Tag: "morphine" at biology news
Peptides Implicated In Body's Response To Pain
...lt in acombination of neurokinin A antagonists and morphine
for the treatment ofmoderate to intense pain. Suc... fewer side effects andwould enable lower doses of morphine
to be used," said Dr. Basbaum. The NINDS, one of the National Institutes of Health located in Bethes...
Scientist Fancies Frogs For Pain Research
...lp humans betterunderstand how powerful drugs like morphine
and codeine affect the brain. Dr. Stevens, an asso...ch shows there is much similarity in the actionsof morphine
and other opioid drugs in amphibians and mammals." Dr. Stevens' lab is located in Tulsa, Oklahoma an...
U.S. In The Midst Of A Heroin Epidemic, But Many Overdose Deaths Can Be Prevented
...dramatic activity of heroin in thebody compared to morphine
and other opiates," he says. "Heroin is more solublein the fat cells so it crosses the blood-brain barrier within 15-20 seconds,rapidly achieving a high level in the brain and central nervous system, whichaccounts for both the 'rush' experienced by ...
Good news for "wusses": Research links pain sensitivity to gene
...e differences peopleexperience in pain relief from morphine
or morphine-like drugs. The work should eventually result in pain drugs tailored to a person'sindividual genetic sensitivities -- a hallmark of genome-based therapy. It alsocould offer the ability to predict a person's risk of addiction to o...
New treatment may relieve chronic pain, as reported in the 19 November issue of Science
... shouldn't cause the side effects of drugs such as morphine
or the complications of surgery. The study appears...t it doesn't interfere with the mechanism by which morphine
works. Physicians who wanted to administer this type of treatment to their patients should therefore...
Engineered mice point to new target for pain relief
...uld lead to the development of new drugs that make morphine
last longer and relieve pain at lower doses. The researchers report in the Dec. 24 Science that morphine
prevents pain longer and more completely when administered to mice engineered to lack a protein swit...
Pain drug reveals what most already know - men's and women's brains are simply different
... limitations. "A lot of people don't want to go on morphine
because it is addictive," saysFields. "What if ka...thclinical studies showing that women require less morphine
for post-operativepain than men. Fields' finding -- that specific brain regions in male and female r...
Welch Award honors 2 for unlocking nature's secrets
...ng penicillin and anti-tumor agents, Dr. Battersby morphine
and alkaloids for treatment of childhood leukemia. Organisms make substances like these through a series of reactions, each catalyzed by a specific enzyme. It was the development of a new technique in the late 1960s that first allowed scientists to b...
UCSF finding could lead to long-sought alternative to morphine
... have suggested that women prefer kappa-opioids to morphine
during labor and delivery, but current clinical wisdom dictates that they are ineffective, and the pharmaceutical industry's assessment of their effectiveness has been lukewarm at best. During the last five years, UCSF researchers have revealed a mo...
UPenn protein study
... cocaine was increased, although their response to morphine
was reduced, Yang said. Even more significantly, when the mice were administered drugs from the series of anti-depressants known as catecholamine reuptake inhibitors (desipramine, and reboxetine), "they didn't respond at all," she said. "We don't hav...
Heroin users' mystery a hope for back pain sufferers
... Former users of heroin,methadone, even long-term morphine
users can develop a "hypersensitivity" topain, causing enormous problems for their quality of life. Those who sufferfrom this condition are often not helped by any available treatment for acuteand chronic pain. And in another mystery, not all kinds...
Chemist at University of California, San Diego, wins national award for drug research
... need for treatment of chronic pain. Opium-derived morphine
is the current standard, but it can inhibit digestion and breathing as well as cause problems with addiction and the need for ever-increasing doses, called tolerance. Were interested in taking natures opioids, such as endorphins, and trying to make t...
Probing the role of the delta opioid receptor in alcohol consumption
...tes are drugs derived from opium - like heroin and morphine
- that act like chemicals the brain produces naturally, called endogenous (from within) opioids, which stimulate pleasurable feelings and suppress pain. Medications known as opiate antagonists bind with the brain's receptors for endogenous opioids, ...
Morphine-like drugs could offer relief for amputees
...searchers observed that the powerful pain reliever morphine
significantly relieved both stump and phantom pain...ar and significantly higher for both lidocaine and morphine
compared to placebo, which did not significantly reduce either type of pain....
Researchers find gene involved in pain relief
...proaches to pain management focus on drugs such as morphine
that stimulate cell receptors for the endorphin fa...ntage over the potentially addictive drugs such as morphine
that act on opioid receptors. "Pain is a huge, silent public health crisis that is only beginning to...
Nature's own antidote to cocaine
... stress. Addictive opiates, which include heroin, morphine
and other analgesics such as codeine, are structurally similar to the opioids produced naturally in the body and thus bind to and stimulate the same receptors, subsequently triggering these drugs' well-known effects. Cocaine, on the other hand, acts ...
Implantable pain pumps improve cancer patients' quality of life
...n and pancreatic cancers whose pain broke through morphine
or other opiate drugs; six were treated at Hopkins. Patients were randomly assigned to either receive an implantable pump delivering medications directly into the spinal fluid or to continue taking pain medicine by mouth. Results of the study, prese...
Anti-inflammatory drug reduces growth of cancerous tumors In rats
... have already tested other pain relievers, such as morphine
and fentanyl, and shown that they provide some protection against the tumor-promoting effects of surgery, but these drugs are pain relievers without anti-inflammatory action," Page says. "So we chose to test indomethacin because it eases both pain an...
Opioid medications a good bet for shingles-related pain
Despite worries over side effects, morphine
and other opiates appear to be effective in treating shingles-related nerve pain in older adults, a study at Johns Hopkins suggests. Caused by the same herpes zoster virus that causes chicken pox, shingles and its bouts of painful rashes on the body...
International functional genomics study looks for genes that cause drug tolerance and dependence
...ndent on them. The next step will be to administer morphine
to both groups of mice. This will show which genes in the mutant mouse are not affected by the drug, indicating which genes play a role in the body's ability to build tolerance or dependence, or both, on drugs like morphine. "Morphine is nothing...