Tag: "cell" at biology news

Leader in cancer treatment and prevention research honored

...g that retinol is effective in preventing squamous cell skin cancer. Following this work, he developed a p...rs of skin carcinogenesis, including proliferating cell nuclear antigen (PCNA), p53, polyamine levels, and apoptosis. Together with his research group, the ...

NIH awards $18.2m to The Burnham Institute to develop Center on Proteolytic Pathways

...ak down, regulates the four fundamental aspects of cell behavior: division, death, differentiation, and motility. Understanding this process is critical to designing new therapies based on promoting or inhibiting cellular behaviors. A particular strength of the Center is its emphasis on the use of activ...

International study findings link acne-like rash to effectiveness of new targeted cancer treatment

...rface of some cells and plays a role in regulating cell growth. Cetuximab interferes with the growth of cancer cells by binding to EGFR. It is approved by the Food and Drug Administration in the USA for use with the cancer drug irinotecan for colorectal cancer that has failed other treatments. It is also ...

Researchers determine genetic cause of Timothy syndrome

...ium channels are pore-like proteins that nestle in cell membranes and control the flow of calcium into and out of the cell. Calcium is one of the most important signaling molecules in the body, and perturbing calcium transport can cause a wide range of disorders. Howard Hughes Medical Institute invest...

Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds

...niversity of Pittsburgh Cancer Institute. Before a cell undergoes division, its DNA is replicated and comp...nto identical copies of each chromosome inside the cell nucleus. The chromosomes are then segregated during cell division, so that each daughter nucleus rec...

Molecular motor implicated in tissue remodeling

...directionally, it can serve as a clutch, assisting cell locomotion along networks of collagen in tissues. Further, motion along the precisely aligned collagen filaments directs the proper development of individual tissue types. The model of MMP-1 action revealed by Goldberg and his colleagues might help e...

Chemical derived from vitamin-E shows early promise as cancer drug

... Because cancer may result from just one normal cell going awry, Kline and former graduate student Karla Lawson also used special microscope equipment to identify smaller cancer lesions. The equipment could pinpoint the injected cancer cells in the animals because the cells had previously been genetica...

Scientists sequence genome of kind of organism central to biosphere's carbon cycle

...its brethren, it is encased by a frustule, a rigid cell wall delicately marked with pores in patterns distinctive enough for scientists to tell the species apart. Another new finding reported in Science concerns the unusual way the diatom metabolizes silicon to form its characteristically ornate silica ...

EMBO Gold Medal 2004 goes to Spanish scientist

...ot only connecting telomeres to DNA repair and the cell cycle but also to chromatin epigenetics. Recent discoveries Most recently, the research group produced the first characterization of mammalian telomeric heterochromatin and the activities that regulate it. Other recent groundbreaking contributions...

Researchers find color sensitive atomic switch in bacteria

...e number of related membrane receptors involved in cell signaling that govern biological functions," Spudi... science in the genomic era is the crucial role of cell membranes in normal cell function and disease states," said Spudich, who holds the Robert A. Welch D...

Gladstone investigator Mike McCune wins prestigious NIH Director's Pioneer Award

...edical College and his doctorate in immunology and cell biology from The Rockefeller University. He completed a residency in internal medicine at UCSF and then, after a postdoctoral fellowship in pathology at Stanford, went on to found two biotechnology companies, SyStemix and Progenesys. These companies ...

AAAS US Presidential Candidates' Forum

...t www.aaas.org/election *** WASHINGTON, DC -Stem cell research, climate change and many other scientific...nced research support portfolio, put changing stem cell policy near the top, and promised to elevate the Science Adviser position to its former status as As...

New study indicates arsenic could be suitable as first-line treatment in type of leukaemia

...es in cancer cells, inducing apoptosis programmed cell death. It also appears to correct the gene responsible for making a flawed protein (the PMLRAR fusion protein) that causes APL. The research team used RT-PCR2 techniques to confirm the diagnosis of APL by identifying the rogue gene in their study pa...

New molecular link key to cellular proteins involved in cancer progression, other diseases

...cellular proteins that are known to be involved in cell development and progression of diseases including ... will be published in print in October. Within the cell nucleus, DNA is wrapped tightly around nucleosomes, globular structures composed of four abundant pr...

Safety of isoflavones in dietary supplements targeted by Illinois initiative

...sor of molecular and integrative physiology and of cell and structural biology, will study patterns of gene activation affected by isoflavones through both estrogen-dependent and estrogen-independent receptors in breast tumors. They also will examine gene regulation in breast tumor systems, especially th...

Phase II trials of second-generation antisense cancer drug planned following successful early study

...e production of clusterin, a protein that protects cell survival and is widely distributed in body tissue....nge of activities, including apoptosis (programmed cell death). When it is over-produced, as it is many major cancers, clusterin can stop cancer cells from ...

Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases

...in concert." Portnoy, a professor of molecular and cell biology and of public health and a member of UC Be..., Portnoy said, but it probably has to do with its cell biology, the fact that it grows directly in the cell cytosol. There it stimulates the one pathway th...

Pacific Northwest team unveils largest virus proteome to date

...esearchers were also surprised to find that when a cell is infected, the HCMV virus incorporates into itse...y in Nelson's lab. "In addition, one of these host cell proteins pointed us to sites in the cell where viruses are assembled." The prevalence of host ...

Microscopic miracles

...tainly embrace the opportunities arising from stem cell research, tissue engineering research and device miniaturisation. Real opportunities exist to design nano-sized bioresponsive systems able to diagnose and then deliver drugs (so-called theranostics), and to design systems able to promote tissue regen...

UCSF scientist Joe Derisi named MaCarthur Fellow

...cientist Tim Mitchison. Theriot, a microbiologist, cell biologist, and biophysicist, is focused on unraveling the secrets of bacterial infection. In 1997, Eva Harris, PhD, formerly of the UCSF laboratory of Nina Agabian, PhD, in the UCSF Department of Stomatology, was named a MacArthur Fellow for...

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(Date:10/19/2014)... Oct. 19, 2014 (HealthDay News) -- New stem cell-based ... lead to new treatments, a new study suggests. ... human intestinal tissue in a lab dish. They then ... for studying intestinal disorders, according to the researchers. ... diseases and conditions that can cause intestinal failure, from ...
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