Hunt For Early Heart Attack Genes Begins
...he study will beoffered free blood cholesterol and lipoprotein analysis and information aboutmodifying their risks of having a heart attack. Participants will not need to come to the university for the study. Thescientists will make arrangements to receive patient's medical histories andhave samples o...New "Wonder Peanut" Beats Olive Oil In Healthful Benefits
...nt reductions in serum cholesterol and low density lipoprotein (LDL) cholesterol - the "bad" cholesterol. As reported in the July 1997 issue of the scientific journal Lipids, the study concluded that substituting high-oleic peanuts as the primary source of monounsaturated fatty acids as part of a low-fat diet ma...Hormonal Changes At Puberty Can Mask High Cholesterol In Blood
...ntion group hadsignificant declines in low-density lipoprotein (LDL) cholesterol, the "bad"cholesterol that leads to blockages in the blood vessels. However, LDL alsodeclined in the usual care group, so that the overall difference between thegroups was not as great as expected, reports Kwiterovich. The researche...Triglyceride Blood Levels Predict Heart Attack
...lycerol that bind to proteins and form low-density lipoprotein (LDL) andvery-low-density lipoprotein (VLDL). LDL and VLDL contain large amounts ofcholesterol and triglycerides that can adhere to the a..."Genetic Factors Influencing Cholesterol Response To Diet"
...an in those with apoE3. Other less common lipoprotein gene variants also have been shown toinfluence the...60;0.05). Inaddition, change in apoB (a measure of lipoprotein particle number) was linkedto the MnSOD locus (p<0.03). These data indicate that genet...Genetics Of Obesity And Of The Response To Chronic Overfeeding
... composition, fat distribution, insulin and plasma lipoprotein levels wasalso quite apparent. These results strongly suggest that undefined geneticfactors are associated with individual differences in the response to long termoverfeeding. These observations and others from the genetic epidemiologyliterature str...Induced Mutant Mouse Models Of Lipoprotein Disorders And Atherosclerosis
...disorders and atherosclerosis. Although the mouse lipoprotein pattern isdissimilar from that of the human, through induced mutations all of the abnormallipoprotein phenotypes in humans that are associated with atherosclerosissusceptibility have been produced in the mouse. This has provided insights int......tty acids, fish oils, andvitamins, not only on the lipoprotein profile but on atherosclerosis itself,"Breslow added. "Genes, Vitamins, Homocyst(e)ine and Cardiovascular Diseases" will be thesymposium topic of Malinow, a scientist at the Oregon Regional Primate ResearchCenter, Beaverton, and professor of med...Sex Differences In Heart Disease May Be Due To Enzyme That Breaks Down Fat
... alcohol and some cholesterol into verylow-density lipoprotein (VLDL), the largest type of lipoprotein. VLDL ist...nd very heroic, but that's therole of high-density lipoprotein (HDL), the so-called "good" cholesterol. HDLclears fragments of proteins, fats and cholesterol fro...Genetic Make-Up May Determine Response To Cholesterol-Lowering Drugs
... DNA studies to identify variations in thegene for lipoprotein lipase, an enzyme that plays a role in cholesterolmetabolism. Other scientists have found the lipoprotein lipase gene is tied toelevated cholesterol, insulin resistance, and severity of coronary arterydisea......an those exposed to apoE4 or no apoE. "So lipoprotein particles that may mimic those secreted by astrocytes inthe brain have different effects on neuronal structure according to whether theycontain apoE3 or apoE4," Holtzman says. "One could speculate that such an effecton structural plasticity might pro...Gene Detected That Decreases "Bad" LDL Cholesterol In Men May Cut Heart Disease Risk By 50 Percent
...esultsin an altered production of very-low-density lipoprotein (VLDL), aprotein-coated fat that is necessary to make LDL. The findings may have important implications in the field of drugdevelopment. Most drugs that treat high cholesterol work by removing excessamounts. However, the MTP variant helps ...After The Wine Is Made, The Rest Of The Grape May Be Good For You
...icantly retardedthe oxidation of human low-density lipoprotein (LDL) or bad cholesterol. Dietary antioxidants that protect LDL from oxidation may play a role inpreventing coronary heart disease, Meyer says. Over 4 million tons of grape pomace are produced annually, but it is currentlyused as a cattle feed, a soi...Obesity Gene: Possible Link To Heart Disease Risk
...od pressure, low levels of the "good" high-density lipoprotein cholesteroland elevations in insulin -- sets the stage for heart disease. Insulin is ahormone that helps the body use glucose, its main fuel. An excess of insulin (acondition called insulin resistance) indicates the body is not processingglucose no...New Alzheimer's-Associated Mutation May Provide Key To Disease Process
... with anerve cell receptor called LRP (low-density lipoprotein receptor-relatedprotein). Two important clues led Tanzi and his colleagues to examine whethermutations in A2M might be associated with Alzheimer's risk. First, two proteinsknown to be involved with Alzheimer's -- the amyloid precursor protein and ap...High Density Lipoproteins And Coronary Heart Disease
...view the hypothesis that lowlevels of high-density lipoprotein (HDL) cholesterol are a risk for coronaryheart disease; discuss metabolic disorders that result in this condition; andevaluate treatment options. The symposium, accredited by Continuing Medical Education at The Johns HopkinsUniversity School of Med...Wake Forest Physicians Demonstrate How Gene-Diet Interaction Affects Cholesterol Absorption
...lincreased 22 points in three weeks, a low density lipoprotein (LDL, the badcholesterol), increased by 19 points. In contrast, cholesterol increased by only5 points, and LDL by only 2 points in students with the variant gene. Weinberg said the variant gene affects dietary responsiveness byaltering the ...Nuts And Oats May Build A Strong Heart
...g/dL. The individuals' bloodlevels of low-density lipoprotein cholesterol (LDL or "bad" cholesterol) --which can accumulate in blood vessels, increasing risk of a heart attack orstroke -- followed the same pattern: The oat group's LDL was 23 mg/dL lower andthe wheat group's LDL was 8 mg/dL lower. Also, the peo...Gene Influences How Lifestyle Affects Blood Cholesterol
...e found to have low bloodlevels of the low-density lipoprotein (LDL), the so-called "bad" cholesterolthat promotes atherosclerosis, and high levels of high-density lipoprotein(HDL), called the "good" cholesterol because it helps remove LDL from the blood. People with low LDL levels and high HDL levels are at low...Vitamin E Supplement Decreases Autoantibodies To Oxidized LDL
... indicative of the harmfuloxidation of low-density lipoprotein (LDL), a precursor to artery-cloggingatherosclerosis. The team, led by Emory University's Sampath Parthasarathy,Ph.D., also reports that levels of such autoantibodies "might serve as an indicator forthe efficacy of antioxidants to attenuate oxidatio...