Researchers determine genetic cause of Timothy syndrome
... According to Keating, discovery of the genetic basis of Timothy syndrome has implications for understanding the function and importance of calcium channels in general. "Our findings showed that the mutated region is required for inactivation of the channel, which was not previously appreciated," he sai...'Most recent common ancestor' of all living humans surprisingly recent
...or author on the paper. Chang established the basis of this research in a previous publication with an intentionally simplified model that ignored such complexities as geography and migration. Those precise mathematical results showed that in a world obeying the simplified assumptions, the most recent...Genetic differences might help distinguish thyroid cancers
... genetic changes in thyroid cancer cells, form the basis for a valuable diagnostic tool, says Eng, a recipient of the Doris Duke Distinguished Clinical Scientist Award. "Our work begins to elucidate the fundamental differences and similarities between these two types of thyroid cancer, which shoul...New Arizona State center brings science to policy on issues of water resources and urban growth
...th in arid regions by providing a sound scientific basis to the decisions that balance growth with finite water resources. The Decision Center for a Desert City (DCDC) is one of three new National Science Foundation-funded centers that will investigate human decision-making under climatic uncertainty. The...Cardiac arrest may hinder ability to learn certain tasks
... "These changes could be part of the physiological basis for memory deficits and other behavioral changes that patients often report following an attack." The study appears in a recent issue of the European Journal of Neuroscience. Mice were put into two groups one group underwent surgically induced......rmore, the improved understanding of the molecular basis of disease has led to "real optimism that a new generation of improved medicines is just around the corner," Professor Duncan said. New drugs and new delivery systems both come under the "nanomedicine" umbrella. Drug delivery systems are needed to e...Bush nominates NJIT space explorer Louis Lanzerotti to NSF governing board
...(NSF). Eight prominent nominees were named on the basis of their distinguished service in science and engineering research. They will fill six-year-terms. The Senate will confirm the nominations. Lanzerotti, a consulting physicist to Bell Laboratories-Lucent Technologies, Murray Hill and a member of th...DNA barcode finds four new bird species
...sts traditionally have classified organisms on the basis of their physical characteristics. They use DNA too, but current techniques are labor intensive and difficult to compare. Zoologist Paul Hebert, Ph.D., at the University of Guelph, the first author on the PLoS Biology paper, proposed that a ...Anthrax enzyme images reveal secrets of antibiotic resistance, suggest new drug design
...bioterrorism weapon. The finding could also be the basis for a broad-spectrum antibiotic to treat a variety...r way, our new molecule looks like it could be the basis of a very effective new antibiotic against anthrax bacteria." In addition, because many other infec...Brown research reveals key insight into memory-making
...urs, even days, and is believed to be the cellular basis for memory. AMPA receptors on the membrane of the information-receiving neuron, known as the postsynaptic cell, act like gates, opening in response to chemical messages from a neighboring neuron. During LTP, extra AMPA receptors appear, increasing sy...Poplar DNA code cracked -- a step in combating global warming?
... will identify the genes in the poplar DNA. On the basis of mathematical algorithms, the researchers predict that the poplar has around 50,000 genes, and they anticipate that about 10,000 of them are not found in Arabidopsis and are therefore possibly 'tree-specific'. A variety of applications With the ...$7.5 Million grant to Yale researchers for role of viruses in cancer
...more rapid progress in understanding the molecular basis of cancer," said DiMaio. ......search devoted to better understanding the genetic basis for the healthfulness of milk. The symposium will be held at COPIA: The American Center for Wine, Food & the Arts in Napa, Calif., and is sponsored by the California Dairy Research Foundation. Media interested in attending should contact Jennifer Gia...Genes expose secrets of sex on the side
...do not migrate as far as women. On the basis of the genetic work, women's rate of migration had been pegged as eight times higher than men's. The UA team didn't think local marriage practices could govern global-level patterns of genetic variation. But variation in the Y-chrom...Resveratrol synthase uncovered: Cyclization specificity of type III polyketide synthases
...from the Salk institute illuminates the structural basis for tetraketide cyclization in stilbene synthase, ... at the Salk Institute has revealed the structural basis for the specificity of this critical reaction. To do this, the Noel group generated the first crysta...Cockroach-like robot leads new research effort
... try to understand the mechanical and neurological basis of locomotion. The grant is one of six totaling nearly $30 million through NSF's Frontiers in Integrative Biological Research (FIBR) program, which supports integrative research that addresses major questions in the biological sciences. "The hallmar...JCI table of contents September 15, 2004
...as 1 in 3,500 individuals. The underlying genetic basis and the clinical symptoms vary, but generally the result is profound vision loss, most often caused by the death of retinal neuronal through a form a cellular suicide called apoptosis. In many cases the vasculature in the retina also becomes atrophie......th celiac disease. "These findings may provide the basis for novel therapeutic approaches in celiac disease aiming at suppressing uncontrolled CTL activation and conversion into LAK by blocking IL15 or NKG2D," suggests Dr. Jabri. A second study led by Dr. Sophie Caillat-Zucman from Equipe Avenir-Inserm in ...Columbia research to examine gene influence on severity of peridontal disease, therapy response
...ral Surgery. "We intend to identify the molecular basis of the wide spectrum of responses to periodontal bacteria, and use this information to reduce the risk of periodontitis and develop new, more targeted therapies." The patient's individual immuno-inflammatory response to the bacterial challenge is bel...Berkeley Lab soil scientist Margaret Torn receives Presidential Early Career Award
.... "These are key factors in radiative forcing, the basis of global warming." Torn heads the Carbon Project for DOE's Atmospheric Radiation Measurement Program (ARM), a team of eight scientists plus support staff based at Berkeley Lab who gather data at ARM's Southern Great Plains site in Oklahoma. Equippe...