Tag: "cystic" at biology news
Study explores gene transfer to modify underlying course of Alzheimer's disease
...tudies to deliver different genes to treat cancer, cystic
fibrosis, and Parkinson's disease. "Until now, it has not been used in Alzheimer's disease," Arvanitakis said. "The vector is no longer a true virus as it cannot replicate on its own and must be in the presence of another virus to be active. The vect...
Using statistics to decipher secrets of natural mutation
...illion base pair DNA segment known as the "greater cystic
fibrosis transmembrane conductance regulator region," which was sequenced in the 19 mammals by Eric Green and his colleagues at the National Human Genome Research Institute. To concentrate on the neutrally evolving DNA, Hwang and Phil Green excluded ...
Retroviral gene therapy? ASLV, HIV, and MLV show distinct target site preferences
Many diseases (including inherited disorders like cystic
fibrosis to cancer) have a genetic component and gene therapy holds the promise of restoring compromised genes with their healthy counterparts. That promise was quashed when a teenager -- Jesse Gelsinger -- suffering from a rare hereditary liver diso...
Jefferson Lab detector technology aids development of cystic fibrosis therapy
...searchers develop a new gene therapy technique for cystic
fibrosis. "Our core expertise is instruments...eland, is using the small animal medical imager in cystic
fibrosis gene therapy studies along with colleagues Assem Ziady and Pamela Davis. They're researchin...
New UCF researchers, college will help fight Alzheimer's disease, cancer
...Third World countries, and other illnesses such as cystic
fibrosis, Teter said. The new researchers and expanding biomedical programs will give UCF a stronger foundation for a medical school as it investigates the need for one in Central Florida. An ongoing study will determine the viability of a medical sc...
U of T research answers key question in biochemistry
...s in folding, a problem linked to diseases such as cystic
fibrosis and Alzheimer's. ...
Drug prevents chemotherapy-induced hearing loss, study finds
...d as an amino acid supplement to treat bronchitis, cystic
fibrosis and other respiratory illnesses, prevents ototoxicity by binding to the cisplatin platinum molecules, rendering them inactive. It also is a known free radical scavenger, hunting down these highly reactive atom clusters believed to cause simi...
New technique images gene expression in mice
...eoretically correct the genetic defect that causes cystic
fibrosis, one of the most debilitating, and ultima... system. Affecting approximately 30,000 Americans, cystic
fibrosis afflicts mostly children and, at one time, took its victims in their teens. Researchers hav...
American Society for Microbiology honors Timothy Yahr with 2004 Merck Irving S. Sigal Memorial Award
...eatment of Pseudomonas infections in patients with cystic
fibrosis, AIDS, or other disorders, for whom treatment options are often quite limited. Yahr's other research interests have important clinical implications as well. As a postdoctoral fellow at Dartmouth Medical School, Hanover, New Hampshire, ...
Tracking cystic fibrosis with mice
...igins of a disease. This had not been possible for cystic
fibrosis because the equivalent genetic defect did... modified mice to generate the typical symptoms of cystic
fibrosis. As a result, he was able to demonstrate for the first time the long suspected relationship...
Researchers show cystic fibrosis defect in mice corrected with turmeric extract
...ound in the spice turmeric, corrects the defect of cystic
fibrosis in mice. Cystic Fibrosis (CF) is a debilitating and ultimately fatal genetic disorder, caused by the failure of a chloride channel, the Cystic Fibrosis Transmembrane conductance Regulator (CFTR), to reach its proper place ...
Scientists correct cystic fibrosis defect in mice with turmeric extract
...that a compound in the spice turmeric corrects the cystic
fibrosis defect in mice. This research is reported...ions in the gene encoding CFTR are responsible for cystic
fibrosis. In the most common form of cystic
fibrosis, the CFTR protein is trapped inside the cell, a...
APS announces four 2004 Young Investigators awards
...ses on developing treatments to circumvent or cure cystic
fibrosis. He is also studying cells that line the distal portion of the male reproductive tract and have implications in treating infertility and developing male contraceptives. Additionally, Dr. Schultz researches mammary function and the preventi...
Leading experts in field of gene therapy to meet in Minneapolis
...h as cancer and AIDS, cardiovascular diseases, and cystic
fibrosis will be showcased in a variety of educational workshops and symposia. Program topics will also feature: Innovative approaches of gene therapy Long term follow up of gene therapy clinical trials International harmonization of regulatory s...
Study reveals important new factor in cystic fibrosis lung inflammation
...g piece of the puzzle of how lung damage occurs in cystic
fibrosis (CF). CF is a life-threatening, genetic disease that causes chronic lung infections and impairs digestion. The discovery, published in the current issue of Nature Immunology , provides impetus for the development of novel therapeutics th...
UT Southwestern researchers discover link that could aid in treatment of kidney cyst diseases
...essive polycystic kidney disease, a common genetic cystic
disease that affects between one in 10,000 to 40,000 babies and is often fatal in the first month of life. In addition, they found that the PKHD1 promoter was directly regulated by the HNF-1 protein. "Mutations in HNF-1, the cause of MODY5, interfer...
Evolution caught in the act
...t to numerous disease states, like Alzheimer's and cystic
fibrosis, that result from defective protein folding. " Disulfides are also vital for the activity of most proteins that are injected into people for medical purposes, such as insulin and TPA, a blood clot dissolver that is injected into people wh...
Approved drug blocks deadly anthrax toxin
...cquired infections and a scourge for patients with cystic
fibrosis. All three are also considered potential bioterror agents. "We all hope that the bioterror attacks of 2001 never recur," said Tang, "but if something happens, it would be nice to have better treatment options."...
Cystic fibrosis gene linked to fatty acid defects
BOSTON The discovery that cystic
fibrosis (CF) patients have an imbalance of fatty ...led that this fatty acid abnormality was unique to cystic
fibrosis. According to Brian P. O'Sullivan, MD, who led the research at UMass Memorial Medical Cente...
JCI table of contents, February 2, 2004
...ure not the only cause of antibiotic resistance in cystic
fibrosis The organism Burkholderia cepacia is as...th severe morbidity and mortality in patients with cystic
fibrosis, and is resistant to many common antibiotics. This resistance is mediated by the inability ...
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