Leader in cancer treatment and prevention research honored
... first in cancer research to begin studying in the laboratory those basic chemical agents and nutrients with the...t to definitive, randomized controlled trials. His laboratory and clinical research has emphasized the chemoprevention and treatment of such pervasive and potenti...Landmark gene agreement announced by Samoan government and UC Berkeley for anti-AIDS drug Prostratin
... mamala tree bark and stemwood. Researchers in the laboratory of Jay Keasling, UC Berkeley professor of chemical engineering, plan to clone the genes from the tree that naturally produce Prostratin and insert them into bacteria to make microbial factories for Prostratin. A similar technology is currently being ...Landmark agreement between Samoa and UC Berkeley could help search for AIDS cure
...nd stemwood of the mamala tree. Researchers in the laboratory of Jay Keasling, UC Berkeley professor of chemical engineering, plan to clone the genes from the tree that naturally produce Prostratin and insert them into bacteria to make microbial factories for the drug. A similar technology is currently being ex...Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
...o how smoke affects genomic stability of cells. In laboratory studies using human fibroblasts, common cells found in connective tissue, William S. Saunders, Ph.D., and colleagues discovered that exposure to even a small amount of cigarette smoke condensate equal to about 1/25 of a cigarette caused breaks to b...DNA lends scientists a hand, revealing new chemical reactions
...imes lower than the concentrations of molecules in laboratory reactors. In nature, the reactions between these highly dilute molecules are directed by enzymes that selectively bring certain biological reactants together. Liu and his colleagues use DNA as a similar type of intermediary to bring together syntheti...Trial shows which brain cancer patients benefit from temozolomide
...could be carried out fairly easily in any genetics laboratory and takes only two to three days, although the ava...ction of faults in the DNA. Dr. Hegi, head of the laboratory of tumour biology and genetics at the Department of Neurosurgery, University Hospital of Lausanne, S...New Arizona State center brings science to policy on issues of water resources and urban growth
...er decisions. With the Valley, we have the perfect laboratory in which do to that." Redman added that inhabitants of the Phoenix area have dealt with water issues dating back to the ancient native Hohokam, who first settled in the Valley around 500 A.D. and built an enormous irrigation system to ...Researchers identify protein promoting vascular tumor growth
...her vascular tumors. Sen, director of the laboratory of molecular medicine in OSU's Heart and Lung Research Institute, said this research lays the foundation for clinical trials testing the effectiveness of both antibody-based therapies and, even sooner, an experimental nutritional intervention for vas...UCSF scientist Joe Derisi named MaCarthur Fellow
...Biological Sciences (PIBS) graduate student in the laboratory of former UCSF scientist Tim Mitchison. Theriot, a... In 1997, Eva Harris, PhD, formerly of the UCSF laboratory of Nina Agabian, PhD, in the UCSF Department of Stomatology, was named a MacArthur Fellow for her wo...UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies
...mistry, is the lead author of the paper. Overman's laboratory synthesized the small molecules; Robinson's laboratory tested them for cellular toxicity and anti-HIV activity; and Weiss' laboratory performed measurement...No role for simian virus 40 in human pleural mesotheliomas
...her groups. This has fueled an ongoing debate over laboratory methods and the strength of the association of SV4...but from SV40 DNA fragments engineered into common laboratory plasmid vectors used in molecular biology research. This source of SV40 DNA fragments may be unreco...Females may be more susceptible to overindulge 'sweet tooth' cravings than males
...ng greater fat or sugar than that found in regular laboratory chow. Because such diet-induced hyperphagia has been studied primarily in sedentary male rats, the researchers' goal was to investigate the effects of gender and exercise on caloric intake of a diet (chow supplemented with a supply of liquid sweetene...Brown research reveals key insight into memory-making
...nto the hippocampal neurons of rats, Kauer and her laboratory team found that AMPA receptors are indeed stored in recycling endosomes. When the neuron is stimulated, AMPA receptors leave this compartment and are rushed down the dendritic spine by three "chaperone" proteins Rab11a, Rme1, and Syn13. These additi...Cannabis may help combat cancer-causing herpes viruses
...ed, these same cells survived when cultured in the laboratory along with the cannabinoid compound further evidence that THC prevents viral reactivation. Furthermore, the researchers showed that THC acts specifically on gamma herpes viruses. The chemical had no effect on another related virus, herpes simplex-1...'Smart antibiotics' may result from UCLA research
...loit the new knowledge to generate proteins in the laboratory that will bind to almost any molecule of interest. "We think we can make proteins that bind to peptides, and make peptides that bind to larger proteins," he said. As is often the case in science, the project was initially undertaken for an u...Scientists find nanowires capable of detecting individual viruses
...iruses, most are laborious and appropriate only in laboratory settings. The use of nanowires provides immediate verification of a given virus's presence without any specialized biochemical manipulation. Lieber says nanowire arrays could be scaled up not only to detect many different viruses, but also to detect ...Grant advances biochemical engineering laboratory
...n to continue developing a biochemical engineering laboratory on campus. The laboratory will support Tech's chemical engineering focus area in biochemical engineering that prepares student...Scientists discover potential new way to control drug-resistant bacteria
...ed from this discovery to generate proteins in the laboratory that will bind to almost any molecule of interest. ...16th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics
... genetic predictive test can be carried out in any laboratory and means temozolomide can now become a targeted treatment. * Dr Ardeshir Ghavamzadeh: Trial results indicate arsenic should now be considered first-line treatment for one type of leukaemia *Dr Kim Chi: Successful results of Phase I trial of the firs......l. Dr. Laising Yen and other members of Mulligan's laboratory began by evaluating hundreds of known ribozymes, and found two that function well in human cells. One ribozyme was especially prone to cutting itself in two, and the researchers tweaked it to make it even more efficient. Next, they identified two c...