New Zealand biotech: An emerging global presence
...in clinical trials, with one an hypoxia-activated prodrug for treating solid tumors expected to begin U.S. ...ompany's technology is based on the groundbreaking prodrug research of world-renowned Auckland Cancer Research Centre scientists Drs. Bill Denny and Bill Wilso...Tailor-made cancer drugs: Wave of the future?
...o a strand of PNA than it does to itself. So, the prodrug and the catalytic components each contain a PNA st...synthesis machine and, iIdeally, the catalytic and prodrug components can be synthesized and administered to you within hours." In related work, Taylor said h......onoclonal antibodies, small protein inhibitors and prodrug therapies, all of which may be advanced through structure-based drug design. Background: Corvas serine protease cancer drug programs The modulation of serine protease activity associated with solid tumors is the foundation of Corvas discovery platfor...... First phase II clinical results for amprenavir prodrug (VX-175): VX-175 could provide significant simplification of protease inhibitor-based therapy by potentially allowing dosing of just two or three pills, once or twice a day. Meet with a Vertex medical director or clinical investigator to......he delivery of the compound is accomplished with a prodrug an inert chemical derivative of a drug that can b...the way. Hu's research employs a new and improved prodrug package developed by collaborators in England. This dramatic step in the march toward a cancer cure ...