Rare childhood genetic syndrome identified
...dismantles the automatic closing mechanism, so the door just stays open." As a result, cells are overwhelmed by an influx of calcium. Because calcium-channel blocking drugs can ameliorate calcium overload, these medications may be useful for treating arrhythmia and cognitive deficits in individuals with...Researchers devise potent new tools to curb ivory poaching
...me hope to obtain permanent exemptions. "Once the door is cracked open, they try to force it open all the way," Wasser said. He noted that a number of countries have kept ivory stockpiles since the 1989 ban, and the small central-African nation of Burundi has a stockpile of 80 tons despite the fact tha...Gene expression in liver tumors and patient prognosis
...f patient survival and these findings may open the door to the development of more targeted therapies for liver cancer patients. While gene technology has previously been applied to some specific aspects of liver cancer, researchers led by Dr. Snorri Thorgeirsson of the NIH's National Cancer Institu...Sugar-coated sea urchin eggs could have sweet implications for human fertility
... that eggs can change the lock in the carbohydrate door too." Biermann is first author of a paper describing the findings in the September-October edition of the journal Evolution & Development. Co-authors are Jessica Marks of the University of Bergen in Norway; and Ana-Cristina Vilela-Silva, Michelle Ca...Single isolated mouse skin cell can generate into variety of epidermal tissues
... not require genetic manipulation. "This opens the door for applying this method for isolating human cells," Fuchs explains. The findings represent a culmination of years of work in the Fuchs lab on the science of hair and skin growth. This path of discovery has seen many hallmarks of progress, including...Genuine stem cells found in skin might treat hair loss, wounds
...air and skin," Lowry said. "These results open the door to that possibility."...Study reveals first genetic step necessary for prostate cancer growth
...ent of prostate cancer. The finding could open the door to new tests that predict whether the cancer will become aggressive and the development of treatments to prevent the condition from progressing. The study, published in the Sept. 1 issue of Cancer Research, found that when mice are engineered to lo...Probing the surface of white blood cells to enhance immune system medicine
...nto a site on this protein--sort of like wedging a door open so it doesn't shut," explained Higgs. "And we want to make sure that wedge doesn't prop any other doors open that should stay closed."...Advances in tumor angiogenesis Dendritic cells co-opted to the dark side
...ng cells led tumors to shrink. "This has opened a door to a new therapeutic approach, which was not envisioned before," says Coukos....Genetic clues found for common congenital brain disorder
...der," added Dobyns, "but now we have a foot in the door for understanding this and other cerebellar defects." A genetic test could improve prenatal diagnosis. Currently, detecting Dandy-Walker with ultrasound images is difficult and often uncertain until late in a pregnancy, usually after 20 weeks. Mos...MIT research that stops pain of needle jabs gets FDA approval
...st thing is that approval of this device opens the door to many new uses such as glucose-sensing or insulin delivery for diabetics," said Langer, who explained that the microscopic openings created in the skin are much too small to see, but large enough for molecules relevant to medicine to pass through. ...When is a mouse like a test tube?
... over-produce sialic acid. The technique opens the door to non-invasive imaging of sugars as markers of disease." "Irrespective of its biological relevance, the method introduced by Bertozzi and colleagues is remarkable as a chemical process," Tirrell added in his commentary. "The fact that specific chemi...Last of known genes identified in complex obesity syndrome
...es and proteins with a known function, opening the door to figuring out what's really happening in people with the condition. "We can use BBS3/ARL6 and its known function -- binding the molecule GTP -- as a great place to start to unravel the details of the other BBS proteins," says Nicholas Katsanis, Ph....Emory researchers map structure of anti-cancer molecule
...cell division. The discovery potentially opens the door to the creation of more effective cancer treatments. "Uncovering and mapping the structure of this model system will assist scientists around the world in creating new compounds that hopefully will lead to new cancer drugs," says researcher...Genetic mutation linked to more aggressive breast cancer found more often in African-Americans
...y's novel use of molecular biology has opened "the door to improved understanding of ethnicity-related variation in breast cancer risk and outcome," writes Dr. Newman....Genetic discovery could dramatically reduce need for liver transplants in children
... the Journal of Clinical Investigation opens the door to the possibility of new treatments for children ...es our initial observation in humans and opens the door for the future development of agents to control inflammation and progression of disease," Dr. Bezerr...Malignant cancer cells generate mice through cloning
...'s oncology department, this research opens up the door to developing cancer animal models in which researchers could ask epigenetic questions. "Although studies are ongoing, these findings have provided initial clues of the relative contributions of the epigenetic versus genetic lesions in the developmen...Clusters of alterations on PIK3CA gene found in brain cancers
...n oncogene associated with brain cancers opens the door to screening processes that can identify patients for treatment strategies, as well as development of targeted molecular therapeutics aimed controlling brain cancer development through regulation of the errant gene, Yan said. Yan is an assistant pro...Free electron laser reaches 10 kW
...rovement in performance, the achievement opens the door to many new applications, some foreseen, and some are simply very pleasant surprises," said Christoph Leemann, Jefferson Lab Director. "We look forward to operating this exciting new machine and carrying out the many experiments planned for it." The...Scientists identify molecular link driving spread of skin cancer
...y issue of the journal Cancer Research , open the door to the prospect of targeted therapeutics capable of preventing or limiting the metastasis of skin cancer. "The ability of these synthetic peptides to reduce tumor cell metastasis and angiogenesis and increase apoptosis may be important in the develop...