Bush nominates NJIT space explorer Louis Lanzerotti to NSF governing board
...visor to the President and the Congress, the Board initiates and conducts studies on a broad range of policy topics related to science and engineering research and education. ...Case for IBD combination therapy comes from research at Baylor, MIT and Hebrew University
...ell membrane phospholipids by phospholipase (PLA2) initiates production of inflammatory lipid mediators including arachidonic acid (AA)-derived eicosanoids, lysophospholipids and platelet-aggregating factor (PAF). Due to their role in IBD, eicosanoid suppression has been considered for treatment. However, inhi...New genetic research demonstrates possible cause of inherited form of Parkinson's disease
...ay pinpoint the mechanism by which the mutant gene initiates a cascade of events that causes this devastating neurological disease. "This discovery could aid in the development of new, targeted treatments to slow or stop the disease progression," said David Sulzer, Ph.D., professor of neurology and psychiatry...Researchers uncover secrets of immune system's munitions factory
... cells a clue to the nature of the machinery that initiates somatic hypermutation, and a topic for future studies in Alt's lab. Identifying RPA's involvement could have implications for understanding lymphomas. "Lymphomas and some mature B cell tumors are known to show aberrant somatic hypermutation and class...Synthesized molecules studied as weapon to stop cell division in cancer cells
...ust 22-26. Pin1 regulates the protein Cdc25, which initiates mitosis or cell division. Without Pin1, the cell enters programmed cell death -- which is good if it's a cancer cell. "It makes sense to inhibit the Pin1 enzyme," said Etzkorn. Protein shape determines biological function. Pin1 works by changing a ...Retroviral gene therapy? ASLV, HIV, and MLV show distinct target site preferences
...erted itself near a promoter region -- a site that initiates gene transcription -- of a proto-oncogene, a gene that can initiate cancer. Since viral vectors can integrate at various genomic locations, the safety and effectiveness of gene therapy ultimately depends on being able to predict a virus's particular ...Joslin Diabetes Center launches research section on developmental and stem cell biology
...is a gene-control circuit that in the early embryo initiates development of the digestive system, which includes the pancreas. This control mechanism later orchestrates one of the body's most important defenses against oxidative stress. Oxidative stress, or an excess of free radicals within the cell, is the ...Casanova or caveman: Scientists isolate nerve cells that choreograph male fly's courtship behavior
...a male fruit fly encounters a prospective mate, he initiates courtship by following her around and gently tapping her with his leg. If she seems interested, he serenades her with a love song. Singing is followed by more intimate acts that sometimes lead to successful mating. Now Stanford University scientists ...Plant respiration not just an evolutionary leftover, study shows
...rop plants so that the activity of the enzyme that initiates both the light-independent reactions of photosynthesis and photorespiration would favor photosynthesis to a greater extent and minimize photorespiration. The result, they have thought, would be more productive crop plants that make more efficient us...University of Chicago scientists pinpoint cellular cause of SIDS
...emakers in order to gasp, which wakes the baby and initiates movement or crying. "Gasping is an important arousal or auto-resuscitation mechanism," Ramirez says. It resets a baby's normal breathing rhythm and also alerts the baby as well as the mother that something is wrong. The Neuron paper shows that the br...Tracing a killer's path in Lou Gehrig's disease
...presents the common property of these mutants that initiates a cascade of damage," they wrote. In a second paper, Robert H. Brown, Jr., and his colleagues shed light on a specific mechanism by which the mutant SOD1 kills spinal cord neurons once it reaches their mitochondria. Brown and his colleagues discovere...Parting genomes: UA biologists discover seeds of speciation
...haven't been able to put their finger on just what initiates the reproductive isolation. Several researchers have identified mutant forms of certain genes associated with the inability of fruitflies to hybridize with closely related species, but in all cases those genes were discovered long after the two speci...Study in flies allows researchers to visualize formation of a memory
...searchers saw may be the all-important switch that initiates the formation of new memories. This research suggests a previously unknown mechanism for how memories are formed, Dr. Davis says. While this study looked only at learning related to odors, this newly identified process may be at work in many other...UNC researchers identify virus gene involved in tumor cell growth, spread
... in Kaposi's sarcoma-associated herpesvirus (KSHV) initiates these processes by causing cells to secrete growth and invasive factors. Since there is no cure for herpesviruses, the discovery of this gene's role in the growth and spread of the sarcoma raises the possibility that a treatment aimed at blocking K1...JCI table of contents, 2 April 2004
...roduces a receptor that, upon activation by TNF-_, initiates the Fas-induced apoptotic pathway. Treatment of two tumor mouse models resulted in tumor growth rate reduction and decreased tumor size. Histology revealed that EC apoptosis was largely responsible for the antitumor effects. Liver analysis further in...Fetal lungs provide a signal initiating labor, UT Southwestern researchers find
...eleased from the lungs of a developing mouse fetus initiates a cascade of chemical events leading to the mother...of a developing fetus contains the key signal that initiates labor. The substance, called surfactant, is essential for normal breathing outside the womb. "We fou......he enzyme, which is derived from horseradish root, initiates a reaction that makes conventional non-fluorescent colored dyes precipitate within the cell where the targeted genes are working. But only two colors at a time can be seen using this method, and thus only the activity of two genes. Furthermore, it is...UCSF finding advances insight into adult stem cells in human brain
... develop, scientists do not know where - or what - initiates the process of uncontrolled cell replication that leads to the formation of these brain tumors. Some evidence suggests, say the UCSF researchers, that the tumors may originate around the lining of the ventricles. "On occasion, we do have the oppor...Molecular mechanisms that trigger flowering in spring
...erved in the plant Kingdom and knowledge of how it initiates the formation of flowers in spring could help increase the yield of crop plants. Around 80 years ago, tobacco plants were shown to distinguish summer and winter by measuring the length of the day and night. This process, called photoperiodism, was la......sion of VIN3, which occurs after exposure to cold, initiates a series of changes in one of the flower-suppressing genes. Specifically, VIN3 activation permanently modifies the structure of histones, a group of proteins over which DNA is wrapped. These changes block the flower-suppressing gene, switching the pl...