Award winning researchers reveal potential new role for Glivec
...ity that it may not have been a true DFSP, but our patient without the translocation did not respond to imatinib. Nevertheless, our data support the use of imatinib where t(17-22) is detected, although our findings cannot be used to make any definite statements about tumours with other molecular abnormalitie...Trial shows which brain cancer patients benefit from temozolomide
...ication of cancer cells. So, it is bad news if the patient has non-methylated status because the DNA in these...d trial to test MGMT methylation status in a large patient population. "The test will provide the opportunity to select patients that might profit from temozol...High resolution satellite imagery assists hunt for infectious 'kissing bugs'
...ive, the bugs have to be eradicated to avoid rapid patient re-infection. As part of a wider anti-Chagas campaign in the area, Mdecins Sans Frontires workers oversee a methodical house-to-house inspection campaign, identifying where cracks need to be filled in and control methods such as spraying are required...16th EORTC NCI AACR Symposium 'Molecular Targets and Cancer Therapeutics'
...ore) killing them. Successful mouse study leads to patient trial. * Professor Eric Van Cutsem: International trial results shows way to measure success of centuximab (Erbitux). Randomised study now under way Chairman: Professor Jaap Verweij (EORTC chairman of conference scientific committee) together with sc...Study explores gene transfer to modify underlying course of Alzheimer's disease
...e stage, will be enrolled in the study. The first patient in the study was treated on July 27. Dr. David Bennett and Dr. Zoe Arvanitakis of the Rush Alzheimer's Disease Center are the co-principal investigators. Bennett is director of the center. Ceregene, Inc., based in San Diego, (a minority owned subsidi...Experimental drug shown to block mutant protein causing blood disease
...The researchers also tested the drug, PKC412, in a patient with the hard-to-treat disease, called Myeloproliferative Disease (MPD), and saw her symptoms improve. PKC412, like the spotlight drug Gleevec, is a highly specific "targeted" drug that disables a switch in cancer cells that has become jammed in the ...Yale digital diagnostic technology is basis of new company, HistoRx Inc.
...r pharmaceutical research and development, and for patient care." He said that HistoRx recently entered into feasibility studies with two major pharmaceutical companies and is scheduled to ship its first systems to two preeminent research universities this week. According to Rimm, "AQUA is completely...Brain has center for detecting sound motion
...their location. That's exactly the experience of a patient reported by Christine Ducommun and her colleagues, who used studies of the patient to demonstrate conclusively for the first time that the brain has a specialized region for processin...Protein is key to fatal disorder and normal cell function
...as a structural binding site for GalCer. In mutant patient cells, both cln3 and GalCer remain trapped in the Golgi and never move into the cell's plasma membrane, the Duke team discovered. With GalCer missing from the lipid platforms at the cell surface, apoptosis is inappropriately initiated and proceeds un...Gene expression in liver tumors and patient prognosis
... two distinctive subclasses highly associated with patient survival, according to a new study published in th...umber of genes that accurately predicted length of patient survival and these findings may open the door to the development of more targeted therapies for live...Joslin Diabetes Center adds first affiliate in California at Irvine Medical Center
...reating diabetes and its complications, as well as patient education and research. The venture represents the... Joslin Diabetes Center in Boston, Mass. Diabetes patient Sean Busby, 19, of Mission Viejo, will give a keynote address about his challenge of training for th...NJIT professor receives Presidential Award for breakthrough research with adult stem cells
...rgery proving that adult stem cells taken from one patient can be successfully implanted in another. Researchers originally thought such a transfer might be rejected. And it's not just defective bones that may be regenerated by stem cells and biomaterials. Arinzeh is now testing biomaterials that, in combina...Final Alert: 16th EORTC NCI AACR Symposium
...oratory results underpin epidemiological evidence patient trial now started International trial finds acne-...e can sensitise prostate cancer to radiotherapy patient trials now planned Please note: information above on news briefing & press release topics is for i...Mitochondrial genes cause nuclear mischief
..., as shown by the recent discovery of a hemophilia patient with a NUMT interrupting his clotting factor gene. Much remains to be learned about the functional and temporal dynamics of NUMT insertions, but their potential for harm suggests that many NUMTS, unlike much of the rest of the flotsam that litters ou...Green tea research leads to gum and other products
...damage the salivary gland. "When this happens, the patient can no longer effectively secrete saliva and has a chronically dry mouth," Dr. Hsu said. Dry mouth also affects some people without cancer, including fully 30 percent of the elderly, Dr. Hsu noted. The green tea gum not only protects the tissue but s......nfection. "This is the first time we have seen a patient infected with two different forms of drug-resistant HIV," says MUHC clinician Dr. Jean-Pierre Routy, an associate professor of Medicine at McGill University and co-author of the study. "These emerging drug resistant viruses present a treatment challe...University of Pittsburgh receives $10 million grant for head and neck cancer
.... "Treatment options are limited and often leave a patient with disabling side effects that can have a devast...ncer patients. The grant also includes input from patient advocates who will focus on research-related patient issues and act as a liaison between patients an...Medication reconciliation, pharmacist involvement vital to reducing medication errors, study finds
...ion errors dropped and with them the potential for patient injury. "A medication error, once in a patient's m...rescriber order entry (CPOE) system as part of its patient safety initiative. A previous study at Northwestern Memorial found that a combination of pharmacist...Hopkins scientists use blood proteins to detect ovarian cancer
... analyzed separately to account for differences in patient populations and sample collection techniques. Then, researchers compared protein profile results in these two groups and ultimately narrowed the search for potential marker candidates to the three proteins, one of which (ITIH4) is commonly found at ...Jefferson Lab detector technology aids development of cystic fibrosis therapy
...will initiate an inflammatory response, making the patient even sicker. So that's the last thing we need in the cystic fibrosis patient," Lee says. Lee and his colleagues hope to solve this problem by delivering gene therapy through an aerosol that patients can inhale. In a previous study, he found th...