, 500 million per ye...New Model Makes It Possible To Predict Emergence Of Antiviral Drug Resistance
...ug resistance in many infectious diseases prone to antibiotic or antiviralresistance, including HIV. "The method...tool to predict the likelihood of future levels of antibiotic orantiviral resistance for numerous infectious diseases, including HIV," saidBlower. A tool to predi...Interleukin-12 Helps Control Mycobacterium Avium Infection
...al trial to test IL-12 incombination with standard antibiotic treatment regimens. MAC is an infectioncaused by ..., when they combined IL-12 with clarithromycin, an antibiotic effectiveagainst M. avium in both humans and mice, the reduction in M. avium was 100-foldgreater tha...Micro-Plants Yield Pharmaceutical New Wave
...health benefits as pharmaceuticals - anti-cancer, antibiotic and improved heart function drugs-have been found." "These tiny plants are unique packages of all the components needed to support life, and are therefore a tremendous source of untapped biochemicals with health benefits and wealth-generating po...New Gene Therapy Technique Results In Efficient Gene Delivery
...ers introduced a gene conferring resistance to the antibiotic neomycininto the viruses. They added the gene-carrying viruses to the cells and thenexposed the cells to neomycin. To their surprise, the researchers sawcolonies--demonstrating cells had become resistant to neomycin and thus had beeninfected by the v......mors. Squalamine, previously shown to have antibiotic and anti-canceractivity, inhibited the growth of brain cancers called gliomas implanted in theflanks of rats by disabling blood vessel growth, or angiogenesis, say theauthors of the studies, published in the July 1 issue of the journal CancerResearch...