Joslin researchers clarify mechanisms for beta-cell formation
...ions, including heart attacks, strokes, blindness, kidney failure, blood vessel damage and nerve damage. ...JCI table of contents September 15, 2004
...lls TITLE: The renal papilla is a niche for adult kidney stem cells AUTHOR CONTACT: Juan A. Oliver Columbia University, 630 West 168th St, New York, NY 10032, USA Phone: 212-305-6938; Fax: 212-305-3475; E-mail: jao7@columbia.edu View the PDF of this article at: https://www.the-jci.org/press/20921.pdf ...Human chromosome 5 final sequence analysis released to public
...,000 genes, including those implicated in forms of kidney disease, prostate and colorectal cancer, leukemia, hypertension, diabetes and atherosclerosis. The chromosome 19 sequence was published in the April 1, 2004, issue of Nature. "I am confident that the interesting features that we have identified from...Simian virus 40 not associated with non-Hodgkin lymphoma, study shows
...ed poliovirus vaccines, which were grown in monkey kidney tissue. Several groups have reported detection of SV40 in the tumor tissue of 15% to 43% of NHL patients, and the virus causes leukemia and lymphoma in laboratory rodents. However, other research groups did not detect SV40 in NHL tumors, and recent e......ogical component of organs and tissues such as the kidney and the lining of the gut, and mesenchyme forming all migratory cells, including metastatic cancer cells, as well providing support for the epithelium in various contexts. Despite (or perhaps because of) these differences, our anatomy contains countl...Blue marlin in gulf have high mercury levels, A&M study shows
... effects of mercury on living organisms range from kidney damage to reproductive failure and birth defects.The issue of elevated mercury content in seafood has received a great deal of public awareness in Gulf Coast states in recent years and several articles have focused on the possibility that oil and gas...Joslin Diabetes Center adds first affiliate in California at Irvine Medical Center
...ing heart attack, stroke, blindness, nerve damage, kidney failure and poor circulation. "There is an epidem...rest to people with diabetes, such as pancreas and kidney transplantation and orthopedic foot surgery. "We aspire to bring the best care to our patients and ...Adaptive changes in the genome may provide insight into the genetics of complex disease
...connection to diseases such ashigh blood pressure, kidney disease, susceptibility to infection, asthma,and Alzheimer's disease. He and colleagues used data from the Seattle SNPs project, led by Dr.Deborah Nickerson, a professor in the Department of Genome Sciences at UW,which is a large-scale study of genet...Diabodies act as guided missiles targeted to mammary tumor growth
... was concentrated in the mammary tumors and in the kidney where it was excreted from the body." Since diabodies are so much smaller than native antibodies, the genetically engineered protein is cleared much quicker from the body, Adams said. However, the affinity that the diabody has for its antigen target...Decreasing toxins in brains of Alzheimer's patients keep cognitive deficits at bay
...where body fluids accumulate before flowing to the kidney to be filtered and eventually eliminated in the urine. The shunt is put in once, drains continuously, and is cleaned out periodically by a neurologist. The eight patients still have their shunts and there are now almost 100 patients recruited into t...Sweet success in targeting sugar molecules to cells in living animals
... azido sugars were most concentrated in the heart, kidney and liver, with much lesser amounts in the brain and thymus. These findings indicate it may be able to apply this tagging technique to study the biology of other organs and to look for changes in organs that occur in diseases as cancer. According to ...Embryonic stem cell therapy shows steady benefits in rebuilding infarcted heart
...ayed in the heart, and didn't spread to the brain, kidney or liver. Microscopy showed that the stem cell-derived cardiomyocytes took on the distinctive striations indicating proper development of contractile apparatus. Stem cell-treated hearts also showed normal cardiac ultrastructure, in contrast to acellu...When is a mouse like a test tube?
... Azide-labeled cells also were found in the heart, kidney and liver, though not the brain, thymus or gut. They then repeated the experiment, but on the eighth day injected each mouse with a phosphine attached to a fluorescent molecule called FLAG. After only 90 minutes, the FLAG tag appeared on spleen cells...Joslin Diabetes Center launches research section on developmental and stem cell biology
...peripheral vascular disease, diabetic retinopathy, kidney disease, nerve damage and birth defects. Many of these complications involve damage to large or small blood vessels. Stem cells show promise repairing blood vessels, so researchers hope that they might be able to undo some of the long-term damage tha...U-M scientists find common virus in human prostate tissue
... system especially those who have just received a kidney transplant the virus can cause serious kidney and bladder disease. Now, new research by scientists at the University of Michigan Medical Scho...Iron can have negative side effects on people with kidney disease
... million Americans one in nine adults have chronic kidney disease, and most don't even know it.[1] Physicia... end-stage renal disease (ESRD), which occurs when kidney disease has progressed and about 90% of kidney function has been lost. While iron therapy is a commo...Scientists build on case connecting inflammatory disease and depression
...y is used to treat patients who suffer either from kidney cancer or melanoma with metastasis, or from viral infections such as hepatitis C and AIDS. "A few thousand cancer patients and several hundreds of thousands of hepatitis C patients are treated each year with immunotherapy," Dantzer said. Immunotherap......nes (insulin, cortisol and leptine)] and liver and kidney histopathology were investigated. Calcium balance ...protein diet were reported, particularly regarding kidney and liver health. After six months of the experiment, the body weight of rats fed the high protein ...Patients' cells from tumors, the immune system merged for customized cancer therapy
...ys of bolstering patients' immune response against kidney and breast cancer. In a paper published in the Ju...ntainment of tumor growth in late stage breast and kidney patients through application of customized vaccinations made from the patients' own tumor and immune...UCSD biologists discover cell's defense mechanism against class of disease-causing bacterial toxins
...ver, the skin infection impetigo, pneumonia, acute kidney inflammation, toxic shock syndrome, acute rheumati...ientists found the same basic responses in hamster kidney cells with and without one of the two genes. These cells were exposed to aerolysin, the pore-forming...