Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
... bridges and chromosome instability is most likely due to reactive oxygen species that form as the cell is exposed to the various chemicals in smoke. Treating the smoke-exposed cells with different antioxidants, agents that block formation of reactive oxygen species, prevented most occurrences of anaphas...New study indicates arsenic could be suitable as first-line treatment in type of leukaemia
...aemia (AML). Part of the disease process in APL is due to a translocation involving chromosomes 15 and 17. Their results from the RT-PCR analysis suggested that AML should be reclassified by dividing it into two groups APL with t(15-17) and t(15,17) negative AML. t(15-17) negative AML would then be sub-...Alzheimer's disease is not accelerated aging
...ata suggest that changes in executive function are due to age-associated influences on frontal-striatal c... memory loss of Alzheimer's disease is more likely due to changes in the medial temporal lobe memory system, which includes the hippocampus. For brain...New Arizona State center brings science to policy on issues of water resources and urban growth
..."Central Arizona faces an uncertain climate future due to global climate change, annual variability causing droughts and floods, and the urban heat island effect, which has raised nighttime summer low temperatures almost 10 degrees in the past 50 years." "Our team of scientists from geography, ...16 APS exercise research highlights, from reduced flu mortality to proteomics & obesity
...Urbana) Protective effect of exercise on mortality due to influenza in mice. Moderate exercise for four consecutive days post-infection significantly increased survivability to influenza infection. 28.1 Ronald N. Cortright, et al. (East Carolina University, Greenville, SC) African-American women have ...... a federally threatened species have been rejected due to a lack of data that documents declines caused by human related threats. ...$7.5 Million grant to Yale researchers for role of viruses in cancer
...ith DiMaio, she has found that some cancers may be due to inaccurate DNA synthesis by error-prone DNA polymerases. "Working collaboratively on these related projects has enabled us to make much more rapid progress in understanding the molecular basis of cancer," said DiMaio. ...Termites could hold the key to self-sufficient buildings
...r inclusion in a new Sir David Attenborough series due to be screened in 2006. The mounds incorporate a complicated network of tunnels and air conduits designed to channel air flow for the control of internal air quality, temperature and moisture levels. Furthermore, the termites have evolved in such a ...$2.7 million grant to support creation of virtual zebrafish atlas
...nomenal growth in the zebrafish research community due to the zebrafish's compelling experimental characteristics and its capacity to model human disease," said Cheng, who is working with co-investigator Stephen Moorman, Ph.D., of the Robert Wood Johnson Foundation Medical School on the atlas. "This gran...Key stimulator of colorectal cancer identified
...cer (CRC) is the second most common cause of death due to cancer for men and women in the United States It has been known for some time that NSAIDS and other cyclooxygenase (COX) inhibitors reduce the risk of CRC. However, the exact mechanisms of this protective action are unclear. PGE2 is a metabolite o...Targeted therapy knocks out pediatric brain cancer in mice
...ch Hospital in Memphis, Tennessee. "This is partly due to the absence of adequate model systems for testing novel therapies." Dr. Curran and colleagues used a mouse model of medulloblastoma that they had developed to examine whether selective inhibition of the Sonic Hedgehog (Shh) signaling pathway could...Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
... that consumption of many types of fish be limited due to widespread contamination with pollutants, such as heavy metals and dioxins. Second, world wide fish stocks are being rapidly depleted, and fish farming is associated with its own set of environmental issues. Therefore, engineering the production o...US investment firm gives away Rhode Island-sized lands in Chile
... most significant gifts of private land worldwide, due to the size of the land (approximately equal in size to the state of Rhode Island), the ecosystems it contains and their importance to conservation on a global scale. A Tradition Of Local Commitment Since the early 1960s, WCS has been committed t...Brain has center for detecting sound motion
...ng to the researchers, such improvement likely was due to partial recovery because of adaptive changes in her cortex. According to the researchers, their findings "provide evidence of an auditory motion module within the right posterior STG" and that by analogy with the motion-detection region of the vis...JCI table of contents September 15, 2004
...es provided evidence that the hyperplasia loss was due to a reduction in b cell growth and to an extensive increase in programmed cell death. While PDX-1 is known to be important for pancreatic progenitor cell growth, these studies indicate that it also has a vital role in regulating adult b cell pro-lif...Pioneering AIDS researcher to speak at UH
...eak about strides in research that have come about due to the AIDS epidemic in China, where estimates expect the total case load to reach 10 million infected with HIV by 2010. Ho will talk about a DNA vaccine that has already reached phase-I human trial, as well as discuss two more vaccines under devel...Tufts University establishes $4 million dollar tissue engineering resource center
...as grown immensely as a discipline in recent years due to advances in cell and molecular biology, biomaterials science and engineering and bioreactor design and function. Tissue engineering also fosters basic research, by providing physiologically relevant models of cells and tissues. "We've created ...Spontaneous mutation produces new MAO A/B knockout mouse
.... The scientists hypothesize that the mutation was due to elevated levels of the MAO B substrate phenylethylamine in the MAO B knockout mice. Phenylethylamine is a neuromodulator which, when broken down into its metabolites, has been shown to cause mutations in DNA. "Interestingly," says Dr. Shih, "a ...Growth hormone and IBD: Reduction of intestinal inflammation, promotion of growth
...ed growth and intestinal bleeding. This in part is due to impaired actions of growth hormone, a naturally occurring compound that normally acts to promote both growth and healing. About 10%, or 100,000 of the estimated 1 million Americans who suffer from IBD (either Crohn's Disease, or ulcerative colitis...New research suggests early diet may play key role in protecting against childhood leukaemia
...September) will consider evidence that this may be due to differences in diet pattern. The incidence of ...nce that the low incidence of leukaemia in Asia is due in part to the protective effect of turmeric, a spice used widely in Asian cooking. "Some of the kno...