Researchers report new gene test for isolated cleft lip and palate
Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases.... ...The National Institute of Environmental Health Sciences, the National Institute of Dental and Craniofacial...Researchers report new gene test for isolated cleft lip and palate
Researchers report they now can predict whether some parents are more likely than others to have a second child with the "isolated" form of cleft lip and palate, one of the world's most common birth defects, according to results of a study published this week in the . The research was supported in part by the National Institute of Dental and Craniofacial Research and the National Institute of E...Gene linked to cleft lip and palate identified
WHITE PLAINS, AUGUST 19, 2004 -- An international team of researchers has identified a gene variant that is a major contributor to oral clefts and triples the risk of recurrence in affected families, it was reported today in ....... "Cleft lip and cleft palate are among the most common birth defects in the United States," says Nancy S. Green, M.D., medical director of the March of Dimes, which h...Plant respiration not just an evolutionary leftover, study shows
A biological process in plants, thought to be useless and even wasteful, has significant benefits and should not be engineered out -- particularly in the face of looming climate change, says a team of UC Davis researchers....... ....... Over the past two hundred years, scientists...Nature cover story - Only 10% of all large fish are left in global ocean
The cover story of the May 15th issue of the international journal Nature reveals that we have only 10% of all large fish-- both open ocean species including tuna, swordfish, marlin and the large groundfish such as cod, halibut, skates and flounder-- left in the sea. Most strikingly, the study shows that industrial fisheries take only ten to fifteen years to grind any new fish community they enco...Solving the mystery of the dancer mice, and cleft lip too
By watching mice "dance" and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans.... ... A team led by Rulang Jiang of the Center for Oral Biology at the University of Rochester Medical Center found that a gene known as Tbx10...Monkey talk, human speech share left-brain processing
Scans have pinpointed circuits in the monkey brain that could be precursors of those in humans for speech and language. As in humans, an area specialized for processing species-specific vocalizations is on the left side of the brain, report Drs. Amy Poremba, Mortimer Mishkin, and colleagues in NIH's National Institute of Mental Health (NIMH), Warren G. Magnuson Clinical Center (CC), components of...BOSTON, Mass. For the first time in history, the United States is faced with a confirmed case of bovine spongiform encephalopathy (BSE) or mad cow disease within its borders, but according to Northeastern University professor of chemistry Ira Krull there are many more undocumented cases just waiting to be discovered.... "The American public should be concerned, at this moment, there is contamina...Left side of brain activates speech from birth
For the first time, researchers have used functional magnectic resonance imaging (fMRI) to investigate infantbrain activity in response to speech. They found that, almost from birth, the brain's left hemisphere plays the leading role in processing most language functions. Presented Dec. 2 at the 89th Scientific Assembly and Annual Meeting of the Radiological Society of North America (RSNA), the...Purdue scientists discover why we're all lefties deep down
WEST LAFAYETTE, Ind. - It may be a right-handed world, but recent Purdue University research indicates that the first building blocks of life were lefties - and suggests why, on a molecular level, all living things remain southpaws to this day.... ...In findings that may shed light on the earliest days of evolutionary history, R. Graham Cooks and a team of Purdue chemists have reported experiment...Newly invented Endometrial Function Test (EFT®) solves the puzzle of unexplained infertility
A Yale researcher who invented a test to determine whether a woman's endometrium (uterine lining) is healthy and ready for embryo implantation has identified two new biochemical markers that improve assessment of the endometrium.... ...The endometrial function test (EFT®) was created by Harvey J. Kliman, M.D., a research scientist in the Department of Obstetrics, Gynecology and Reproductive...In some patients with chronic fatigue syndrome, left ventricular function may be involved
April 9, 2003 -- (San Diego) Chronic fatigue syndrome (CFS) is a baffling disorder. Some 20 years ago, it was dubbed "the yuppie flu," because the complaints of a similar constellation of problems were reported primarily by women in their 30s and 40s who were well educated and in upper-income brackets. Since the 1980s, CFS has become better understood, which is good news for the estimated 500,00...Right better than left in asthma medication for children
