Tag: "cells" at biology news
Brain Protein "Rescues" Neurons From Atrophy
...enter neurobiologists have protected growing brain cells
from atrophying from disuse by treating them with ... new technique of providing neurotrophins to brain cells
that, for the first time, allows researchers to determine precisely which cells
received the substan...
Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...evitably devoursthe free NO gas that endothelial cells
produced to dilate the vessel,hemoglobin simultaneously releases the SNO molecule it had been carrying.One "ineffective" NO is exchanged for another "protected"NO. Blood pressure remains constant and blood flow maintained in order topromote oxygen tr...
Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
...er levels of topoisomerases in some cancer cells
than in normal cells," Dr. Wang said. Many topoisomerase-targeting drugs "freeze" the enzyme while it is clutching two ends of a severed DNA strand before rejoining them (see figure). "Basically, what this type of drug...
New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...o interfere with the malignant machinery of cancer cells
to kill them. In a second paper in the October iss...cientists reported new understanding of how cancer cells
acquire the ability to avoid the natural death, called "apoptosis," that normal cells
Researchers Pinpoint Site For Petit Mal Seizures In Brain
...in the brain. These receptor proteins are found in cells
throughout the body, and respond to a neurotransmi...n of GABAb receptors at the junction between nerve cells
where signals are transmitted from one nerve to the next. She showed that GABAb receptors that recei...
Tumor Suppressor Gene Located In Liver Cancer Cells
...material, they compared strands of DNA from tumor cells
and surrounding normal tissue, and discovered mutations in the tumor samples. The discovery of identical mutations in more than one tumor indicated potential "hot spots" -- regions of the gene that may be more susceptible to mutation. "One mutation ...
Rosemary May Have Anti-Cancer Properties
...s initiation phase, or the transformationof normal cells
to cancerous ones. The study, directed by John Mil...The results were similar:DMBA's binding to mammary cells
was reduced by 66 percent. The researchers also found that rosemary's effectiveness against tumor ...
Heat-loving Microbe Repairs Its DNA With Light
...ciallydamaging the DNA of live S. acidocaldarius cells
with UVradiation, whose effects on DNA are precisely known. As expected,the vast majority of cells
were unable to reproduce followingthis treatment. If the cells
were then exposed to visible light, ...
Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...s, Sullenger introduceda defective gene into mouse cells
growing in a test tube. Then he engineereda ribozyme to recognize a short stretch of RNA near the genetic defect andsplice in the corrected sequence, which Sullenger had produced artificiallyand attached to the ribozyme tail. When he introduced the r...
Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
...1 gene appears to be made almost exclusivelyin the cells
that line blood vessels. While researchers aren't ...rowth inhibitor. For example,TGF-_ stimulates skin cells
to divide, making TGF-_ an excellent wound-healer. In earlier research, reported in the December 1...
Transgenic Rice Plants Resist Insects, Drought And Salt Damage
... made the transgenic rice were first introduced to cells
of three Japonica rice varieties with the Biolistic particle delivery system, the "gene gun" invented at Cornell by plant biologist John Sanford and electrical engineer Edward Wolf. Cornell Research Foundation has applied for patents on the transgen...
Mutate Or Die: New Polymerase Gives Desperate Yeast An Option
...A polymerase family: a last-gasp enzyme that yeast cells
turn towhen all attempts to fix damaged DNA have f... humans alike. Damaged DNA that is copied to other cells
carries a muchgreater risk of causing cancer and other diseases than healthy DNA does. By copying da...
International Research Team Clones New Skin Cancer Gene
...ew gene, called PTC, is essential for keeping skin cells
under control. "Genetic mutation of PTC is the key step in development of skin cancer,2 said Allen Bale, M.D., senior author of the Cell paper and director of the Cancer Genetics Program at the Yale Cancer Center. The discovery paves the way for nov...
... With the exception of early fetal cells, all cells
appear to have poisonousproteins stashed beneath t...anes. Like spies with cyanide pills underthe skin, cells
pack these suicidal enzymes away for extreme emergencies,releasing them only when neighboring cells
Photosystem I -- An Intermediate Step -- May Not Be Necessary For Plants
...e view that photosynthesis -- the process by which cells
in green plants convert the energy of sunlight int...researchers explained they found that mutant algal cells
were able to grow and survive in near-normal conditions. "No pun intended, but this sheds new light...
Researchers Find Possible New Route to Making Cancer Cells Vulnerable
...ects the cell against poisons, but resistantcancer cells
have many times the normal amount of MDR protein to protectthem from chemotherapy drugs. These cells
work overtime, expelling chemotherapydrugs that would normally kill a cancerous tumor and allowing r...
Protein Glitch May Be Early Problem In Inherited Alzheimer's
...be directly causing the widespread damage to nerve cells
seen in FAD, but it may interfere with other proteins that could. Like dominoes falling, a change in presenilin sets off a chain reaction. "Think of it as a cascade," says Sisodia. "We don't know how many steps there are in this cascade, but we have...
Virginia Tech Researchers Receive Patent For Rapid Virus Detection Technology
...sed on the fact that many viruses causesusceptible cells
to break open and release their cellular contentsa...se of compoundsthat are normally only found within cells
is indicative of thepossible presence of a virus," says Hagedorn. The test detects a specific compo...
Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...ng why somebacteria escape attack by immune system cells
called macrophages, whichare designed to disable a...ygenor NO is present. In fact, bacterial cells
attempt to control both excess oxygen and excessnitrogen with the same OxyR transcription factor. ...
Salvage Gene Is At The Root Of Many Mutations
...ur cells. Uncorrectedabasic sites can be lethal to cells
because they act as vast potholes, halting the pol...ght to occur because mutations permit precancerous cells
to overcome the geneticdefenses against unlimited cell proliferation and migration." The Roches...
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