New Cancer Switch Discovered By Duke Medical Center Pharmacologists
... The peptide is now being distributed by SUGEN for testing on tumors taken from humans, he said. In the October Molecular and Cellular Biology paper, Cortez, Pendergast and graduate student Lisa Kadlec also reported the results of producing slightly altered, or mutated, versions of the BCR-ABL gene. Their ai...Tumor Suppressor Gene Located In Liver Cancer Cells
... in humans when determining whether to pursue the testing of a promising new drug. Jirtle and his colleagues are continuing their studies of the M6P/IGF2r by investigating whether this gene also plays a role in the formation of other types of tumors. After four years of study, Jirtle said, "We are at the e...Second Breast Cancer Gene Located
...e localization of BRCA2 "paves the way for genetic testing forboth BRCA1 and BRCA2." While BRCA1 testing is not yet commerciallyavailable, Winer and other physicians at Duke have been using a test forthat ...DNA Techniques Allow Scientists To Become Pollution Detectives.
...-Just when you thought you'd heard enough aboutDNA testing from the so-called "Trial of the Century," Univers... byisolating E. coli bacteria in water samples and testing it forresistance to antibiotics and by testing its DNA. "E. coli is present in the digestive tracts ...International Research Team Clones New Skin Cancer Gene
... cream that would cure the disease, and to genetic testing for susceptibility to skin cancer. Approximately one million cases of basal cell carcinoma occur each year, and its incidence is on the rise. The new gene, called PTC, is essential for keeping skin cells under control. "Genetic mutation of PTC is t......resistance. Growers were instrumental in both the testing and the naming process. Until they are released, ...ifton Springs, N.Y., has also been instrumental in testing Traminette. He has been selling it as a blend in his "Pearl" and "Gypsy" wines. Marquis, For Eatin...NADC Examines TB In Cattle and Swine
...ee Trade Agreement. The tuberculins used for skin testing in the three countries are preparedby different methods and from different strains of the bacterium Mycobacteriumbovis . The researchers compared tuberculins from each country to determineif there is a need to standardize the tuberculins used in Nor...Water Recycling Project Tested in Turkey Plant
...eceived permission from the agency to beginwork on testing the procedure. "Direct application of ozone in the future is something that's goingto be very big," Baldwin said. "They're using it in Canada andAustralia right now. We're going to be in the process of setting up sometest sites for that." The direc...PET Project Helps Reduce Pollution Threat From Heavy Metals
...ayer works best. Sansalone has spent the last year testing a laboratory versionof the PET system. Experimental results reported at the SeventhInternational Conference on Urban Stormwater Drainage in Germanythis month indicate that the system can virtually eliminatenickel, cadmium, lead and zinc from stormwat......ter inlife as the child starts school. He also is testing to see at what agechildren begin to remember and anticipate actions, as they do when theyplay peek-a-boo....Bog Beetle, Misidentified For 85 Years, Is 'Discovered' At Cornell
...and I made a species identification key and he was testing the key on a variety of specimens," Liebherr said. "Kip found that one of the specimens just didn't fit the key. We suspected we had something new. This species had somehow remained mixed into the Cornell collection along with another extremely com...Bottom-up Ecological Processes Better For Clear Waters, Study Finds
...t data reported in eight papers from 11experiments testing the impact of adding fish versus nutrients to food websand comparing them with controls. Overall, adding small fish, such as minnows,to the top of the small food webs in the studies caused a 75 percent decreasein zooplankton biomass and an 80 percent...ORNL Finds Common Genetic Cause For Epilepsy, Migraine
...Stubbs said. "It could also prove veryvaluable for testing drugs." Now that researchers have identified the likely cause for migraine andepilepsy, the focus turns to how the mutation affects cells' function. "The implicated gene affects the movement of calcium into and out ofspecific brain cells," Stubbs sai...'BirdSource' Website For Citizen-Science Data
...f Science (AAAS) in Seattle. Like a fledgling bird testing its wings, BirdSource is beginning modestly. About 500 "penguins" (online bird-watching guinea pigs) from the 10,000-member citizen-science program FeederWatch began reporting observations from feeders at homes and schools throughout the United Stat...Blood Test Can Identify Some Children With Strep-Related Behavioral Disorders
...rican Journal of Psychiatry. Their study involves testing for thepresence of D8/17 in 27 young people with OCD and tics associated with strep,nine children with Sydenham's chorea, which is a variant of rheumatic fevercharacterized by neurological dysfunction, and 24 healthy children. Theresearchers found th...Duke University Students Devise Devices For The Disabled
...en of brainstorming, parts scrounging, buildingand testing that culminated in a rousing hockey game just before Christmasin the parking lot of Daniel's apartment complex. A video that day captured a smiling Daniel sitting upright in a specialsliding seat that he could push from side to side with his hands a...NIH Team Discovers Endocrine Tumor Gene
... were found, a candidate gene was excluded. After testing and excluding 10 genes the big break came. Out of 15 families, there were 12 different mutations, and the researchers knew this remarkable collaboration had come up with the right gene. "The systematic and powerful process of positional cloning ...Duke researchers find existing drugs can stop fungus that attacks AIDS patients
...th of thefungus in test tube studies. They are now testing the most promising compoundin animals afflicted wi...mmune systemfunction. The Duke researchers are now testing the compound, produced bythe pharmaceutical company Merck, in animals infected with the fungus. ......life," said Rose. He and colleagues are currently testing this possibility in geneticallyengineered tomato plants. This work to date on the LeExp1 gene was supported by the Universityof California. New investigation of the action of the gene will be fundedby a UC Biotechnology-STAR grant ,which seeks to d...