Tag: "earliest" at biology news

New Discovery About Genes Has Implications For Genetic Therapy

...e discovery provides a window into how some of the earliest organisms evolved several billions of years ago si...imilar mechanism that must have taken place in the earliest evolutionary stages of primitive one-celled animals-- at least a billion years ago. "We were inte...

Protein Glitch May Be Early Problem In Inherited Alzheimer's

...rmation of plaques in the brain that are among the earliest signs of Alzheimer's disease. Hopkins researchers currently are looking at mice in which the gene for presenilin is knocked out so that presenilin's function may be revealed by its absence. Scientists estimate that 15 percent of Alzheimer's patients ...

Cholesterol Anchor Helps Signaling Proteins Direct Development

...art disease, actually wears a white hat during the earliest stages of life. In this week's Science, Johns Hopkins and Howard Hughes Medical Institute scientists report that hedgehog proteins, an unusual group of proteins that help shape many features of a developing embryo, pick up molecules of cholesterol t...

Bog Beetle, Misidentified For 85 Years, Is 'Discovered' At Cornell

...s from Maine to Ohio and Ontario to Maryland. The earliest collected specimen found so far belongs to the American Museum of Natural History in New York City, which was found at Palisades on Hudson, N.Y., on April 2, 1907. The collector was not noted on the specimen label. There are also specimens from the...

New Evidence For Corn's Ancestry Could Lead To Insect And Drought Resistant Crops

...roduced fertileoffspring that closely resemble the earliest known samples of primitivedomesticated corn, she s...Americas once they began cultivating it." But the earliest known versions of corn have far smaller ears that bearfewer and tinier kernels, providing silent tes...

Where Fossils Fear To Tread: Scientists Follow Genes To An Ancient Ancestor

...ossils or other physical clues to what the Earth's earliest animals were like. But Carroll and others are now finding powerful evidence that an ancient common ancestor - a worm-like animal from which most of world's animals subsequently derived - invented a set of body-building genetic machinery so s...

NIDR Supports Total Genome Studies Of Major Oral Pathogens

... withimpaired immunity. Candidiasis is one of the earliest and most commonopportunistic infections to occur in the oral cavity of HIV-infectedindividuals. Oral candidiasis causes pain and discomfort and can lead topotentially deadly infections in AIDS patients and other individuals withcompromised immune sy...

New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines

...l be able to see our experiments through, from the earliest laboratorystudies to the final tests of safety and efficacy in humans. And that is veryexciting."...

Novel AIDS-Directed Technology: Approach Permits Optimization Of Existing Drug Therapies And Targeted, Patient-Specific Treatment

...the goal ofcommercializing this technique at the earliest time. We anticipate thatpotential beneficiaries will include AIDS, cancer, osteoporosis, heart patientsand others." "The implications of the technology's capability to quickly and accurately monitor the status and progress of this disease in real t...

At Life's Most Sensitive Stage, Embryos Cope With Stress

...e excision repair is essential for lifeeven at the earliest stages of intrauterine embryonic development of the mouse,"Pedersen said. "We are investigating the response of embryos to injury thatoccurs within the womb, and the mechanisms that embryos use to cope with thedamage, or to initiate a 'self-destruct'...

Jefferson Researchers Find Correlation Between Gene And Endometrial Cancer

...ancer is much more treatable when caught in its earliest stage. The American Cancer Society (ACS) estimates that roughly 36,000 new cases of endometrial cancer will be diagnosed in the United States during 1998. Some 6,300 U.S. women will die from the disease this year....

Study Shows: Just Say NO To Bone Loss

...and localfactors such as nitric oxide. One of the earliest events in post-menopausalwomen is increased osteoclast cell numbers and activity due to diminishedcirculating estrogen. With a better understanding of the antigen recognized byMab 121F and how NO is regulated in osteoclasts, we may be able to develo...

Study Links Viruses And Vascular Diseases

...xplains. "At most, viruses could initiate only the earliest stages of thedisease," he says. "They certainly couldn't block arteries on their own." Damage resembles human diseases Normal mice never develop full-blown atherosclerosis, which makes them imperfectmodels, Virgin says. Nevertheless, he and his col...

New Species Of Winged Dinasaur Named For Yale Professor

...onorof Yale paleontologist John Ostrom, one of the earliest proponents of thecontroversial theory that modern-day birds are descended from dinosaurs. Newsthat the creature had been named for him caused Ostrom to laugh with delight. Dubbed Rahona ostromi ("Ostrom's menace from the clouds"), the fossil...

Precursors To Red Blood Cells Form Earlier Than Previously Thought

...m cells becomecommitted to blood cell fates during earliest stages ofgastrulation. Red blood cells form in two distinct waves. The first waveconsists of primitive red blood cells that form in the yolk sac.The yolk sac is an organ outside of the forming embryo body thattransfers nutrients from the mother to th...

Molecular "Fossils" Of Early Life

...olecules like those that probably gave rise to the earliest life forms on Earthnearly 4 billion years ago, thus creating a biochemist's version of "JurassicPark" populated by exotic molecular "fossils" that have long since becomeextinct. In the May 26 issue of the Proceedings of the National Academy o...

At Last, Zoologists May Know What Is Killing The World's Amphibians

...us of chytrid, a group thought to be relatedto the earliest fungi. Although other chytrids parasitise a range of organisms,from microscopic algae to insects, they have never before been found to causedisease in vertebrates. The fungus, which has yet to be given a scientific name, is known tohave struc...

New Strategy Discerns Early Stages Of HIV Infection, Paving Way For Targeted Study And Therapy

...le to study and tailortreatment to people with the earliest stages of the disease. The researchers set out to overcome this roadblock. They modified the existingHIV test, called an enzyme immunoassay, to make it less sensitive than theoriginal version. They then administered both tests to 579 people with HI...

A Synthetic Peptide Destroys Brain Plaque Implicated in Alzheimer's Disease

... may take many years. Dr. Soto's compoundis in the earliest stages of animal testing. The beta-sheet breaker can cross the blood-brain barrier, according toongoing animal studies by Dr. Soto. His team is also working with animal modelsof other diseases to assess if beta-sheet breaker peptides can be used...

UF Discovery Of Chicken Gene Mutation Aids Study Of Rare Inherited Eye Disease

...et them for genetherapy." LCA-I is among the earliest and most severe forms of autosomalrecessive inherited retinal degeneration. Autosomal recessive diseasesoccur when a person receives a defective copy of a particular gene fromboth parents. The retina, a light-sensitive tissue at the back of the ...

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