Gene Knockout Prolongs Ovarian Lifespan In Mice
...eselectively blocking the gene's expression in the ovary alone, something thatcurrently is impossible. The study was led by Gloria Perez, DVM, PhD, and Rodolfo Robles, MD, both of theMGH Vincent Center for Reproductive Biology. In addition to Tilly andKorsmeyer, the study's other co-authors are Michael K...The genetics of aging: New study says cell division errors may be the common link
...OX-2, a key enzyme necessary for kidney, heart and ovary function. Altered expression of these genes may contribute to age-related breast cancer, neurodegenerative disease, arthritis and defects in other tissues such as kidney, heart and ovaries with advancing age. This is not the first time that Dr. Lerne...Researchers decipher fundamental signal for maleness
...terus, but are sterile due to lack of a functional ovary or testis. Weiss and his colleagues used nuclear magnetic resonance technology to reveal the three-dimensional structure of the protein. They found a new kind of DNA binding structure (containing intertwined zinc binding sites) that regulates genes,...Dairy scientist advances field of transgenics and knowledge of growth hormones
...important new knowledge concerning the role of the ovary and ovarian hormones in regulation of mammary deve...lt, he also discovered that the involvement of the ovary in regulation of peripubertal mammary development is different in cattle than in sheep. And while bo...Treatment protects mouse ovaries from radiation therapy
...earchers injected S1P into the sac surrounding one ovary in each mouse. Two weeks later, the ovaries receiving S1P appeared healthy, with a quantity of normal-appearing follicles - the tiny sacs in which egg cells grow - that was similar to that seen in non-irradiated mice, while the unprotected ovaries s...Scientists discover gene required for testis development
... Mutations in Dmrt1 do not adversely affect female ovary development. In addition to lending insight into the basis of human testis dysgenesis syndrome, Raymond's finding has surprising evolutionary implications. Proteins similar to Dmrt1 are known to be involved in male sexual development in insects an...Defining a niche that regulates stem cells
...embryonic germline stem cells - those cells in the ovary that are the earliest precursors to eggs. Accordin...matic cells to become stem cells. The Drosophila ovary represents a useful model system for studying the role of the niche in stem cell regulation, said Sp...More help for infertile women with polycystic ovary syndrome
...hope for women who are infertile due to polycystic ovary syndrome (PCOS). A study published in the February... the pituitary gland and the ovary. "Normally, the ovary and pituitary glands talk to each other," explains Ratts. "We think that insulin interferes with the...Biting may drive division of labor among social wasp workers
...cipients. "This does not seem to be related to ovary development or body size so this behavior does not seem to be connected to reproductive status," he said. "We don't know what drives biting behavior. There is a possibility that it might be genetic, or it could be chemical because we do know that s...Scientists report the first live births in large mammals after using frozen ovarian tissue
... to function." Prof Salle and his team removed one ovary from each ewe, cut it in half and froze each piece down to 1960C. They were then stored in liquid nitrogen for between one and three months. He said: "The hemi ovarian autografts could be stored for longer if necessary." When they were ready to gra...Discovery of follicles offers hope of babies for Turners syndrome girls
...54,000 follicles in the cortex of the whole of the ovary Mr Hreinsson said: "Our results show a rapid decline of follicular density between the age of 12 years and 19 years in the subjects we studied. In view of the limited number of subjects in our study, further research is needed to confirm our results...A pill for reversible suppression of periods - a new option
...ularly menstruates and the mechanism in the brain, ovary and uterus controlling their periods is identical to that of humans. According to Dr Brenner, senior scientist with the Oregon Center, the results should therefore be directly applicable to women. He said: "A reliable means of menstrual suppression w...Flower chemicals attract some insects but deter others with toxic warning
...the compounds were particularly prevalent in plant ovary walls -- making up as much as one fifth by dry weight -- as well as in other reproductive structures such as the anthers. "Just as important as attracting pollinators to a plant is producing viable seed, so there is an evolutionary incentive to prote...Fly cells on the move may reveal clues to cancer metastases
...allows a group of normally stationary cells in the ovary to travel, they report in the current issue of Cel...etics, understanding the signals that mobilize the ovary cells may help clarify how human cancer cells invade distant tissues, says Denise Montell, Ph.D., as...Differences between boys and girls show less than three weeks into pregnancy
...corpus luteum a temporary structure formed in the ovary after an egg is shed that produces oestrogen and progesterone until the placenta can take over their production. "Other research has already shown that MSHCG is significantly higher in the presence of a female fetus in the second and third trimesters...Making plants better lovers: Scientists find gene responsible for reproductive success in plants
...of extending a long tube up the style, through the ovary and into the ovule. Once in the ovule, the pollen tube tip bursts and releases the sperm that will fertilize the female egg. However, because many pollen tubes grow towards only a few ovules, the process of pollen tube elongation becomes a race for r...Mating molds provide new insights into speciation and human reproduction
...s oogenesis in women - a biological process in the ovary that results in the formation of eggs. "Human oogenesis is, at first glance, a bizarre process," Metzenberg wrote in Cell, noting that, at birth, a girl already will have developed some seven million egg cells that are "frozen" in an early stage of m......ested the survival capabilities of Chinese hamster ovary A10 cells by exposing them to alcohol, genotoxicants (substances that can damage DNA through mutation or cancer), and non-DNA reactive cytotoxic agents. A10 cells were chosen because they have been engineered to express alcohol dehydrogenase (ADH), ......air mutant cell lines derived from Chinese hamster ovary cells. Other researchers had demonstrated the ability of human L1s to repair DNA breaks in yeast cells, but Morrish is the first to show the effect can occur in mammalian cells. Since DNA damage may lead to cell death unless it is repaired, the exist...