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Gene-Altered Mouse May Provide New Insights To Parkinson's Disease, Substance Abuse And Schizophrenia

...released in the knockoutmice, we were astounded to find they make only 5 percent to 10 percent thenormal amount of dopamine, about the same as Parkinson's patients,"said Caron. "Yet we thought the dopamine levels would be much higherthan normal because without the transporter protein, there would be no wa...

Tumor Suppressor Gene Located In Liver Cancer Cells

... from the biological changes involved in cancer to find the genes responsible for these alterations. In this case, however, the functions of an already-identified gene led Jirtle and his team to hypothesize its involvement in liver cancer. "This is an 'old' gene for which we have characterized an importa...

New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics

...e, jam the enzyme and kill bacteria. Bacteriawould find it extremely difficult, if not impossible, to develop resistanceto such a drug, since the enzyme, called LpxA, is necessary to bacterialgrowth, the scientists said. Bacterial resistance to antibiotics has become an important health problemand...

Computer Program For Quicker, More Detailed Mapping

...Myers. The coming maps will also help researchers find the particular DNA markersthat are used to diagnose disease. "The more detailed maps are essentialin identifying disease genes, especially for diseases that are inheritedin a complex manner and aren't due to a defect in a single gene," saidMyers....

Researchers Use Hydrated Lime To Reduce Toxic Selenium Emissions

...enium disposal. The researchers are also trying to find outhow much it would cost to retro-fit a plant for...leniumare going to be," Fan said. "Some plants may find iteasier to install a very expensive wet scrubber to remove allof the harmful byproducts from flue g...

Florida Researchers Discover Gene For Fatal Childhood Disease

... "The next step is to characterize the gene to find out how it doeswhat it does," Kingsmore said. "So far we have a piece of the puzzle. We nowneed to figure out precisely how it causes the disease, how it protectsagainst kidney disease in lupus, and how it makes people susceptible to cancer."...

Photosystem I -- An Intermediate Step -- May Not Be Necessary For Plants

... artificially developed mutants of a green alga to find this new life process. "It is a very important discovery; I didn't believe any of this stuff when it was first reported. I thought it was impossible, but cooperation between the two labs showed it was possible," Owens said. Owens does not know how t...

Researchers Find Possible New Route to Making Cancer Cells Vulnerable

...face.It selectively pumps out toxic chemicals that find their way inside thecell. Normally, the MDR pump protects the cell against poisons, but resistantcancer cells have many times the normal amount of MDR protein to protectthem from chemotherapy drugs. These cells work overtime, expelling chemotherapydr...

Protein Glitch May Be Early Problem In Inherited Alzheimer's

...fect on what the protein does. If researchers can find where presenilin cleaves and the enzyme that cleaves it, intervening at this point with drugs or other treatments might be ideal, according to Sangram Sisodia, Ph.D., an associate professor of pathology and neuroscience. Sisodia and Gopal Thinakaran,...

Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report

...tuallyeverywhere scientists look in the body, they find NO has a role," Stamlersaid. "This study shows why. NO influences myriad body functions becauseNO is a universal signal." The body keeps NO, which is toxic in excess, in balance by sensing how muchNO is present and turning genes on and off to keep ...

A Genetic Skeleton Key

...eady known. While other techniques alreadyexist to find cross-species geneanalogs, this method is far more...d Russianresearchers working at USC -- islikely to find ready applications inbiotechnology, evolutionary biologyand medical research. The researchers, two i...

Ocean Sediments Contain Record of Past Vegetation Fires in Africa

...een studying the marine record as a major place to find out about past carbon dioxide changes. If they've been making the wrong assumptions about how much marine carbon is involved, then their estimates about carbon dioxide in the oceans may be wrong." Current models have not been able to determi...

Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease

...tuallyeverywhere scientists look in the body, they find NO has a role," Stamlersaid. "This study shows why. NO influences myriad body functions becauseNO is a universal signal." The body keeps NO, which is toxic in excess, in balance by sensing how muchNO is present and turning genes on and off to keep ...

