New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...search team used RT-PCR2 techniques to confirm the diagnosis of APL by identifying the rogue gene in their study patients. This further enabled them to establish a new classification for acute myeloid leukaemia (AML). Part of the disease process in APL is due to a translocation involving chromosomes 15 and 17.......h is expected to bring significant advances in the diagnosis and treatment of disease. She said: "This is still just the beginning. In the longer term, nanomedicines research will certainly embrace the opportunities arising from stem cell research, tissue engineering research and device miniaturisation. Real ...A test case for DNA barcodes to identify species
...ve test of the utility of DNA barcoding for either diagnosis of individuals or discovery of species." Future studies will have to determine whether these results can be generalized to animals in other ecosystems, but the authors argue that constructing a comprehensive library of barcodes will facilitate such e...Gene expression in liver tumors and patient prognosis
...vestigated variations in gene expression in HCC at diagnosis and compared them to patient survival over time. The researchers examined 91 HCC tissues, 60 matched non-tumor surrounding liver tissues, and 18 normal liver samples. They isolated total RNA to derive complementary DNA and characterized each...Researchers identify distinctive signature for metastatic prostate cancer
...is important," he said. According to Beachy, both diagnosis and treatment of prostate cancer could benefit from understanding the role of Hedgehog activation in carcinogenesis. "If clinicians could use Hedgehog activation perhaps measured by detecting some marker in the blood to distinguish indolent from me...Growth hormone and IBD: Reduction of intestinal inflammation, promotion of growth
...young as 18 months and can be particularly hard to diagnosis in children. Initial symptoms may be nonspecific ...eight loss or delayed growth. The average delay in diagnosis is three years from the onset of symptoms in children. About 60%-90% of children with Crohn's and 15...Novel IBD therapeutic approaches reported from Washington Univ., Barcelona, LSU at APS meeting
...ry areas has key implications in the pathogenesis, diagnosis and treatment of IBD. A major effort has been directed toward identifying and characterizing the adhesion glycoproteins that enable leukocytes to bind to vascular endothelial cells. Drugs that specifically target adhesion molecules involved in leukoc...New genetic hypothesis for the cause of autism
...ve the same DNA, are much more likely to share the diagnosis than fraternal twins. However, experts have not yet identified the specific genetic components related to autism, and many experts believe that multiple genes are involved. Researchers, led by Yong-hui Jiang of Baylor College of Medicine in Houston,...Rising childhood leukaemia incidence prompts conference
...dence (1-4 years) and to improved registration and diagnosis of the disease, may be partly true, but they cannot plausibly explain the overall pattern of data now at our disposal," said Professor Coleman. It is the worrying upward trend, an inability to pin down the causes and emerging concerns that cancer tr...Disease diagnosis, drug development focus of UH prof's biochip research
HOUSTON, Sept. 1, 2004 Leading the way to disease diagnosis and drug development, biochip research at the Univ...nd have applications in genetic screening, disease diagnosis and drug development. "The design of biochips depends critically on our understanding of how biol...Pacific Northwest National Laboratory gets $10 million from NIH to build virtual lung
...ction. This will greatly assist in the evaluation, diagnosis and development of treatments." PNNL established its leadership in the field in 2001 when it rolled out the model of working rat lungs it called "the virtual respiratory tract." At the time, it offered the clearest picture yet of how pollutants enter...Highlights of American Chemical Society national meeting in Philadelphia, Aug. 22-26
...ucts , potential biomarkers for improving disease diagnosis and new findings about the health benefits of foods and food supplements are among the topics addressed at the 228 th national meeting of the American Chemical Society, the world's largest scientific society, in Philadelphia, Aug. 22-26. The meet......l have widespread implications for HIV management, diagnosis and prognosis." This groundbreaking news is in part due to the development of a new technical tool that permits cloning of the virus....Gene associatied with lupus identified
...these genes will be important to developing better diagnosis and treatment of the disease. In SLE, a person's i...s, and this leads to significant challenges in the diagnosis and management of lupus. "If we know which genes predispose a person to lupus, we may be able to dia...Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...August 18, 2004) - Despite improvements in earlier diagnosis and treatment, cardiovascular disease is far and away the leading cause of death in the U.S. and the world. According to the latest posted statistics, heart disease causes 700,000 deaths in the U.S. each year, with the number of adults diagnosed wit......metable approach may also have applications in the diagnosis of circadian rhythm disorders. This new approach to the horology of the body has been validated in mice of varying genetic backgrounds and in principle can be applied to any organism exhibiting biological clock activity, a range that spans the livin......d increasing focus on evidence-based medicine, the diagnosis of a spider bite continues to be based mainly on suspicion and fear of spiders, and diagnosis of a chronic ulcer on stories of suspected spider bites causing devastating necrotic fasciitis (fles...Early clinical treatment can halt progression of Alzheimer's disease, UCI researchers find
...le, emphasizing the need for better means of early diagnosis and treatment of patients with Alzheimer's disease. The findings are reported in the Aug. 5 issue of Neuron . "Current estimates indicate that by the middle of the century, 20 million Americans will suffer from Alzheimer's disease," said Frank LaFe...Molecular therapeutics advance fight against brain cancer
...mor Association. To further narrow the gap between diagnosis and effective therapy, physicians at the University of Pennsylvania Health System now offer several promising approaches to brain tumor treatment, including novel imaging for oncologic neurosurgery and refined genetic testing for tumors to better tar......ic of Georgia's soil, and reiterated that accurate diagnosis and rapid treatment were essential in any case of botulism infection. "The important thing is that physicians quickly identify the illness based on the clinical syndrome," said Dr. Sobel, "and that upon suspicion of botulism the physicians contact th...