UT Southwestern receives $1.78 million grant for obesity research as part of NIH Roadmap initiative
...o develop state-of-the-art research programs using genetically modified mice to elucidate the metabolic and molecular bases of obesity and metabolic syndromes; and to support translation of scientific findings made in animal models to humans. Dr. Keith Parker, chief of endocrinology and director of the Jean D. W...Chemical derived from vitamin-E shows early promise as cancer drug
...e. They result from studies involving treatment of genetically identical mice, which were given the novel vitamin... the animals because the cells had previously been genetically modified by co-author LuZhe Sun from the University of Texas Health Science Center in San Antonio to...Cancer vaccine based on pathogenic listeria bacteria shows promise targeting metastases
...tists at Cerus Corp. in Concord, Calif., employs a genetically engineered listeria bacteria based on a strain cre...or human trials. Cerus ultimately hopes to use the genetically engineered listeria vaccine to target cancers such as pancreatic and ovarian cancer, and possibly le...Hidden diversity: DNA 'barcoding' reveals a common butterfly is actually 10 different species
...this "species" is really an amalgam of a number of genetically distinct lineages, each with different caterpillar...t if that extinct animal was the only example of a genetically distinct species, hiding inside a morphology similar to the surviving species?" Janzen and his colle...DNA barcode finds four new bird species
...h of DNA -- a so-called DNA barcode -- can be used genetically to identify known species and to find new ones. "A uniform system to use DNA to identify all plants and animals would allow many more people -- from environmental regulators to nature lovers -- to identify organisms," says Mark Y. Stoeckle, M.D., g...Tracing genes, biologists show lizard migration is traced to Florida
...searchers have found that there are at least eight genetically distinct groups of the lizard. In the late 1800s, Anolis sagrei was introduced (probably through a shipment of goods) to the Florida Keys, got a toehold and, after a decades-long lag, began spreading into the Florida mainland in the 1940s, most like...'Smart antibiotics' may result from UCLA research
... potential for treating bacterial infections using genetically engineered phages that will efficiently overcome bacterial resistance." Bacteriophages evolve rapidly and are a "treasure-trove of fascinating biological mechanisms," Miller said. His research team studied a bacteriophage that was able to change t...Poplar DNA code cracked -- a step in combating global warming?
...etic knowledge enables researchers to modify trees genetically for the benefit of humankind and the environment. The genome sequence can contribute to strategies for improving trees more rapidly or for modifying them genetically. Today, trees are the earth's lungs - and, for example, they can be modified so tha...Scientists find nanowires capable of detecting individual viruses
... also to detect common strains as well as variants genetically engineered by would-be bioterrorists. By making an array sensitive to numerous domains of a given virus, the chances of even a modified virus escaping detection would be very low. In a clinical setting, the extreme sensitivity of nanowire arrays mean...Microbes eat their way to better concrete
...nding cycle, Bang and Ramakrishnan plan to develop genetically engineered microorganisms that can produce excess amounts of organic and inorganic biosealant. "This microbial sealant is a smart material that is environmentally safer and economically more feasible than the currently available synthetic sealing mat...Scientists discover potential new way to control drug-resistant bacteria
...lieve that this discovery could lead to the use of genetically engineered phages to treat bacterial infections that have become resistant to antibiotics. "This serendipitous finding underscores the importance of basic research," says Anthony S. Fauci, M.D., director of NIAID. "With our increased understandi...Study explores gene transfer to modify underlying course of Alzheimer's disease
... interpreted with extreme caution. This study used genetically modified skin cells to deliver the NGF. Results from that study were presented at the American Academy of Neurology meeting in Philadelphia this past April. The study being conducted at Rush uses a more sophisticated means of delivering NGF to the br...Scientists explore genome of methane-breathing microbe
...e in the genome. Such phages could be exploited to genetically manipulate M. capsulatus to more efficiently produce microbial protein for commercial animal feed. The study's senior author, TIGR Investigator Jonathan Eisen, says the analysis of M. capsulatus also will help scientists learn more about some methan...22nd amino acid synthesized and added to genetic code of e. coli bacteria
... community by announcing their discovery of a 22nd genetically encoded amino acid. Now they have capped that disc... translator enzymes so that new amino acids can be genetically programmed in cells to produce novel proteins for biotechnology," explained Joe Krzycki, a professor...Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
... The Plant Cell, scientists succeeded in producing genetically modified linseed plants that accumulate significan... and specific profiles of very long chain PUFAs in genetically modified oilseed crops. In addition to the possibility of providing healthier, more nutritious oils ...Information system to help scientists analyze mechanisms of social behavior
...at matters for social behavior is that DNA is both genetically inherited and environmentally responsive." BeeSpace was one of six awards totaling $30 million announced today (Sept. 16) as part of the NSF's Frontiers of Integrative Biological Research (FIBR), a program now in its second year. BeeSpace will be hou...USC study links historical increases in life span to lower childhood exposure to infection
...ted much earlier, Finch said. Children found to be genetically predisposed to heart disease, for example, could be treated starting at a much younger age. "These people would have a special lifestyle recommendation from the earliest years," Finch said. "We noticed that improvements in the environment ma...Joslin researchers clarify mechanisms for beta-cell formation
... studied this compensatory growth in two different genetically engineered animal models of insulin resistance called IR/IRS-1 mice and LIRKO mice. Dr. Kahn is the Mary K. Iacocca Professor of Medicine at Harvard Medical School. The results of immunohistochemical staining suggest that these new beta cells are ...Wiley publishes Welcome to the Genome: A User's Guide to the Genetic Past, Present, and Future
...ized medicine to international trade disputes over genetically modified foods, to the religious questions raised by then President Bill Clinton's appraisal of the Human Genome Project as the learning of "the language in which God created life." There is little doubt that we are in the midst of the Genomics Revo......e similar clinical and pathological traits but are genetically distinct. All NCL disorders cause progressive loss of motor skills, mental retardation, loss of speech, blindness, uncontrolled seizures and, eventually, premature death. The juvenile form of Batten disease, caused by mutations in the CLN3 gene, is t...