Missing genes may help explain why plague bacteria are so deadly
LIVERMORE, Calif. What makes the germ that causes plague so fearsomely lethal, while a close relative only produces digestive disorders and is rarely fatal? The answer may be in its genes or rather, its lack of them. By comparing the genome of the plague bacillus, Yersinia pestis, wit...Breaking new ground in germ cell guidance
...evelopment is the journey undertaken by primordial germ cells in the Drosophila embryo. These cells form e...onad, acquiring the characteristics of more mature germ cells en route. The puzzle of how these cells find their way through the developing body has challen...New genetic hypothesis for the cause of autism
...de novo defects (epigenetic or genetic) arising in germ cells or in the embryo prior to twinning They speculate that one or more additional genes whose function affects the role of UBE3A likely participate with the Angelman gene in an oligogenic inheritance model. The researchers reviewed available evide...One-hundred-fifty year old lessons of John Snow still relevant today
...ons nearly 30 years before Louis Pasteur work with germ theory. "It's interesting to note that Snow came to his conclusions before germ theory and that he didn't even use that concept," he said. "Indeed, he called the agents that caused...Review article makes case for a new source of cells in the body
...scle cells come from one of the body's three basic germ layers laid down early in development called the m..., the epithelium, comes from the endoderm, another germ layer. Now the science is showing that VENT cells contribute to all these tissues as well. Challeng...Joslin Diabetes Center launches research section on developmental and stem cell biology
...gulation of genes important for the development of germ cells, which form the sperm and egg, and the early...ucing cells. In addition, Dr. Blackwell's work on germ cells in C. elegans is already uncovering basic principles of germ cell self-renewal and function th...DFG presents the 2004 MAK and BAT value lists
...es are classified according to their carcinogenic, germ cell mutagenic, reproduction-endangering, sensitising or skin-absorptive effect. Compared to the previous year, there were 91 changes and new entries. This year, two metals that were classified as carcinogenic in humans deserve particular notice: bas...NRH1 and Wnt signaling come together in convergent extension
...n the separation of the embryo into three distinct germ layers, which go on to give rise to all of the tissues and structures in the adult animal's body. During this transformation, known as gastrulation, the embryo changes from a roughly spherical shape to an elongated, streamlined form through a process...Growing replacement teeth and dental tissues
...a Yelick and colleagues have seeded cultured tooth germ cells on biodegradable scaffolds which were then implanted to bioengineer tooth tissues, while in London (UK), Paul Sharpe's group has been able to generate tooth structures from non-dental mesenchymal cells placed in contact with embryonic oral epit...Researchers identify gene linked to sperm-producing stem cells in mammals
...e trying to do is unravel the mystery of the adult germ stem cells in male testicles, which are capable of... like red blood cells. In the adult testicles, the germ stem cells can produce more germ stem cells, but can also produce daughter cells that go on to becom...Jay Levy honored with 2004 Abbott Laboratories Award in Clinical and Diagnostic Immunology
...the virus was isolated. This finding confirmed the germ line transmission of viruses and led to a greater appreciation of the wide range of cellular hosts that could be infected by retroviruses. He and his group showed that HIV can become more virulent over time and can infect the brain, bowel, and severa...Laboratory rat gene sequencing completed
...arly two times more mutation in the brown rat male germ line than the female germ line, perhaps because there are more cell divisions along the path to making a sperm than the path t...Survey reports fall in stem cell transplants for breast cancer
...es. Seven other specific types of solid tumours germ cell cancer (12%), neuroblastoma (9%), Ewing's sar...table situation in glioma, soft tissue sarcoma and germ cell tumours and an increase followed by a decrease in breast, lung and ovarian cancer. For allogeni...MGH study finds female mammals produce egg cells into adulthood
... cells on the organs' outer surface that resembled germ cells, which are the source of oocytes that develo...ound to express a gene known to be present only in germ cells and were shown to maintain the ability to undergo cell division in juvenile and adult ovaries....Cancer rates in teens and early 20s rising
...-year-olds, particularly in lymphoma, melanoma and germ cell tumours, including testicular germ cell tumours. A news briefing at Teenage Cancer Trust's Third International Conference on Adolescen...Jefferson researchers uncover biochemical clues to how cells migrate in embryos
...th a biochemical pathway vital to the migration of germ cells in embryonic zebrafish. In all organisms, including humans, germ cells are stem cells that are destined to become either sperm or egg cells, and they must migrate fr...Immerge reports PERVs most infectious to human cells not part of germ-line DNA of mini-swine
...fectious for human cells are not components of the germ line DNA of miniature swine, as previously thought. This is a crucial discovery with regard to developing modes of eliminating these viruses from pigs being developed for clinical xenotransplantation. It suggests that lengthy breeding programs, which...Pacifying bacteria prevents lethal post-op infections
...specially after major surgery. In the bowel, this germ can be harmless, or it can turn deadly, causing gut-derived sepsis. "This is a disease of human progress," explains Alverdy. When people are severely ill "we put them in intensive care, where almost every thing we do alarms these bacterial passenger...Highlights of Tufts University nutrition research: January 2004
...lude beef, poultry, shellfish, beans, liver, wheat germ and prune juice. In addition to iron and calcium, the newsletter advises people not to forget the other bone building nutrients such as vitamin D and vitamin K, which are also part of a well-balanced diet. Loss of Familiar Fruits and Vegetables May......ene in every cell of their bodies, including their germ cells. This means the fish will transmit the foreign gene along to their offspring in a pattern identical to their natural genes. "Conventional techniques of producing transgenic animals, such as microinjection of genes into eggs and the retroviral ...