Tag: "budding" at biology news

CAK Activation Of Plant Cell Cycle: Scientists Find Another Piece In The Jigsaw Puzzle To Help Explain Why Plants Do Not Develop Cancer Spontaneously

...from arabidopsis, a common weed, into budding yeast mutants that had a defect in genes responsib... yeast CAKs. In this way they could complement the budding yeast mutations with arabidopsis genes and identify a plant CAK gene. Remarkably, the p...

Evidence From Old Tumors Foretells Which New Breast Cancer Patients Will RequireAdditional Treatment

...nesis -- growth of new blood vessels to supply the budding tumor-- was an equally valid predictor; 92 percent of patients with a lowmicro-vessel count (MVC) survived at least 14 years versus only 70 percent ofthose with a high vessel density. "Our study provides the best clues to date about how to treat pat...

UF Researchers: Gene Therapy Replaces Critical Protein In Animal Model Of Often-Fatal Lung-Liver Disease

...ogist Barry Byrne a fewyears ago. UF is home to a budding A1AD research program, under the direction of Dr.Mark Brantly and funded in part by the Miami-based Alpha One Foundation,that will feature a basic science laboratory focused on the disorder'smolecular mechanisms; a clinical research unit directed tow...

Small G-Proteins Make A Big Difference -- Nerve Cell Signalling Is Regulated By Arf-GTPases And Their Activators

...espass through a sophisticated cycle of fusion and budding reactions, and theefficiency of these reactions determines the vesicle supply that is ready fortransmitter release at any moment in time. Uri Ashery and Volker Scheuss in the laboratory of Jens Rettig at the Max PlanckInstitute for Biophysical Chemis...

Vanderbilt Medical Students Study Effects Of Vibration On Infant Health

... other investigators continue theresearch that the budding researchers began last year. The study compared the abilities of a standard foam mattress and a gel mattressin different combinations to lessen the vibration during routine transportconditions. The research expanded on prior work that showed the infa...

Jefferson scientists show drug is effective against a Hepatitis C Virus model in the laboratory

...nomes but similar methods of envelopedevelopment - budding from the endoplasmic reticulum (ER)," Dr. Block says. "Wethink they will all be very sensitive to N-nonyl-DNJ, since this drug blocks thefirst step in ER glycoprocessing which is needed for some but not all proteinsto fold in the ER." In both HBV and...

Deadly to cattle and humans, prions may help other organisms survive, researchers find

...ike prion structures. They did this for a range of budding yeasts, the group that includes the kind used for centuries in baking and brewing. Using their genetic system for testing prion function, they were able to show that despite the long evolutionary distance separating the various yeast species, the ...

Experiments point to new theory of skeletal development

...hers discovered that the future uniqueness of each budding embryonic digit is determined by the webbed tissue...hat the interdigital tissue (ID) that lies between budding digits is responsible for instructing them as to what they will become. Specifically, each ID instru...

A molecular motor's key role in cell birth

...ol. 406, No. 6799, pp. 1013-15), was worked out in budding yeast cells. But the study is expected to prompt ...The results, she found, were defects in mitosis in budding yeast cells: The Kar9 protein was not carried into the bud, the mitotic spindle was no longer guided...

Penn State researchers unravel key facts about how a virus exits a host cell

...quitin, a 76-amino acid polypeptide, as crucial to budding (the maturation and release of a virus from the ce... identify the parts of Gag that actually drive the budding process. Unfortunately, understanding how Gag works is half the story. Scientists also needed to kno...

Study provides new details of 'the birth of a virus'

...ly the case. The possibility of interrupting the budding process marks the significance of this recently pu...nt of ubiquitin ligase, which encourages the virus budding (Dana-Farber) and the maturation of Gag, the final stage in which the virus becomes infectious (NIAI...

Science and Amersham Pharmacia Biotech grand prize: "jumping DNA" discovery explains immune system evolution

...ay to study cohesion proteins linking sisters in a budding yeast model. At least three classes of proteins participate in binding, Ciosk determined while working at the University of Vienna. A substance called APC (Anaphase Promoting Complex), or cyclosome, then liberates a "sister separating" protein, Esp1,...

Mysterious ways of the heart

...o show that variety may not only add vitality to a budding romance, but the heart as well. Further, the scientists say they have developed a simple computer algorithm that can help decipher the heart's complexity and use it to distinguish between diseased and healthy hearts. Under normal conditions, timing ...

Researcher finds that important fungal "scaffolding" genes belong to one of four classes

...ses of cytokinesis and deposition of new growth in budding yeast versus filamentous fungi, however, said Momany. Still, numerous similarities between septins allowed Momany and other members of her laboratory, Jiong Zhao, Rebecca Lindsey and Patrick Westfall, to find four classes orthologous fungal septins...

Neuroscientist studies brains of bizarre-looking mammals

...formed. Instead of following the normal pattern of budding and growing out directly from the body, the moles distinctive nose rays form as fleshy cylinders on the side of the animals muzzle before detaching and unfolding forward. Looking in detail at the neural connections of individual rays of the star, Ca...

A gateway for Ebola/Marburg viruses

...rafts have been implicated in entry, infection and budding of a variety of pathogens including intracellular bacteria and viruses such as HIV. In the March 4 issue of The Journal of Experimental Medicine, Aman and colleagues from the US Army Medical Research Institute of Infectious Disease, demonstrate that ...

Unexpected links found between many RNA viruses

...troviruses, a protein called Gag similarly forms a budding structure called a capsid that envelops the viral RNA and the Pol enzyme -- a reverse transcriptase that copies RNA to DNA. These capsids are formed in a structure called the plasma membrane, where retroviral replication takes place. This replication...

The next generation of scientists recognized at Johns Hopkins

...cation in such journals validates the efforts of a budding scientist or research physician, recognition within Hopkins -- not to mention the award checks -- can be an important boost for young investigators. "Having my work accepted for publication is a great feeling, but receiving recognition from people ...

Researcher traces gene development in 'last common link'

...vo," as Gibson-Brown affectionately refers to this budding discipline, combines the principles of traditional evolutionary and developmental biology in examining the change in gene sequence and regulation that over time lead to the development of new species and eventually new body plans. "We seek to un...

Structure reveals details of cells cargo-carriers

...omplex works: A component called Sar1 launches the budding process by anchoring itself to the ER membrane. Sar1 accomplishes this feat by changing its shape through a chemical reaction called GTP binding. This shape change also enables Sar1-GTP to recruit a second component called Sec23/24, which attaches to...

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