Bacterial Toxin Surprises Scientists
...ane stretches (see images), the protein is able to form an open channel by transporting ju...in--to one side of the membrane, they were able to determine whether the biotin-labeled residue was on the cis ("outside") or trans ...New Cancer Switch Discovered By Duke Medical Center Pharmacologists
...ey fits a lock. "This is the first time we've been able to open a window on what activates normal cABL," said Pendergast. "People have been looking for this molecule, or a molecule with these characteristics, for over a decade." In their experiments, Dai and Pendergast discovered that if they truncate the...Second Breast Cancer Gene Located
... Using DNA from these families, they were able to track the gene to a regionon chromosome 13. A recent finding of a pancreatic cancer with a deletionof genetic material in the precise region of BRCA2 also aided in localizingthe region where the gene resides, Futreal said. The inherited ...Duke Geologists Explore Alternative Way To Measure Ice Age Sea Bottom Temperatures
...our method is quite untested. But if we are really able to do that, that would be monumental."......t less material is required for analysis. "We are able to select pure limestone crystals," said Ku, thus reducing the risk of a sample's being accidentally contaminated by older or younger non-carbonate material. The mass spectrometric method also extends the time horizon for the method, allowing scienti...Duke Researchers Find Second Gene Linked To Blood Vessel Disorder
... disease, it is very important. We would like tobe able to offer some hope to these families." The protein encoded by the ALK1 gene appears to be made almost exclusivelyin the cells that line blood vessels. While researchers aren't sure of itsfunction, it appears to interact with the potent growth facto...New Discovery About Genes Has Implications For Genetic Therapy
... few experiments so far, the researchers have been able to modify some of the information carried by the introns and transfer it to the genes at a very specific site. Much more work will be required before the process could be used for any therapeutic purposes, he said. Lambowitz's team, along with re......rogen (14N and 15N) isotopes, the researchers were able totrace energy flow through the food web from the microbe producersthrough the intermediate grazers to the carnivores at the top ofthe food web. "All the data show quite clearly that these animals are basedon chemoautotrophic carbon production. They ...DNA Techniques Allow Scientists To Become Pollution Detectives.
...F'sInstitute of Food and Agricultural Sciences are able toaccurately point the finger at who is polluting ... other harmfulbacteria in the water. We hope to be able to have folks send uswater samples and to run these tests on it for them. We thinkthis type of test ...Cornell Researchers Precisely Date Wood From Ancient Tomb In Turkey
...long with radiocarbon dating, the researchers were able to determine the exact year that some of those logs were chopped down. They report that logs used to build the inner chamber of the Midas Mound Tumulus, a massive tomb named for King Midas of the Phrygians and located at the Gordion archaeological s...Nutrition Study Reshapes Strategies For Athletes
...ryenvirons of Atlanta during July. "They have been able to realize through the training program that by doingfluid replacement, they will actually do better in their performance," saidHoutkooper. "It's not intuitive for them to keep drinking. Athletes candrink enough fluids to satisfy their thirst, but wi......hardiness derived from American species. They are able to stand up to short Northeastern growing seasons and exhibit some disease resistance. Growers were instrumental in both the testing and the naming process. Until they are released, grapes are referred to by number only. A name can make or break a...Researchers Use Hydrated Lime To Reduce Toxic Selenium Emissions
...s most effectiveat 400 to 600 degrees Celsius, and able to "capture"up to five percent of its weight in selenium. At higher temperatures,calcium selenite is thermally unstable, which reduces the efficiencyof selenium capture. The scientists compensated for this by injecting the dry sorbentfurther away fro...Photosystem I -- An Intermediate Step -- May Not Be Necessary For Plants
... explained they found that mutant algal cells were able to grow and survive in near-normal conditions. "N...x before and after the experiments. Owens was not able to detect the key PSI protein. Does this mean that PSI is not necessary for normal photosynthesis?......will develop new sensor technologies which will be able to provide the detailed analysis required for constant monitoring of both car emissions and air quality in the driver's cabin. Dr Julian Gardner in the University of Warwick's Department of Engineering will co-ordinate the Europe wide research cons...Researchers Find Possible New Route to Making Cancer Cells Vulnerable
...epump. When FKBP12 is missing, the pump may not be able to open and closeproperly to expel the drugs from the cell." The researchers say the findings could change the way doctors evaluatepotential MDR-blocking drugs. Such drugs would be similar in shape to FK506and rapamycin, but without suppress...Surprising Protein Movement Seen In Cells
...chc.edu/htterasaki/flip.html The researchers were able to study the movement of proteinsthrough a revolutionary technique that uses light-emitting, orfluorescent, molecules taken from a jellyfish, Aequorea victoria.DNA from the jellyfish's fluorescent protein is fused with theDNA of proteins biologists w...Virginia Tech Researchers Receive Patent For Rapid Virus Detection Technology
...r of human fecal contamination of water. Ifviruses able to infect E. coli are present in a water sample,then its host, E. coli must also be present. "An advantage of the rapid virustest is that viruses are usually live longer in water samplesthan bacterial cells, thus presence of virus can indicate ......r forBiotechnology -- have devised amethod that is able to overcomeformidable obstacles. In very simple li...evertheless,to find the analogous genes, wemust be able to recognize these differentlyspelled words written ondifferent pages as the same message." Even the...Ocean Sediments Contain Record of Past Vegetation Fires in Africa
...ay be wrong." Current models have not been able to determine exactly how the total amount of carbon on earth is distributed. According to Verardo, "This new data sheds much-needed light on where the 'missing' carbon may lie: in ocean-bottom sediments laden with charcoal from fires on land."...