Scientists reinvent DNA as template to produce organic molecules
...sing modern synthetic chemistry, and yet this very modest set of protein and nucleic acid building blocks has given rise to the incredible complexity and diversity of living systems," says David R. Liu, associate professor of chemistry and chemical biology at Harvard. "We're interested in marrying fundament...Technology already exists to stabilize global warming
...olve improving energy conservation faster than the modest improvements that are continually occurring. The researchers identify various renewable energy sources, including solar and wind, that could be scaled up faster than current projections. Changes in forestry and farming techniques also could lead to s...Rutgers cancer prevention expert calls for FDA action to reduce colon cancer and osteoporosis
...ver time and an overall improvement in health at a modest financial cost and with minor modification of existing technology," the paper concludes. Newmark is an adjunct professor-in-residence at the Susan Lehman Cullman Laboratory for Cancer Research (Ernest Mario School of Pharmacy) of Rutgers, ......de it prohibitive. The costs are likely to be more modest and, most importantly, the simplicity of HDA makes it suitable for the development of hand-held DNA diagnostic devices that could be used to detect pathogens at the point-of-care or in the field....Report outlines steps needed to lessen smallpox threat
... study of poxviruses. "Poxvirology is a relatively modest field at the moment," said Harrison. "It is not a field that has attracted many energetic young investigators recently, and for obvious reasons. But, in fact, we realized that poxviruses could be used as interesting tools to answer questions, not onl...Anti-cancer agent built from anti-inflammatory drug
...se-2 (COX-2). But they couldn't explain the drug's modest anti-cancer activity. Past work led by Chen provided the answer. "We found that celecoxib's ability to cause cell death and to control inflammation were two different pharmacological properties, and that the two properties could be separated," Chen ...Digital evolution reveals the many ways to get to diversity
...ort fewer species than environments that have more modest productivity, a surprising pattern that is also seen in the digital world. The research seeks to answer questions of evolution that are a piece of the puzzle of understanding ecology. "The better we understand how our world came about, we can begin t...Calcium supplements associated with decreased risk of large bowel polyps
...necessary, and perhaps that high dietary fiber and modest dietary fat are required to optimize this [anticancer] effect. Additional data regarding nutrient interactions with calcium will help further refine optimum cancer protective strategies and may clarify the mechanisms by which calcium has its effects ...Study investigates breast cancer resistance to tamoxifen and possible way to reverse it
... inhibitors like gefitinib may have little or only modest benefits on ER-positive, HER2-overexpressing breast cancer, but the results do provide a strong rationale for combining tamoxifen with gefitinib or other EGFR/HER2 pathway inhibitors to overcome resistance in such tumors. Clinical trials of this new...Obesity and hypertension: Two epidemics or one?
...n in BP that is independent of sodium intake. Even modest weight loss of 510 percent of body weight is assoc...term use in weight loss and weight management. The modest efficacy of both drugs in short-term weight loss and long-term weight maintenance has been documente...Researchers identify two potential protein targets for new drug therapies for pancreatic cancer
...istant stroma. In the stromal tissue, there was a modest correlation between overexpression of FAK and FAP. This suggests that interaction between these proteins may contribute to the ability of pancreatic cancer to metastasize. "Due to the heterogeneity of the patient samples, we did not see a clear i...When combining new oral anti-cancer agents with standard chemotherapy, timing may be crucial
...sequentially with docetaxel. But PS-341 had only a modest effect when delivered alone -- and no effect when delivered simultaneously with docetaxel. "We've been delivering these drugs the same way we've delivered chemotherapy, assuming that the more we can give, and the longer we can give it, the better," G...Breastfeeding decreases infant mortality
... These data show that, even in the US, there is a modest decrease in mortality for breastfed children."...U.S. President's budget proposal means 5-year cuts 'well below historic levels'
...five years, NIH's $27 billion portfolio will see a modest rise due to increases in biodefense research. But ...deficit reduction targets, even agencies receiving modest increases like NIH and NSF will see their R&D funding fall beginning in FY 2006," Koizumi said. Di...Moderate iron deficiency affects cognitive performance - but iron supplementation improves it
... of Dr. John Beard, says the study shows that even modest levels of iron deficiency have a negative impact on cognitive functioning in young women. She says the study also is the first to demonstrate how iron supplementation can reverse this impact in this age group. Baseline cognition testing, looking at...... of crucial important for poverty reduction but is modest in size relative to the income of the rich countries, within the international target of 0.7 percent of rich-world GNP in official development assistance. 2. Both rich and poor countries must heed the lessons of science and foster the benefits of und......h the antibody we have studied so far has had only modest results to date, we are making some modifications to our existing antibodies to improve the molecule's ability to block FAP's action. Much more research lies ahead."...Research on inherited eye disorders uncovers new information about blood-vessel formation
...er and with a range of severity all the way from a modest abnormality of vasculature that does not impair vision at all to a severity of scarring that eliminates vision completely," said Nathans. FEVR is known to arise from defects in a gene known as Frizzled-4 , which codes for a protein receptor (Fz4). A...As obesity skyrockets, Joslin Diabetes Center urges action to stem the tide of type 2 diabetes
...esearch at Joslin and elsewhere showed that losing modest amounts of weight say, 10 pounds and walking 30 minutes daily reduced risk of developing type 2 diabetes by 58 percent among adults at risk. "However," Dr. Kahn continued, "I believe we can accelerate our efforts to decrease obesity and type ...A shrinking sink? Carbon fertilization may be flimsy weapon against warming
... carbon dioxide fertilization is likely to be more modest does not imply that carbon management through planting trees is a bad idea," Field explained. "Planting trees is a great idea. It's just that the trees will grow at their 'normal' rates or slightly faster, rather than at supercharged rates." Field co...