Tag: "abnormal" at biology news
Scientists identify molecular step that causes intoxication
...ed to alcohol. As they predicted, worms with these abnormal
BK channels acted just as intoxicated - without any exposure to alcohol - as normal worms did under the influence, confirming the new finding. The research began with a search for genes that account for alcohol's intoxicating effect. The scientis...
Drug shows promise for Ebola virus treatment in primates
... the virus itself. Ebola causes coagulopathy, or abnormal
blood clotting, which ultimately leads to massive ...ody, forming localized clots that pave the way for abnormal
bleeding. Using rNAPC2, according to Geisbert, essentially blocks the harmful effects of tissue fact...
Early treatment can prevent severe vision loss in premature infants
...o identify premature babies at the highest risk of abnormal
blood vessel growth in the retina and subsequent b...r portions of the retina, slowing or reversing the abnormal
growth of blood vessels A potential side effect of these treatments, known as retinal ablation, can ...
Hope available for patients with anemia and myelodysplastic syndrome
...Myelodysplastic syndrome (MDS) is characterized by abnormal
blood-forming cells of the bone marrow, which prod...ells effectively, and many of the formed cells are abnormal
or defective. The abnormal
cells are usually destroyed before they leave the bone marrow or shortly...
Aspirin use safe and effective in patients with abnormal red cell counts (or with polycythemia)
... thrombosis in patients with polycythemia vera, an abnormal
increase in blood cells resulting from excess prod...to the disease after being diagnosed. However, the abnormal
bone marrow cells may begin to grow uncontrollably in some patients leading to blood hyperviscosity....
Novel therapies show promise against myeloid leukemia
...of leukemia. Imatinib (Gleevec), which blocks the abnormal
protein driving the overproduction of abnormal
white blood cells, has become the standard therapy for patients not undergoing stem cell transplanta...
Yeast model yields insights into Parkinson's disease
...e gene's actions under normal conditions and under abnormal
conditions to learn how and when the gene's product, alpha-synuclein, becomes harmful to surrounding cells. The scientists created a yeast model that expresses the alpha-synuclein gene, which has been implicated in Parkinson's disease (PD). Yeast m...
Yeast helps researchers better understand Parkinson's mystery
...caused by proteins like aSyn that can misfold into abnormal
shapes and lose their ability to function correctly or even wreak havoc in the cell. The Lindquist lab has been studying human proteins in yeast for several years, learning more and more about how proteins misfold and what happens when they do. The ...
Childhood sleep-disordered breathing severity related to tonsil size, oropharyngeal volume
...eep-disordered breathing (SDB) is characterized by abnormal
breathing patterns during slumber, with sleep apnea the most recognizable form. Although SBD is commonly known to affect adults, few realize that about two percent of children are affected. The mechanisms of SDB during development are unclear. To ...
Doppler ultrasound predicts risk of miscarriage
...rook, Ill. "Over 99 percent of pregnancies with an abnormal
Doppler pattern do not continue." The Doppler test measures the speed of red blood cells moving through vessels to determine pressure dynamics within the embryo's heart. Miscarriage is the most common complication of human gestation, occurring in...
Chromosomes are 'nibbled' before they fuse, researchers report
...ht be able to find targets in that process to push abnormal
cells toward death and away from trying to repair themselves," says Carol Greider, Ph.D., professor and director of molecular biology and genetics at the Johns Hopkins School of Medicine. "Now it turns out that what we've always thought was the first...
Nanotech instruments allow first direct observations of RNA 'proofreading'
... corrects them before they have a chance to create abnormal
proteins. The error-prone nature of RNAP is not surprising given the size of its task. In human cells, for example, the RNAP enzyme has to make precise genetic copies from a DNA double helix that consists of billions of chemical bases known as A, T, ...
Tip sheet for the November 25, 2003 Neurology journal
...t McArdle's disease, an inherited disease in which abnormal
amounts of glycogen accumulate in skeletal muscle resulting in weakness and cramping. An accompanying editorial "Echo of silence: Silent mutations, RNA splicing and neuromuscular diseases" makes the science of this paper understandable. Levodopa add...
Calcium channel involved in coronary artery relaxation
...n constricted coronary arteries that resembled the abnormal
coronary arteries seen in the mice that lacked the channel. Abnormal or restricted blood flow to heart muscle can lead to heart damage because cells that are deprived of oxygen and nutrients die. In the heart, the dead muscle cells cannot usually be ...
Investigational cancer drug prevents abnormal brain growth, reverses seizures in lab mice
...xperimental anti-cancer drug to prevent or reverse abnormal
brain cell growth that is caused by lack of the an...arts of the brain in young mice, but also reversed abnormal
growth in certain areas of the adult mouse brain. In addition, CCI-779 reduced the frequency of seiz...
High heart risk for lupus patients linked to death of cells lining blood vessels
...s, and 43 healthy controls. The lupus patients had abnormal
vascular function that was impaired to the same ex... patients and coronary artery disease patients had abnormal
flow-mediated dilation, while normal control subjects did not. In most patients tested for vascular ...
Aspirin may not be strong enough to prevent clots in some heart patients
...otting agents to aspirin therapy, and the study of abnormal
genes that might affect platelet function....
New technique helps shed light on progression of dementia
... may slow down as a result of mini-strokes and the abnormal
regulation of blood vessels, which contributes to ...w gives us better insight into the consequences of abnormal
Major new finding on genetics of Parkinson's disease zeroes in on activity of alpha synuclein
...e October 31, 2003, issue of Science , shows that abnormal
multiplication of the -synuclein gene can cause th...ests another way of looking at the consequences of abnormal
protein deposition in a variety of neurological diseases, such as Alzheimer's disease. The Science...
New therapies under development promise improved relief for Non-Hodgkins Lymphoma cancer patients
...20 antigen that may be found on normal, as well as abnormal
B cells. In addition, other antigens such as CD4, CD22, and CD30 are being targeted. Some biotech firms are also trying gene therapy and vaccines to treat patients. These treatment methods could be advantageous as they avoid some of the side effects ...
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