Cigarette smoke causes breaks in DNA and defects to a cell's chromosomes, Pitt study finds
...lity in cancer cells. Because cigarette smoking is linked to oral, larynx, lung, bladder and esophageal cancers, our results showing that cigarette smoke can produce anaphase bridges and destabilize a cell's chromosomes have added significance," said Dr. Saunders. "The failure of the cell to accurately repa...DNA lends scientists a hand, revealing new chemical reactions
...uct. Because the resulting synthetic compounds are linked to DNA, techniques long used to screen and amplify the genetic mainstay can be applied. In the current work, the scientists coupled DNA-templated synthesis with in vitro selection and DNA microarray analysis to scan for pairs of reactants that are ab...Alzheimer's disease is not accelerated aging
... the volume of two regions of the brain previously linked with age-associated changes: the corpus callosum, and the medial temporal lobe. Comparing volume in young adults, older adults without dementia, and individuals with mild dementia of the Alzheimer type, they found clear differences between the...New molecular link key to cellular proteins involved in cancer progression, other diseases
...Since Polycomb-group proteins have been previously linked to cancer, we anticipate that the ubiquitination of histone H2A will also be linked to some types of cancer," said Zhang. By dividing human cellular extract into smaller and smaller fr...Safety of isoflavones in dietary supplements targeted by Illinois initiative
...ves to hormone-replacement therapy, which has been linked to cardiovascular problems and dementia, for battling symptoms such as hot flashes. Initially, the researchers will focus on the biological effects of pure isoflavones, including genistein and equol. Next they will target the effects of complex ...Hidden diversity: DNA 'barcoding' reveals a common butterfly is actually 10 different species
...by slight variations in color, which then could be linked to the particular plants the caterpillars ate. It soon became obvious that A. fulgerator was, indeed, a complex of a number of separate species whose adult forms looked remarkably similar. When the centuries-old method of telling insects apart -- ...DNA barcode finds four new bird species
...ant aspect of the database is that each barcode is linked to an actual museum specimen. "Linking sequences to physical specimens makes the results believable, repeatable and open to revision," says Stoeckle. "Once you build a library, then many people can take advantage of it," adds Stoeckle. ...Brown research reveals key insight into memory-making
...l retardation and diseases such as Alzheimer's are linked to nerve cell dysfunction in the hippocampus. The new research provides new targets for drugs or other treatments for these conditions. Esther Penick and Jeffrey Edwards, postdoctoral research fellows in Kauer's lab, worked on the study as did Mikyou...Certain genes boost fish oils' protection against breast cancer
...ils, called marine n-3 or omega-3 fatty acids, are linked to the cancer-fighting properties of the oil's byproducts, propose investigators from the Keck School of Medicine of the University of Southern California and the National University of Singapore. The study in Carcinogenesis was published early onlin...Key stimulator of colorectal cancer identified
...PARd), a regulator of cell survival, has also been linked to CRC. Dr. Raymond N. DuBois from the Department of Medicine at Vanderbilt University Medical Center and Vanderbilt-Ingram Cancer Center in Nashville, Tennessee and colleagues investigated whether the ability of PGE2 to promote CRC is dependent on P...Research suggests new avenue for stopping, preventing colon cancer
...em, prostaglandin E2 (PGE2), has been specifically linked to the development of colon polyps.The current stu...igh-dose use of the COX-2 inhibitor Vioxx has been linked to high blood pressure and an increased risk of serious heart problems in some patients. Last month...Students build submarine to track Octopuses
...ntly the sub and a computer on the mother boat are linked by a 100-foot-long coaxial cable. "We want to get rid of that tether from the boat and have it come to the surface at a buoy," Vincent said. "Then there will be a wireless link between the buoy and the boat." The team also will modify Shadow's buoyan...Genetic modification of linseed produces healthier omega 3 and 6 fatty acids
...f all living organisms. Fatty acid chains that are linked by single bonds between carbon atoms are said to b...in PUFA such as those found in fish oils, has been linked to a decreased risk of heart disease, and also to a variety of other health benefits, including prot...Tips from the Journals of the American Society for Microbiology
...edients are known for their antimicrobial activity linked to the phenolic moiety and therefore are suitable as antimicrobial natural extracts when effectively combined with lactic acid," say the researchers. (Y.T. Lin, R.G. Labbe, K. Shetty. 2004. Inhibition of Listeria monocyto...Human chromosome 5 final sequence analysis released to public
...d by chromosome 5 genes, but they haven't yet been linked to a specific gene. Other chromosome 5 genes include a cluster that codes for interleukins, molecules that are involved in immune signalling and maturation and are also implicated in asthma. The spaces between the genes are as important as the genes ...European common frog found to use novel mating strategy
...hes. What they uncovered was a strategy apparently linked to the unusually skewed operational sex ratio in the Pyrenean ponds, that is, the ratio of eager males to available females. For every female frog there were between four and 10 male frogs in a pond about half the size of an Olympic-size swimming poo...A liking for sweets, combined with novelty seeking, may predict alcoholism
Previous research has linked a pleasurable response to sweet taste (sweet liking) with a genetic vulnerability to alcoholism among children of alcoholic fathers. Sweet liking, however, is insufficient by itself to predict alcoholism. New research shows that the combination of sw......ll intestine. Development of this disease has been linked to the transformation of normal immune cells, call...activated by stress-induced chemicals and has been linked to tissue damage. The researchers found that the immune stimulator IL15 induces a series of biochemi...Protein is key for digestive function of the pancreas
...h is needed to establish whether VAMP8 is directly linked to pancreatitis.......ng two isoenzymes, MAO A and MAO B, that have been linked to violent criminal behavior and Parkinson's disease. The MAO A/B knockout mouse should provide an excellent model in which to address the specific roles of these neurotransmitters and their receptors in anxiety and stress-related disorders. The rese...