Tag: "act" at biology news

Molecular motor implicated in tissue remodeling

...ed for an energy source. While most molecules that act as motors are inside cells and get their energy from a ubiquitous high-energy molecule called ATP, the team found that MMP-1 gets its energy by breaking the molecular bonds in the collagen filament it is attached to. "In fact," Goldberg says, "with ...

UT Southwestern biochemist honored with NIH Director's Pioneer Award

...Francisco dedicated to the discovery of drugs that act through the regulation of gene expression. ...

Wisconsin scientists develop quick botox test

... technology could be the development of drugs that act like a prophylactic to confer protection from botulinum poisoning. The new tests, according to Chapman, can be conducted with ordinary lab equipment. It works by introducing into cells bioluminescent proteins whose glow is extinguished in the presen...

Master of antimalarial resistance

... gene is located in this digestive vacuole and may act as its gatekeeper. In chloroquine-resistant malaria, mutations in pfcrt may encourage chloroquine to "leak" out of the vacuole before it has a chance to stop the heme detoxification process. The pfcrt mutations seen in halofantrine and amantadine res...

Pollutant causes delayed flowering in plants

...n light, while others are autonomous pathways that act independently of external cues. "However, nobody knew that nitric oxide was involved in these pathways. And nobody knew that plants would be affected by external concentrations of nitric oxide, as might be caused by air pollution." Such biochemical ...

Brown research reveals key insight into memory-making

...-receiving neuron, known as the postsynaptic cell, act like gates, opening in response to chemical messages from a neighboring neuron. During LTP, extra AMPA receptors appear, increasing synaptic strength. But where do these extra receptors come from? Michael Ehlers, associate professor of neurobiology a...

Experimental drug shown to block mutant protein causing blood disease

...xplains Stone. Tyrosine kinases are molecules that act as biological switches inside cells, regulating processes including cell division and growth. Abnormal kinases have been discovered to be major culprits in many forms of cancer. Because inhibitor drugs strike the abnormal kinases in cancer cells with...

Binocular rivalry: Fulfilling visual expectations

...about what we expect to see and that these signals act to constrain our interpretation of incoming visual information. The separation between our eyes gives us two slightly different views of the world. Ordinarily, our brain will fuse these two views to add depth to our visual world. However, if the t...

'Fossil genes' reveal how life sheds form and function

...he discovery of a set of seven genes caught in the act of fossilization. In the Japanese yeast, known to scientists as Saccharomyces kudriavzevii, the Wisconsin scientists found the decaying genes that, when intact, are all functionally related and make up a pathway that permits the organism to convert ...

Information system to help scientists analyze mechanisms of social behavior

...brain of individuals that are captured in the very act of performing their normal activities." While the experimental model is an insect, the researchers will use broad categories of social roles that could potentially apply to higher organisms, including humans. To further support comparisons across or...

JCI table of contents September 15, 2004

...-like non-steroidal anti-inflammatory drugs, which act to inhibit the action of COX. Two prostenoids called PG I2/prostacyclin (PGI2) and thromboxane A2 (TXA2), are ele-vated in individuals with atheroscle-rosis, but their roles in the initiation and development of atherosclerosis remain ill-defined. To...

Picking prostanoids to provide protection

...-like non-steroidal anti-inflammatory drugs, which act to inhibit the action of COX. Two prostenoids called PG I2/prostacyclin (PGI2) and thromboxane A2 (TXA2), are ele-vated in individuals with atheroscle-rosis, but their roles in the initiation and development of atherosclerosis remain ill-defined. To...

First glimpse of DNA binding to viral enzyme

... as targets for drugs to block the interaction and act as antiviral agents, Mangel said. The scientists have already begun looking for such drugs and hope to have the National Institutes of Health test some of them for anti-viral activity within a year. ...

AACR applauds NCI initiative on nanotechnology

...urning to smaller and smaller probes that not only act as microscopic sentinels, but also as tools capable of interfering with these processes. For this reason, the American Association for Cancer Research applauds the new initiative announced today by the National Cancer Institute to harness the power o...

Laboratory grows world record length carbon nanotube

... in one segment while the rest of the nanotube can act as a conductor to transmit the signal. Other uses include applications in nanoscale electronics, where the nanotubes can be used as conducting or insulating materials. For example, joining together two nanoscale carbon tubes with differing electroni...

A probable cause for high blood pressure identified - shows links with diabetes

...o treat hypertension, such as clonidine, appear to act by displacing imidazole-4-acetic acid-ribotide fro...ate these drugs have been problematic because they act at multiple receptors and thus have many side effects. Now that we know the endogenous molecule that...

There and back again

...mesenchymal-epithelial transition. Rac1 appears to act in a tightly constrained dose-dependent fashion to regulate MET, as both constitutively active and dominant negative forms of the protein disturb somitic epithelialization. Takahashi and colleagues further demonstrated that developing somites in the ...

K-State's National Agricultural Biosecurity Center receives $1.3 Million from Department of Defense

...ponders with knowledge, skills and capabilities to act effectively in the face of an agroterrorism incident," Vanier said....

Endangered species list more bleak than originally thought

...n trying to determine how many other species could act as hosts and factoring that degree of dependence into the study." The researchers believe these processes have been largely overlooked in the past because some of the most susceptible organisms are uncharismatic parasites, but other more popular anim...

NJIT professor receives Presidential Award for breakthrough research with adult stem cells

...are biomaterials, such as calcium phosphates, that act as a framework for stem cells, allowing the cells to repair bone as the biomaterial degrades. Arinzeh performed animal studies on rats with bone defects; she also did cell-culture studies. Both showed that the biomaterials stimulated stem cells, prod...

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