Brain Protein "Rescues" Neurons From Atrophy
... was not known whether neurotrophins were, indeed, key substances that cause the brain to "wire" itself i...y to be mediated by such a factor," Katz said. The key to the scientists' discovery was a new technique of providing neurotrophins to brain cells that, for......ers. These dopamine-activated pleasure centers are key to theaddictive reinforcing pattern, even though addictive substances such asalcohol, nicotine, and cocaine may exert their influence on many differentareas of the brain, Caron said. Additional background: Insights into Parkinson's disease The res...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...features that allow it to fit parts of cABL like a key fits a lock. "This is the first time we've been able to open a window on what activates normal cABL," said Pendergast. "People have been looking for this molecule, or a molecule with these characteristics, for over a decade." In their experiments, Da...Key to Triplet Repeat Brain Diseases Open Door For New Way To Understand, Treat Genetic Diseases"
...y Medical Center researchers have found a possible key to braindisorders such as Huntington's disease, as... The interdisciplinary research under Roses was a key to the discovery, Vancesaid. "We are a group of clinicians, geneticists and molecular biologists.Onl...Duke Researchers Discover Candidate Susceptibility Gene For Autoimmune Disease
... they found they hadactually located what may be a key gene involved in autoimmune diseasessuch as arthritis and dermatitis. "This research is a perfect example of how research in one area canoften lead to an understanding in an apparently unrelated field," Blackshearsaid. "We were studying factors in...New Discovery About Genes Has Implications For Genetic Therapy
...n conveying genetic information -- may well be the key to determining where new information is transferred into a gene. If true, the finding has important implications for potential future use in guiding genetic therapy. Current techniques can insert new information into genes but exactly where that ...International Research Team Clones New Skin Cancer Gene
...ls under control. "Genetic mutation of PTC is the key step in development of skin cancer,2 said Allen Bale, M.D., senior author of the Cell paper and director of the Cancer Genetics Program at the Yale Cancer Center. The discovery paves the way for novel approaches to preventing and treating basal cell ......" A cell's suicidal tendencies maybe an organism's key weapon in the fight against cancer and autoimmune diseases:cells that wander too far from their source of molecular signals naturallyself-destruct. When the self-destruction mechanism is disrupted, though,cancerous tumors made up of rapidly reproduci...Nutrition Study Reshapes Strategies For Athletes
...many of the women heptathletes. The most important key to an athlete'ssuccess, said Houtkooper, is replacing fluids lost during practice andcompetition. She adds that this is especially critical in the hot and sultryenvirons of Atlanta during July. "They have been able to realize through the training pro...Core Spins Faster Than Earth, Scientists Find
...g-term, worldwideseismological records, which hold key data for measuring the innercore's rotation. Dr.Song and Dr. Richards were intrigued by preliminary results lastfall from a theoretical computer model simulating the dynamo thatcreates Earth's magnetic field. The model, created by Gary Glatzmaierof t...Photosystem I -- An Intermediate Step -- May Not Be Necessary For Plants
...working undetected, the researchers investigated a key protein in the PSI complex before and after the experiments. Owens was not able to detect the key PSI protein. Does this mean that PSI is not necessary for normal photosynthesis? Owens gives an em...Nitric Oxide May Hold Key To First Treatment For Deadly Form Of Malaria, Duke Scientists Report
...chanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan di... SNO gets in, it disables the bacteria by damaging key proteinsthe bacteria need to survive. While the bacteria are busy trying to repairthemselves, the ma...Nitric Oxide Found To Control Cells By Turning On Genes; Suggests New Role In Health And Disease
...chanism -- the attachmentof nitric oxide (NO) to a key portion of a protein called a thiol -- thatcan di... SNO gets in, it disables the bacteria by damaging key proteinsthe bacteria need to survive. While the bacteria are busy trying to repairthemselves, the ma...PET Project Helps Reduce Pollution Threat From Heavy Metals
...o install and relativelyinexpensive. There are two key components to the system. The first is a bedof oxide-coated sand which attracts and holds onto heavy metalsin the storm runoff. Lab-scale experiments demonstrated thespecial sand can dramatically reduce the concentrations ofpollutants such as lead, c...Component In Soy Products May Be Substitute For Estrogen Treatment
...sedbone-mineral density, providing evidence that a key compound in soy products-- isoflavones -- could be...hebone densities in the women's lumbar spines -- a key location for assessingosteoporosis, a common disorder of aging women that is marked by a progressive...New Software Provides Quick Analysis of ion-Channel Activity
...vity of the body's organs, including the brain, is key to understanding normal physiology. It also is critical to understanding various genetic diseases, including cystic fibrosis, as well as some neuromuscular disorders and some cardiac arrythmias. Now, biophysicists at the University at Buffalo have d...NCAR Scientists Trek To Africa For Biosphere-Atmosphere Chemistry Study
...overall chemical balance. "Measuring isoprene is a key to this experiment," says Klinger. On hand for the field work will be five NCAR scientists and technicians, along with four scientists from the University of Brazzaville and collaborators from Paul Sabatier University, the California Institute of Tec...North America Hit Hard By Asteroid Strike In Yucatan 65 Million Years Ago
...the use of hardyspores, the plants are regarded as key flora in colonizing the site of anatural disaster. Plants in parts of the world not downrange from the impact took a lesser hitfrom the corridor of incineration. For example, several ancient evergreen treesfound in North America before the impact, b...Study Examines How Mechanisms Evolve To Regulate Bee Development
...ion of labor among worker honey bees,which plays a key role in the ecological success of the species. This project, however, looked specifically at how juvenile hormone affectsthe behavior of the stockier, bigger-winged drones in an attempt to gaininsight into the evolution of the mechanisms involved in...Duke's Russian Laser Making Ultraviolet Light And Gamma Rays
...students and staff of the FELLaboratory as well as key contributions from the Budker Institute of NuclearPhysics, Stanford University and Argonne National Laboratory," Madeysaid....