Adaptive changes in the genome may provide insight into the genetics of complex disease
... in theregion, TRPV5, are also involved in calcium absorption in the kidney,intestine and placenta. Scientists had previously found that geneticvariation in a gene promoting lactose-tolerance in milk drinking Europeanpopulations was selected for some 10,000 to 20,000 years ago. The latestdiscovery seems to comp...JCI table of contents, 16 August, 2004
...tokinin-1 receptor promotes intestinal cholesterol absorption and susceptibility to cholesterol cholelithiasis AUTHOR CONTACT: Martin C. Carey Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA Phone: (617) 732-5822; Fax: (617) 730-5807; E-mail: mccarey@rics.bwh.harvard.edu View the PD...Infant rats eagerly accept high concentrations of alcohol upon first exposure
...ely due to active drinking, not just inhalation or absorption through the skin. "Establishing unusually high alcohol ingestion at this age is important for understanding the relationships between brain and alcohol intake," he said, "because we know how the infant brain differs from that of older rats, so we c...Study links high carbohydrate diet to increased breast cancer risk
...st cancer, possibly because fiber may modulate the absorption of carbohydrates and thus affect the glycemic response. "This study raises important questions about high carbohydrate diets, particularly among populations or individuals prone to insulin resistance. However, one study is not enough to make major c...From science fiction to reality: Nanomedicine brings fresh hope to the medical world
...ls and nanotubes through inhalation, ingestion, or absorption through the skin are increasing. Although there is sporadic evidence supporting these possible hazards, it is essential for the nanomedicine community to take the lead in defining the risks associated with nanotechnology. Proactively supporting exper...DFG presents the 2004 MAK and BAT value lists
...ly labelled with the warning "H", which means that absorption through the skin together with inhalation may significantly contribute to their toxicity at the workplace. This warning label was checked and confirmed for two more working substances, bronopol and p-toluidine. The section BAT values, biological guid...FDA approves VYTORIN, first and only to powerfully reduce LDL cholesterol through dual inhibition
...ction of cholesterol in the liver and blocking the absorption of cholesterol in the intestine, including cholest...hibition of cholesterol production by the body and absorption in the small intestine Cholesterol in the blood is derived from two sources production by the bo...Rutgers cancer prevention expert calls for FDA action to reduce colon cancer and osteoporosis
...ead to cancer, Newmark says. Vitamin D aids in the absorption of dietary calcium by the body. For decades, researchers have recognized the role of calcium in reducing the risk of diseases such as osteoporosis and colon cancer, but this has not been reflected in federal regulations. Newmark and his co...Healthy fats and oils essential to satisfy calorie-conscious consumers
... are integral to a balanced diet and assist in the absorption of fat-soluble vitamins. This is driving the R&D efforts toward reduced fat and lower calorie foods without altering traditional eating habits. "Fat-based replacers are gradually gaining momentum in the market since they produce fats that eliminate e...Research shows oceans are becoming more acidic
...being are being added to the oceans each day. The absorption of carbon dioxide by the oceans is considered a beneficial process that reduces the concentration of CO 2 in the atmosphere and mitigates its impact on global temperatures. However there is growing concern over the price of this service. For the sym...Acamprosate: potential medication for treating alcoholism
...gest that acamprosate does not alter the rate of absorption or elimination of alcohol by the body, the disrupting effects of alcohol on performance tasks, or most of alcohol's mood effects, she said. "The glutamate system is one of the most strongly affected by chronic alcohol use," added Raymond Anton, D...Funding to commercialize technologies of UC San Diego engineers tops $1.2 million
...oped a novel technique to enhance the near-surface absorption of photons by semiconductors using engineered nanostructures placed on the surface of the semiconductor. The approach leads to a substantial increase in optical absorption, even in silicon-based semiconductors. Now, Yu plans to adapt this technology ...Functional genomics enables easy target identification and drives drug discovery
...alify for Phase I clinical development. Human drug absorption is another approach to obtain accurate PK and ADME...ld provide a detailed understanding of the complex absorption process at distinct intestinal sites," says Sankaran. "This may be critical for quicker decision-mak...Scientists report how protons induce water cages
...added), and then monitored changes in the infrared absorption that occurred upon addition of each new water molecule. "The idea was brought to my attention by John Fenn, Yale Professor Emeritus of Chemical Engineering and Nobel Prize winner in Chemistry '02," said Mark Johnson, professor of chemist...Vanderbilt doctors find citrus soda interacts with cyclosporine, maybe statins
...itrus products, on the disruption of excretion and absorption of cyclosporine and certain other prescription dru...st beverages containing bergamottin also alter the absorption and excretion of statins (HMG-CoA reductase inhibitors), which would affect a high percentage of the...Water molecules clump more loosely than previously thought
...ch was the first to apply a technique called X-ray absorption spectroscopy to the local structure of water. The technique, developed by SSRL, among other laboratories, bombards a material with X-rays that are finely tuned to excite particular electrons in a molecule's structure. Careful measurement of the scatt......ch was the first to apply a technique called X-ray absorption spectroscopy to the local structure of water. The technique, developed by SSRL among other laboratories, bombards a material with X-rays that are finely tuned to excite particular electrons in a molecule's structure. Careful measurement of the scatte...Design of composite materials that detect terahertz discovered
...ror agents, like anthrax happen to have a distinct absorption in the terahertz range, and since terahertz can penetrate clothing, it is also of interest for airport screening of weapons and explosives. Terahertz rays could also help pilots guide airplanes in foggy weather because water doesn't scatter terahertz...Transporter's function provides support for eating vegetables, limiting antibiotics
...pically expressed in the colon since digestion and absorption take place almost exclusively in the small intestine. But the finding made him think of what he has long taught medical students about colon cells and how they need short-chain fatty acids to stay healthy. "We go and test it with our clone sitting in...