Brain Protein "Rescues" Neurons From Atrophy
...uch as Parkinson'" disease and amyotrophic lateral sclerosis (ALS). The researchers are postdoctoral fellow David Riddle, Assistant Professor Donald Lo and Associate Professor Lawrence Katz, all of the medical center's department of neurobiology. Their research was supported by the National Institutes of Heal...Second Gene Responsible For Tuberous Sclerosis Complex Identified
..., sleep disturbances, or hyperactivity. "Tuberous sclerosis complex presents us with the full spectrum ofneuro...fact that aroundone-half of children with tuberous sclerosis are moderately to severelyaffected, and this creates lifelong worry for parents and physicians alike...MGH-Led Team Finds Gene For Crippling Neurologic Disorder
...t than Huntington's disease or amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) among the general population and has a higher frequency among Ashkenazi Jews, those of Eastern European ancestry. "We look on dystonia as a 'stealth crippler'," says Xandra O. Breakefield, PhD, of the MGH Molecular Neur......s Alzheimer's,Parkinson's, and amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease). Glen Kisby, Ph.D. and other scientists from OHSU's Center for Researchon Occupational and Environmental Toxicology (CROET) focused on the plant toxincycasin, found in the cycad plant. Cycasin is composed of gl...Scientists Use IGF-I To Grow New Membranes Around Neurons
...rative diseases like diabetic neuropathy, multiple sclerosis and amyotrophic lateral sclerosis (ALS). The devastating symptoms of these diseases are caused by the death or degeneration of periph...Researchers Closing In On Gene For Paralytic Disorder
...sillness, a form of hereditary amyotrophic lateral sclerosis (ALS), to a sectionof chromosome 9. "These results bring us a major step closer to isolating the geneitself," says David Cornblath, M.D., professor of neurology. "When we do thatand clone it, we can find what it does. That should help us t...Gene-Reading Problem Linked To Lou Gehrig's Disease
...ses of thedeadly muscle diseaseamyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. "If these mutations really are specific to ALS and we can develop a test todetect them,that could help us make the diagnosis and begin treatment much earlier in thecourse of thedisease," says Jeffrey Rothstein, M....Jefferson Scientists Link Some Cases Of Scleroderma To Damage From Lingering Fetal Cells
...of scleroderma, an autoimmune disease. Systemic sclerosis strikes about three to eight times more women t... his co-workers examined 69 women with systemic sclerosis who had been pregnant for the presence of the male-specific Y chromosome. A female fetal cell wou...Protein Implicated In Multiple Sclerosis
... the friendly fire that damages nerves in multiple sclerosis (MS). Theyhope that part of this protein eventuall...s lead author. Except for trauma, multiple sclerosis is the most common cause ofneurological disability among young adults, affecting 250,000 to 350,000A...DFG To Set Up 14 New Collaborative Research Centres
...h as cancer, atherosclerosis,psoriasis or multiple sclerosis which are the result of dysregulated or defective signalpathways the new collaborative research centre to be set up at Kiel University will explorethe "Specificity and pathophysiology of signal transduction pathways". Even though the incidence of pan...A Synthetic Peptide Destroys Brain Plaque Implicated in Alzheimer's Disease
...g, including prion disease and amyotrophic lateral sclerosis orLou Gehrig's disease." Amino acids hook together to form peptides and proteins. Amyloid plaque isdeposited in the brain as sheets, explains Dr. Soto. These sheets, which maycontain thousands of protein strings, form a shape called "beta-pleated...Gene Therapy Animal Study Offers Hope For Some Neurodegenerative Diseases
...glaucoma,Huntington's disease, amyotrophic lateral sclerosis (ALS) and Warfan's syndrome,according to the senior author of the study, Matthew M. LaVail, PhD, a professorof anatomy and ophthalmology at UCSF. The finding represents an important breakthrough in the still fledgling field ofgene therapy, which has ......oprevent relapses in the mouse version of multiple sclerosis usinganti-interleukin-12 antibodies for the first time," says Mohamad Rostami, MD,PhD, professor of neurology at Penn's School of Medicine. "Most treatments forMS are first tried out in the experimental allergic encephalomyelitis, or EAE,animal model...Scientists Show For The First Time How Leprosy Bug Targets Peripheral Nerves
...tive diseases such as muscular dystrophy, multiple sclerosis andvarious types of peripheral nerve diseases. "We...diseases, such as muscular dystrophy, and multiple sclerosis andother peripheral nerve diseases. In muscular dystrophies, particularlycongenital muscular dystrop...Jackson Laboratory Researchers Identify Neuromuscular Degeneration Gene
...rological diseases in humans asamyotrophic lateral sclerosis and spinal muscular atrophy. The results are published in a research paper, "Identification of themouse neuromuscular degeneration gene and mapping of a second site suppressorallele," in the December 1998 issue of the scientific journal Neuro...Human Neural Stem Cells Advance Distant Prospect Of Reseeding Damaged Brain
...arctdementia, multifocal diseases such as multiple sclerosis or even global defectswrought by some genetic and dementing diseases, he adds. In this study, the scientists removed cells from deep within theforebrain of one aborted fetus several years ago. When they cloned individualcells, they gave rise ...Autoimmune Diseases Study Shows Differences Between Men And Women
...rthritis, systemiclupus erythematosus and multiple sclerosis are all important autoimmune diseasesthat affect m...n. Twice tothree times as many women get multiple sclerosis and rheumatoid arthritis eachyear, compared to men, and for systemic lupus erythematosus, women outn...Study Of Children's Fillings Finds No Mercury Exposure
...epeople have said mercury fillings caused multiple sclerosis and numerous othermaladies, Dilley said. Comparisons of primary teeth excavated from beneath a 12th-centuryNorwegian church with primary teeth collected from Norwegian children in 1971and 1972 showed the latter contained 10 times as much merc...... to spinal cord injury and disorders like multiple sclerosis andParkinson's disease." In the study, investigators used an adenovirus--similar to a cold virus-- todeliver the beta-endorphin gene to the rat spinal cord. The virus particleswere injected into the spinal fluid, where they were readily taken up by ...Researchers at UNC-CH succeed in synthesizing ginkgo molecule
...in clinical trials for treating dementia, multiple sclerosis andother illnesses. A report on the new work should appear in a chemistry journal in thefall, probably the Journal of the American Chemical Society, he said. Female ginkgo trees, which date back about 250 million years, bearstic...