Enzyme's "Magic" May Hold Key to Anticancer and Antimicrobial Drugs
... conformational changes the enzyme requires to perform its unlinking trick (see figure). A model for the reaction catalyzed by topoisomerase II. Different domains of the enzyme are designated A', B', and C'. The two double-stranded DNA segments involved in th...Race Plus Roaches: A Breathtaking Link
...n, the researchers hope to use this information to perform further studies that better their understanding of the root causes of cockroach allergen. The study was funded by the National Institute of Allergy and Infectious Disease (NIAID). Other researchers include Sampson B. Sarpong, M.D., Robert G. Hamilto...Nutrition Study Reshapes Strategies For Athletes
...ared out of theirsystems, they will be lighter and perform better. Not so, said Houtkooper.During high-intensity exercises, most athletes feel uncomfortable withanything in their stomachs. Blood is diverted away from the digestive systemand to the muscles. But food is fuel, and a series of tiny meals eaten...Honeybees In The Wild Nearly Gone In North America
...ideof both honeybees and their developing young to perform theirblood-sucking duties. The two mites also often carry invadingviruses. Tracheal and varroa mites spread when infested bees comein contact with bees from other hives or when uninfested beesraid the hives of weakened, infested bees, Tew said. "Thes...... capable of using the normal car power supply to perform tasks previously not possible without access to power demands in excess of what was available from a car battery. These microchip based sensors will use special in built heaters and can generate jumps in the sensors temperature of up to 300 degrees c...Surprising Protein Movement Seen In Cells
...ndimmobilized in the organelle, so that they could perform theiressential functions. The new findings, however, show just the opposite. "They are milling all around," said <ahref="http://www.bio.jhu.edu/faculty/Edidin.html">Michael Edidin , a JohnsHopkins University biologist involved in the researc...Cooking And Salad Oils Could Lubricate Cars, Boats, Machines
...such as corn, sunflower and canola, can be made to perform as well or better than the commercial standard for...ped at Penn State, some vegetable oil formulations perform as well or better than the commercial standard, 10W-30 SG, in the usual tests for the abilit...New Software Provides Quick Analysis of ion-Channel Activity
... Buffalo have developed software programs that can perform ion-channel analysis with remarkable efficiency and speed. The researchers have received a four-year, $1 million grant from the National Institutes of Health to enhance the programs and to move them from the current UNIX environment to Windows. Th...Researchers Corral Millions Of Microscopic Membranes
...real. This enabled McConnell and his colleagues to perform key research regarding the nature of the interactions between cells. Groves began working with supported bilayers in 1994. His first discovery was that scoring supported membranes with a pair of tweezers caused them to separate permanently. He took a...Method Eases Making Amino Acids Critical In Medicinal Chemistry
...of one person requires the righthand of another to perform a handshake. Thus, the correct chirality mustbe built into a synthesized biomolecule. "Our chemistry begins with a molecule that is superimposable onits mirror image, and converts it into an aryl amino acid that is nonsuperimposableon its mirror ima...Duke Study Shows Early Marrow Transplant Key To 'Bubble Boy' Disease Cure
...is of SCID is rare because doctors do notroutinely perform a test in newborns to count white blood cells. Such ablood test could pick up children with SCID as well as those with otherserious immune deficiencies that would not be apparent until the childdeveloped an infection. "A simple blood test could allo...Scientists Use Magnetic Field As Alternative To Space-Based Zero Gravity
...ls." "This could even be a way for scientists to perform a range of preliminaryexperiments relative to zero gravity to decide which ones would be moreimportant for including in a space shuttle mission," said James M. Denegre, apost-doctoral researcher in the Department of Molecular Biology, Cell Biologyand...Everyday Technology Underlies First DNA Computer Logic Gates
...a's logic gates rely not on electrical signals to perform logical operations -- as do logic gates in today's... into a series of signals that a computer uses to perform its operations. Today's logic gates process electronic signals from transistors made of materials l...Low Iron Levels Cause Weakness In Women Who Are Not Anemic
...5 percent more efficient in their use of energy to perform the same amount of work. "Only one woman became anemic during the study, but in the rest of the placebo group, we saw a significant reduction in their physical performance compared with the supplemented group," Haas said. "This suggests that iron de...Molecular Piracy Turns Protein Into Traitor
...okine receptor agonist, the virus used genetics to perform a type of biological 'combinatorial chemistry'. This process can be used to produce a family of similar molecules. The virus then tested the related molecules against our own immunological defence mechanisms, making modifications until it found a mol...Further Proof That An Altered Rb-2/p130 Gene Leads To Lung Cancer
...ein remained normal; the protein merely did not perform its job. In contrast, protein levels in lung cancer tissue are much lower than normal. According to Giordano, the first type of test to be developed will accurately describe the stage of cancer--either I, II, III, or IV--of an individua......d older men and womenbetween the ages of 60 and 75 perform worse on working memory tests than matchedgroups of people between 25 and 35. In the study being presented this week, older men tested first withoutsupplementation then again after one month of testosterone supplementationshowed significant ...Husband-And-Wife Team Embarks On Search For Genes Linked To Schizophrenia
...itehead/MIT Center for Genome Research, which will perform a genome-wide scan and collaborate on all data analysis. "Psychosis is a complex syndrome, the most common form of which is schizophrenia," Carlos Pato said. "In at least 20 percent of cases of schizophrenia, other family members are also aff......se carefully crafted building blocks chemists must perform many time consuming multi-step syntheses that also often require very expensive starting materials. "If one could buy imagine purchasing these building blocks from a shop it would have to be Harrods or Bloomingdales" said Dr Hannon. Industry and med...... death,” Dr. Fishel says. “To accurately perform such processes, it is likely that the cell assembles all of the necessary components. Then a switch initiates the actual event. What we’ve found is one of those switches, and that’s the novelty". According to Fishel, this is ...