Tag: "context" at biology news

Alzheimer's disease is not accelerated aging

...o image amyloid deposition, we can look within the context of how the deposits change structure and function of the brain. Are there antecedent causes? Are some individuals more at risk? Are some areas of the brain more vulnerable and is that why memory is more affected?" ...

Far more men than women favor routine paternity testing at birth

...ame, whether you ask it by itself or ask it in the context of other questions, and no matter what order the questions are in," Rohwer said. Smaller groups of those surveyed were questioned further about their responses. A high number of women who favored routine paternity testing said they wanted t...

Bronfenbrenner book sums up human development

...opment." Because of the book's emphasis on social context within the bioecological theory (and Bronfenbrenner's role in shaping educational and public policies, for instance, as a co-founder of the Head Start program), the book is intended for audiences across disciplines, including psychology, human ecolog...

$2.7 million grant to support creation of virtual zebrafish atlas

...iming of gene expression during development in the context of a whole, living organism," Cheng said. "Strong similarities between fish and mammalian development have led to the discovery of new insights that would have been difficult to obtain using other models." The atlas initiative started in 1999 when re...

A liking for sweets, combined with novelty seeking, may predict alcoholism

...it is important to place this information into the context of what this means for a clinician and for a lay person, added Garbutt. First, this method is not being proposed as a means to diagnose alcoholism. Rather, I would view the significance of the findings as contributing to our ability to understand s...

New genetic hypothesis for the cause of autism

...t of the oligogenic model can be considered in the context of possible environmental factors affecting the risk of de novo imprinting defects. Non-genetic factors could affect the risk for an epigenetic form of autism," the authors conclude. If the MEGDI model is correct for autism, it could also be releva...

Molecular staples shape a cancer killer

...eir ability to kill cells -- when removed from the context of the complete protein. This has been one of the greatest obstacles associated with using short peptides as therapeutic agents, and has hindered their legitimacy as pharmaceutical lead compounds. By making the peptides more resistant to degradation...

JCI table of contents: 1 September, 2004

...es the work by DiGiovanni and colleagues into this context and details how this study advances our understanding of and the development of treatments for cancer. TITLE: Disruption of Stat3 reveals a critical role in both the initiation and the promotion stages of epithelial carcinogenesis AUTHOR CONTACT...

Advances in tumor angiogenesis Dendritic cells co-opted to the dark side

...the dendritic cell precursors are put in the tumor context they form blood vessels that are functional," notes Conejo-Garcia. In a mouse model in which ovarian tumors expressed high amounts of the proteins beta-defensin and VEGF-A, dendritic cell precursors were attracted to the tumor, where they turned into...

Heartless worms hold clues to cardiac arrhythmias, sudden death

...eculate that KCR1 might be useful in a therapeutic context to prevent HERG block." The investigators are now using the C. elegans tool to search for novel interacting proteins that modulate HERG drug block. Any new proteins they find may have therapeutic potential for preventing acquired long QT syndrome. I...

Sweet success in targeting sugar molecules to cells in living animals

...ed polysaccharides, in disease is best done in the context of multiple cells, said Bertozzi. "All the interesting biology we want to study takes place at the level of whole organisms. This is a general feature of glycobiology; polysaccharides exert their function largely at the systems level," she said. This...

New model can aid in understanding immune system diseases

...gical functions related to Epstein-Barr within the context of a whole organism, said Gail Bishop, Ph.D., Distinguished Professor of Microbiology and Internal Medicine in the UI Roy J. and Lucille A. Carver College of Medicine and a research career scientist with the Department of Veterans Affairs (VA) Iowa C...

Putting energy into heart protection

... the University of Dundee places these data in the context of what is currently understood about the molecular mechanisms for altering energy use under conditions of stress and how these finding might provide new directions for therapy in heart disease....

JCI table of contents, 16 August, 2004

... the University of Dundee places these data in the context of what is currently understood about the molecular mechanisms for altering energy use under conditions of stress and how these finding might provide new directions for therapy in heart disease. TITLE: AMP-activated protein kinase mediates ischemic g...

Using statistics to decipher secrets of natural mutation

...tly of each other, rather than taking into account context effects, in which the identity of neighboring nucl...tors have been working on how to take into account context effects, I think we are doing it in more rigorous, more complete way," said Green. Without such a ri...

APS announces the winners of its 2004 postdoctoral fellowship in physiological genomics

...urthering understanding of the human genome in the context of the whole body. The Fellowship was established to provide training that enables outstanding young scientists to combine the tools of cellular and molecular biology in the setting of the whole animal. Through these fellowships, awarded annually s...

Genetic mutation linked to more aggressive breast cancer found more often in African-Americans

...c/race difference in p53 expression." Taken in the context of breast cancer, this study's novel use of molecular biology has opened "the door to improved understanding of ethnicity-related variation in breast cancer risk and outcome," writes Dr. Newman....

JCI table of contents, 2 August, 2004

...f Medicine and Science, places these data into the context of the difficulties of treating stroke victims, an... University of Kentucky, present these data in the context of what is currently understood about the interaction of the natural and adaptive immune response an...

Stroking up cellular therapy

...f Medicine and Science, places these data into the context of the difficulties of treating stroke victims, and what additional information beyond this study is required to best understand how these data will be useful for understanding and treating stroke patients. ...

Firefly compound lights up 'protein dance' in living animals

...pected, and as a result it's become clear that the context of protein-to-protein interactions significantly affects what proteins can do," he explains. "That's what lets us get away with so few genes -- the same protein can do different things based on when or where it's used." Scientists have studied these ...

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