Tag: "circadian" at biology news

UT Southwestern biochemist honored with NIH Director's Pioneer Award

...hile a clearer picture of the relationship between circadian rhythms and depression might impact drug discovery in the treatment of potentially significant forms of mood disorder. "Taking major risks and achieving momentous accomplishments have characterized Steve McKnight's career," said Dr. Kern Wilden...

Serotonin metabolites in mollusks suggest pathways for human therapies

...ollusks is similar to melatonin, which resests the circadian clock in humans, Stuart and colleagues suggested in the Journal of Neurochemistry. "This is the first quantitative measure of how serotonin metabolites are related to a behavioral state in marine mollusks," Sweedler said. "What we do not know is wh...

Rising childhood leukaemia incidence prompts conference

...in early childhood, light pollution, melatonin and circadian rhythms, placental transfer to the foetus of damaging agents, medicines in pregnancy and delayed transgenerational susceptibility through the germline.(ends) Notes to Newsdesk: The conference is taking place at Church House, Dean's Yard, Westminster,...

Research suggests unborn children may be at risk from environmental pollution

...de, for example, diet in early life, melatonin and circadian rhythms, light pollution and medicines in pregnancy. It is hoped that out of the conference will be born an agenda for future research and CHILDREN with LEUKAEMIA will be launching a 1m fund to support research in priority areas....

Analysis of biological clock may lead to greater understanding of human disease

(Santa Barbara, Calif.) Our biological clock, or circadian rhythm, is upset by travelling across time zones, ...le. New studies of the computational models of the circadian rhythm of fruit flies show that the internal clock is robust, that is, not easily perturbed. These s...

Circadian clock genes reign in duration of fruit fly copulation

... that two genes representing key components of the circadian clock somehow also influence sexual behavior in th... The new work reveals that, in fact, at least some circadian clock genes can also control the duration of behaviors over a much shorter time scale--in this case,...

2nd media alert First Scientific Conference on Childhood Leukaemia

...in early childhood, light pollution, melatonin and circadian rhythms, placental transfer to the foetus of damaging agents, delayed transgenerational susceptibility through the germline, the presence of pre-leukaemic cells in babies that make them vulnerable to environmental triggers, and so on. The conference ...

Testing the fitness of biological clocks

... and cancer. Microscopic pacemakers--also known as circadian clocks--are found in everything from pond scum to ...e Colin Pittendrigh of Stanford. He suggested that circadian clocks might be beneficial even in an unchanging environment. There was some indirect support for th...

Enzyme activation appears key in helping internal clock tell night from day

...in of rats where, like in all mammals, the primary circadian clock is located. The clock is a dynamic biologic...ion of PKG-II leads to "significant phase delay of circadian rhythm." The clock is literally forced back in time to repeat the necessary sequence of protein com...

New 'clock gene' uncovered

...een working toward an understanding the biology of circadian rhythms -- the cyclic, clock-like expression of ge...ious sleep disorders, many of which are related to circadian rhythms, say the scientists, who report their findings in the latest issue of the journal Neuron. ...

Got the time?

...the course of a 24-hour day, a phenomenon known as circadian rhythmicity. In their study, Ueda et al. first ide...ntified genes that are expressed in high amplitude circadian patterns. Such genes demonstrate cyclical expression irrespective of variations in exposure to light...

Coordinating power of circadian rhythms keeps estrus and pregnancy on track

...the daily patterns of biological behavior known as circadian rhythms are able to control complex events such as...ng and metabolism, have a 24-hour rhythmicity. The circadian rhythms that underlie these patterns are controlled in the brain by a molecular clock that has a per...

Long-term heart damage may result from constant confrontation and defeat

...time-domain indexes of heart rate variability, (2) circadian rhythmicity of heart rate across the chronic chall...-term effects took into account the changes in the circadian rhythms of HR and the consequences on myocardial structure. Results The study found...

New research shows that the seasons may be involved in onset of menopause

... which is generally accepted to play a role in the circadian rhythm (the 24 hour time clock that governs different physiological processes), could be involved. Melatonin binding is found in the ovaries and it also influences ovarian steroid hormone production. Other research has shown that the harmony of these...

Loss of circadian genes results in epilepsy

...now discovered that the combined deletion of three circadian genes, encoding the PAR bZip transcription factor ...nd TEF), all of which display distinct patterns of circadian accumulation: In tissues with high amplitudes of circadian clock gene expression (like the liver), P...

Beware cancer, insomnia and liver disease UH students are taking aim

... for research in biological clocks. Also known as circadian rhythms, biological clocks are the mechanisms that...oughput screening of drugs that regulate mammalian circadian rhythms. This would be a more cost-effective approach to the more traditional phase shift experimen...

Artificial light-dark cycles expose circadian clocks at odds with each other

...biologist demonstrates that there are at least two circadian clocks in the mammal brain, one that sticks strict...housands of cells called neurons with synchronized circadian activities. But the neurons in the nucleus can be grouped into at least two secondary clocks that ca...

Unnatural light-dark cycles expose duelling circadian clocks

...als, the endogenous daily pacemaker that regulates circadian rhythms like sleep and wakefulness is localized to...eus (SCN), which is composed of many neurons whose circadian activities are in synchrony with one another. By exposing rats to a very short day/night schedule a...

High profile publications in biology and biochemistry on rise at UH

...f them, for instance, work on different aspects of circadian rhythms. "Even within Houston, we have tremendous biomedical sciences," Dryer said. "We have three other major institutions within the city actually four if you include Galveston so we have to go after smart science, recruiting people focused on...

How do animals exposed to 24-hour light retain their wake-sleep habits?

...rdiac physiology. They recorded the mammals' daily circadian rhythm using heart rate to show the rhythm of slee...ght and demonstrated the Aschoff effect, where the circadian activity pattern changes quantitatively with the intensity of the light. This group took on a 26-hou...

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