... ...A new, large-scale study shows that levalbuterol, a purified form of the widely used asthma medication albuterol, is effective for children in much smaller doses with fewer side effects than the standard medication. Levalbuterol contains only the biologically active right isomer of albuterol. Albuterols left isomer is inert, at best, and possibly harmful.... ...Albuterol is the most widel...Researchers identify gene causing rare form of cleft palate
The identification of a gene that causes a rare form of the congenital defect, cleft palate, may offer an important insight into human development and the mechanisms involved in the condition.... ...Researchers led by Dr Philip Stanier from Imperial College have found that the sex-linked form of cleft palate (CPX) and an associated form of the disorder known as tongue-tie are caused by mutations...Footprints of early human migration left in DNA
New research published in BMC Genetics examines footprints left in mitochondrial DNA leading to the conclusion that after humans migrated out of Africa to Western Asia around sixty-to-seventy thousand years ago, subsequent migrations from Western Asia resulted in the populating of Europe and Northern Africa.... ...Mitochondrial DNA (mtDNA) is a useful molecule for comparing different human popula...Smoking during pregnancy found to increase risk of cleft lip and palate
............ANN ARBOR, Mich. - Women who smoke while pregnant are 50 percent to 70 percent more likely than nonsmokers to give birth to a baby with a cleft lip or palate, according to a new study by researchers at the University of Michigan Health System. ... ...The risk of the disfiguring facial birth defect rises with the number of cigarettes that a mother-to-be smokes each day, even after fac...Learning how organs tell left from right
. --From all outward appearances, the human body.is symmetrical. If one were to divide the body into two halves, for example,.each side would have a single arm and leg. But a look inside at the internal.organs shows that there is not perfect symmetry throughout the body. The heart.and spleen normally reside on the left side and the liver and gallbladder are on.the right. Furthermore, the organs...Researchers Discover Mechanism Of Cleft Palate Development
.Researchers led by a team of UC San Francisco scientists have identified the.mechanism by which a disfiguring birth defect wreaks its havoc. Cleft palate,.the most common craniofacial birth defect in humans, occurs when the two sides.of the palate do not properly fuse during fetal development, leaving an opening.or cleft in the roof of the mouth.. . Earlier research had already established tha......... ...This news release is also available in .... ... ... ...Washington DC - A team of scientists from Spain and the UK has determined that a...certain curiously primitive group of flatworms are the oldest living ancestors...to all "bilateral" animals-that is, those with a right and left side. These...worms were previously thought to belong to a much younger group of organisms,...and their...Antibodies Know Right From Left
Knowing right from left is essential in many areas of life -- even on.the molecular level. Prof. Meir Wilchek of the Weizmann Institute's.Biological Chemistry Department, working with an international team of.researchers, has now discovered that this ability is particularly.prominent in antibodies, the Y-shaped proteins produced by the immune.system.. . Antibodies fight disease-causing intrude...Earth's Changing Land GCTE-LUCC Open Science Conference - 14-18 March 1998 - Barcelona, Spain... ......Will climate change occur at a a higher rate than the speed at which species...can establish, grow and reproduce? Eight hundred of the world's leading...environmental scientists will address this and other questions at a meeting...sponsored by GCTE/LUCC in Barcelona, Spain on March 14-18, 1998....A National Institute of Allergy and Infectious Diseases (NIAID) grantee in.Seattle has found experimental data to support a new hypothesis about the.genesis of scleroderma, an autoimmune.disorder that primarily affects middle-aged women. .J. Lee Nelson, M.D., and her colleagues report in the Feb. 21 issue of The.Lancet, that women with scleroderma have significantly higher levels of non-self.fe...cientists have identified not just a single gene but a genetic circuit, that when broken, causes cleft palate in newborn mice. The critical points of the circuit represent genes and gene products that interact with one another to direct palate formation. The "surge" that causes the circuit to break is an environmental assault in the form of steroid hormones given to the female mice during preg...