Structure Of Enzyme Involved In Gentamicin Resistance Revealed For First Time
...hat this narrow cleft acts as the binding site for gentamicin andholds it in place," says Burley. "When the acetyl group is transferred to theprotein, the gentamicin flies off. These findings open the door for the design of drugs that would inhibit theaction of AAT....A common antibiotic called gentamicin might be able to completely arrestdisease progress...ents with this particulartype of genetic mutation, gentamicin might well be an effective treatment," saysH. Lee Sweeney, PhD, chairman of the department of physio......ob." The antibiotics from the gentamicin family proved to be the most p... The mefloquine compounds enable the gentamicin to enter the bacterium and go to work," he said....