Study Shows Songbirds Switch From Bugs To Berries To Fuel Fall Migration

...ns and hawks that also migrate south each fall. To find out whether fall migrants preferred fruit-laden habitat or selectedtheir habitats at random, Parrish and volunteers removed berries from 30-metersquare areas of shrubs and allowed birds to choose between identical habitatswith and without fruit. Thre...

Human-Like Ability, Categorical Perception, Found In Insects

...e low-frequency cricket sound might help the flier find a mate, or at least the company of other crickets....mparable, workable solution. We may now expect to find categorical perception in many different systems, between insects and humans."...

Duke Primate Center Sets October Expedition To Find 'Juliet'

...vide easy accessfor both settlers and hunters, who find the conspicuous, brightly coloredsifakas easy prey. "In fact, on an earlier visit, when I tried to explain to the nativeswhich animal I was looking for, they told me they called this animal 'It-takes-two-days-to-eat,'" Simons said. While the native...

Harvard, Duke Researchers Discover 'Off-switch' Inside Human Cells

...an by screening a huge library ofhuman proteins to find those that interacted with activated G proteins.Structural analysis revealed that one of the candidate proteins they discovered,which they named RGS10, was closely related to the RGS family of proteinsfrom yeast, mouse and other organisms. Previous s...

Duke Ecologist Says Logging Is Creating 'Mahogany Deserts'

...ng each other out," she said. What Snook couldn't find was equally important. There were no mahogany seedlingssuccessfully growing under the forest canopy. Any seedlings she found wereinstead "on roadsides and abandoned agricultural fields," shesaid. Back in the forest, Snook also found young mahogany t...

How Birds Sing

...n or have diminished hearing. "What we can hope to find eventually is: How does learning influence the activity patterns of individual neurons? We're learning how the circuits are put together, and we should gain insight into what elements of the circuit are modified during learning." The research was fun...

Gene Discovery Could Overcome Aluminum Barrier To Higher Wheat Yields Worldwide

... in wheat and rye. "A major objective has been to find genes that breeders worldwide can use to develop n...est that will help plant breeders around the world find rice plants that have genes for greater resistance to zinc deficiency. Sulfides formed in rice padd...

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(Date:12/1/2008)...RNewswire-FirstCall/ -- ViroPharma Incorporated,(...submitted a supplemental,Biologics License Applic...ion,(FDA) for Cinryze(TM) C1 Inhibitor (human) as...oedema (HAE). , The sBLA is based on a re-a...hase 3 acute treatment study of Cinryze and interi...
(Date:12/1/2008)...PRNewswire/ -- Media entrepreneur, television and,... and philanthropist John,Bendheim will be honored...annual "Road To A Cure" Gala, December 2, 2008, at...ell, Chairman of the Board of Governors, co-chairs...an and Fran Solomon. The "Road To,A Cure" Gala i...
(Date:12/1/2008)..., personality illnesses common, study shows , ...atric disorders are common among young adults in t...port shows. , To reach this finding, U.S. resea...nts, aged 19 to 25, who took part in the National ...ions. , The study found that 45.8 percent of th...
(Date:12/1/2008)...with the agency,s goals, commitment and resources ... Responding to criticism that it has done a poor j... Food and Drug Administration released a report Mo..., Among the most important changes in 2008 was t...ps with state and local health departments to prot...
Breaking Medicine News(10 mins):Health News:ViroPharma Submits Supplemental Biologics License Application for Cinryze(TM) to Treat Acute Attacks of Hereditary Angioedema 2Health News:ViroPharma Submits Supplemental Biologics License Application for Cinryze(TM) to Treat Acute Attacks of Hereditary Angioedema 3Health News:ViroPharma Submits Supplemental Biologics License Application for Cinryze(TM) to Treat Acute Attacks of Hereditary Angioedema 4Health News:ViroPharma Submits Supplemental Biologics License Application for Cinryze(TM) to Treat Acute Attacks of Hereditary Angioedema 5Health News:Cedars-Sinai Board of Governors to Honor Ryan Seacrest & John Bendheim at Annual 'Road To A Cure' Gala 2Health News:Few Young Adults Seek Treatment for Psych Disorders 2Health News:FDA Touts Efforts to Enhance Food Safety 2Health News:FDA Touts Efforts to Enhance Food Safety 3Health News:FDA Touts Efforts to Enhance Food Safety 4
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