Tag: "factor" at biology news

Brain Protein "Rescues" Neurons From Atrophy

...4 or some similar molecule, must be the endogenous factor for which neurons are competing, and that the effects of deprivation are likely to be mediated by such a factor," Katz said. The key to the scientists' discovery was a new technique of providing neurotrophins to brain cells that, for the first time, ...

Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses

...uChE." Abou-Donia said an additional genetic risk factor arises in some individualswho have a faulty form of BuChE, resulting in low enzymatic activity andthus a diminished ability to inactivate drugs or pesticides. This risk factor,which affects only 3 to 4 percent of the population, may boost the toxicit...

Tumor Suppressor Gene Located In Liver Cancer Cells

...he gene -- mannose 6-phosphate/insulin-like growth factor II receptor, or M6P/IGF2r -- acts as a tumor suppr...otent growth inhibitor, called transforming growth factor beta. It disables a positive growth factor, insulin-like growth factor II. The receptor also works ...

Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease

...a potent inflammatoryprotein called tumor necrosis factor alpha (TNFa). To test their idea, the researchers injected the TTP-deficient animalswith an antibody that neutralizes TNFa. In a dramatic and almost completereversal, all signs of disease completely disappeared. The findings support preliminary re...

Duke Researchers Find Second Gene Linked To Blood Vessel Disorder

... with the potent growth factor, transforminggrowth factor beta (TGF-_). Researchers are only beginning to unravel howTGF-_ works. Receptors for TGF-_ are found on the surface of virtually every cell ofthe body. When TGF-_ binds to these receptors, signals are relayed inside the cell. Thecellular response ...

Race Plus Roaches: A Breathtaking Link

...allergens are known to represent an important risk factor for acute asthma, a condition that causes the bronchi of the lungs to constrict. Onset almost always occurs in childhood. Serious illness and even death can result. For example, in Baltimore City, where the study was conducted, asthma is the number o...

Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report

...excess. One way to do that is tohave transcription factor sensors that get turned on when too much oxygenor NO is present. In fact, bacterial cells attempt to control both excess oxygen and excessnitrogen with the same OxyR transcription factor. In human cells, constant vigilance against...

Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease

...excess. One way to do that is tohave transcription factor sensors that get turned on when too much oxygenor NO is present. In fact, bacterial cells attempt to control both excess oxygen and excessnitrogen with the same OxyR transcription factor. In human cells, constant vigilance against...

End Of World Population Growth Projected For 21st Century

...ay?" (ed. W. Lutz),just off press. "The biggest factor affecting population growth is the continuingdecline of fertility in most world regions," says Project Leader WolfgangLutz. Lutz says that as a whole, the world's population will probably increasefrom today's 5.8 billion to around 7.9 billion in 2020...

Genetic Makeup May Explain Why Some Women Smokers Develop Breast Cancer While Others Don't, UB Study in JAMA Reports

...dy, the first to consider genetic variability as a factor in a person's breast-cancer susceptibility to the carcinogens in cigarette smoke, will be published in the Nov. 13 issue of the Journal of the American Medical Association. The results showed that postmenopausal women born with the slow-acti...

Two Long-sought Diabetes Gene Found

...erent mutations in the gene for hepatocyte nuclear factor 1 alpha (HNF-1-alpha) but healthy subjects had normal copies of the gene. A few young normal subjects from these families had also inherited the mutant gene. They are expected to develop diabetes in the future. Finding MODY3 led to the rapid discover...

Pinpoint Gene Control Holds Promise For Nervous System Studies

... turning on in adult mice the genefor nerve growth factor (NGF), a substance that has beendifficult for scientists to study because it's so difficult tomanipulate. Investigators believe the method will make possibleimportant studies into the way our nervous system works. "Thistechnology gives us an unp...

Overweight Cats Risk Disease And Premature Death, Cornell Study Finds

...chers meetings for humans, there is a motivational factor in regular weigh-ins. Make sure the cat is eating what he's supposed to eat and nothing but. Avoid those calorie-rich snacks. Ask your veterinarian if a special weight-reduction diet is appropriate for your cat. Don't go ov...

Scientists Urge Further Study Of Alarming Coral Reef Decline

...est of theecosystem?" Coral reefs are an important factor in the economiesof many nations; for example, they provide key habitats forlobsters and groupers. The reefs also are a major touristattraction. "You could imagine what Australia would be like ifpeople didn't have the barrier reefs to go to," Ostrande...

Scientists Use Magnetic Field As Alternative To Space-Based Zero Gravity

...e gravity-induced stresseson the frog embryos by a factor of 10, which simulated a near-weightlessenvironment. No other ground-based technique has produced a similar reductionin forces and stresses. "The magnetic field actually picked up every single molecule in the embryos,mimicking the type of cell-by-ce...

Houseflies May Transmit Ulcer Bug

...cent becominginfected by five years of age. A key factor in these differences may bethe use of indoor plumbing in developed countries, says Dr. Grbel. Houseflies frequently come into contact with human food andexcrement and have been reported to be involved in the dissemination ofnumerous diseases inc...

Stuttering Appears To Have Strong Link To Family Genes, Researchers Say

...MPAIGN, Ill. -- Genetics appears to be a principal factor in the developmentand persistence of stuttering, say researchers at the University of Illinoisand the University of Chicago. The likelihood a child will begin to stutter and the likelihood of continuingdepend a lot on the family tree and the child's...

Jefferson Scientists Discover Mechanism Of Viral Link To Disease Commonly Associated With Asbestos

...only factor, but clearly there is more than one factor involved in the onset of mesothelioma," said Dr. Giordano, who is also president of the Sbarro Institute for Cancer Research and Molecular Medicine, which is affiliated with the college. "It is a complex mechanism." According to Dr...

Resistance To Leptin Contributes To Obesity

...affects one in three Americans and is a major risk factor fordiabetes, heart disease, high blood pressure, stroke, sleep apnea,gallstones, some cancers and forms of arthritis, according to the NationalInstitute of Diabetes and Digestive and Kidney Diseases (NIDDK), part ofthe federal government's National I...

Newly Discovered Human Protein Provides Important Target For Cancer Therapy

... allowance for cell divisions may be a significant factor in normal humanaging.) "Cancer cells find a way of switching telomerase activity on, whichgives them a tremendous competitive advantage," Dr. Weinberg says. "They havethe potential for continuous reproduction in the body or in cell culture-...

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