Brain Protein "Rescues" Neurons From Atrophy
...tober issue of Neuron, the scientists reported the first steps in deciphering the intercellular chemical "l...rophins. Understanding this chemical language is a first step in learning to manipulate the growth of brain cells, the scientists said. Previous studies at D...Duke Researchers Discover Central Role Of Nitric Oxide In Hemoglobin Action
...al Nature, could quickly pay off in developing the first effectiveblood substitute, and may ultimately chan...the Pew CharitableTrusts. Working with Stamler was first author, Duke research associate LiJia, and Joseph Bonaventura and Celia Bonaventura, from Duke's Nic...Dangerous Chemical Combination Presents Possible Scenario For Gulf War Illnesses
...would have remained healthy," Abou-Doniasaid. "Our first task was to demonstrate the safety of each chemicalwhen used individually." The chickens exposed to individual chemicals showed no outward signs ofillness or debilitation, the researchers said. But chickens exposed to anytwo chemical combinations ex......diction and Parkinson'sdisease and may provide the first realistic model for testing new treatmentsfor psyc... post-doctoral fellow. These studies provide the first direct demonstration that the dopamine transporteris absolutely required for amphetamine's releasing...Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
... of the enzyme separate, pulling apart the first DNA segment. At the same time, the second DNA segment is pushed through the severed first DNA segment into the central hole and the C' domains join together (4). The B' domai...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...parts of cABL like a key fits a lock. "This is the first time we've been able to open a window on what activates normal cABL," said Pendergast. "People have been looking for this molecule, or a molecule with these characteristics, for over a decade." In their experiments, Dai and Pendergast discovered that...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
... diseases, the Duke scientists say. "This is the first explanation of what these proteins produced by tri...t work at all or don't work well," said Burke, the first author."However, we found the proteins produced by these genes interact ina different way, based on ...New 'Twist' In Proteins Offers Possible Route To Improved Antibiotics
...ium Escherichia coli. The LpxA enzymecatalyzes the first step in synthesis of the lipid that makes up the o...tor, UDP-N-acetyl glucosamine,and functions as the first step of lipid A biosynthesis. Lipid A servesas the outermost coat of bacteria like E. coli. Thus, Lp...... subatomic particles. The process transmutes U-238 first into another uranium isotope, U-234, and then into an isotope of the element thorium, Th-230. Thorium, unlike uranium, does not dissolve in water. Therefore, scientists reason, all Th-230 found in limestone must be the product of radioactive decay of...Heat-loving Microbe Repairs Its DNA With Light
...crobial geneticists as "photoreactivation," is the first DNArepair process to be measured in a hyperthermop...he other hand, Grogansays it seems ironic that the first example of DNA repair to beobserved in S. acidocaldarius works on UV-induced DNA damage, andnot th...Children Become Gorillas In VR Zoo
...tionsdemonstrated what they believe is the world's first virtual realitygorilla exhibit. Local schoolchild... "Our Zoo Atlanta team of scientists and educators first began toplan a 'virtual zoo' three years ago," said Dr. Terry L. Maple, directorof the zoo and one o...From Corn Rootworms To Art, Cornell's Reactor Is At The Core
...ed pictures that X-rays cannot produce. It is the first time neutron radiography has been used to study insects. "X-rays pass through the rootworms without attenuation. Neutrons, however, are attenuated by the hydrogen in the rootworms," Davis said. "With a neutron beam, we can also see the corn roots a...Duke Researchers Show "Editing" Can Fix Faulty Genes In New Approach To Gene Therapy
...rsity Medical Center researchershave shown for the first time that enzymes can be used inside living cellst...ected version. To accomplishthis, he turned to the first ribozyme discovered, from the single-celledorganism Tetrahymena thermophila . This ribozyme not onl...Freshwater Sponges May Pose Threat To Zebra Mussels
...ome areas, eventually killing them. Researchers first noticed the increase in sponges in 1993 while studying an artificial reef built about 7 years ago near Lorain, Ohio by researchers from Ohio> Sea Grant. It's possible the increase is related to the zebra mussel invasion, which began in the late ...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
...94 issue of Nature Genetics,Marchuk identified the first gene linked to HHT. This gene, called ENG,is locat...ng blood vessels. "We realized when we found the first gene that some families werenot linked to this gene, meaning HHT really has several forms," Marchuks...Transgenic Rice Plants Resist Insects, Drought And Salt Damage
...sue of the journal Nature Biotechnology, marks the first time that useful genes were successfully transferr...r plant species that made the transgenic rice were first introduced to cells of three Japonica rice varieties with the Biolistic particle delivery system, th...Race Plus Roaches: A Breathtaking Link
...nal of Allergy and Clinical Immunology is also the first to report that children in the most infested homes are the most sensitive to the allergens, a clear indication of dose responsiveness, the researchers say. "We honestly don't know why race plays a role independent of poverty," says Peyton Egglesto...Mutate Or Die: New Polymerase Gives Desperate Yeast An Option
Biologists have discovered the first of a new DNA polymerase family: a last-gasp enzyme... The enzyme, dubbed "zeta," is a member of the first neweukaryotic DNA polymerase family to be discovered in about a decade and is the first polymerase w......ted stimulative effect, cantharidin was one of the first natural compounds to undergo scientific investigat...sfer to their mates at copulation. "We aren't the first to prospect for useful compounds," said CIRCE-founder Eisner, who advocates "chemical prospecting" t......different chemical signatures," said Kinkle. Sarbu first began exploring the Movile Cave in 1986 followingits discovery by Romanian geologist Cristian Lascu. Theexplorations halted after Sarbu fled the oppression of theCeausescu regime, resuming in 1990. The current research is funded by the National Scie...