Tag: "act" at biology news

Researchers describe long-perplexing 'magic spot' on bacteria

...roteins from different bacteria look similar, they act similar, too," she said. Without RfaH, enterobacteria can't cause disease, Artsimovitch said. It's plausible that drug developers could design an antibiotic that knocks out RfaH, effectively shutting down a bacterium's virulence. "We're trying to giv...

Cellular problems found behind complex obesity syndrome

...stics overlap with those of BBS." Microtubules act as the roads that chromosomes travel in order to move to opposite sides of the cell during cell division. They also transport molecules and packets of molecules to the cell membrane for release from the cell, and are the primary skeleton in cellular ...

Researchers discover cold virus can 'hit and hide'

... cold virus causing bronchiolitis in children, can act as a 'hit and hide' virus. It was thought that the...shaw says: "Some people may be 'carriers', able to act as a source of new outbreaks in children. If RSV is a 'hit and hide' virus, this could explain where...

Hopkins scientists overcome main obstacle to making tons of short, drug-like proteins

...sually less than 40 building blocks long, peptides act as important messengers and hormones in the body. But because their building blocks, called amino acids, are quickly recycled, peptides made from the 20 naturally occurring amino acids don't last long enough to be useful as medicines. However, adding...

DELTA mission and ESA astronaut dock with ISS

...h the Expedition 8 crew for the last six months to act as an emergency lifeboat. Kuipers will be the Flight Engineer on the return flight in Soyuz TMA-3, which flew ESA astronaut Pedro Duque to the ISS on the Cervantes mission in October 2003. Soyuz TMA-4 will remain docked with the ISS for approximately...

Stretching DNA on a tiny scale, researchers probe the basis for its compaction

...ask single-handedly, or whether multiple complexes act cooperatively, but the new findings and techniques employed here establish a solid foundation for further work on such questions....

National Academies news: 72 new members chosen by academy

...re. It was established in 1863 by a congressional act of incorporation, signed by Abraham Lincoln, which calls on the Academy to act as an official adviser to the federal government, upon request, in any matter of science or technolo...

UGA professor Jeffrey Bennetzen named to National Academy of Sciences

...service to the nation as its dominant purpose. The act also named 50 charter members. Subsequent executive orders have affirmed the importance of the National Research Council and further broadened its charter. The National Academy of Sciences established the National Academy of Engineering in 1964 and t...

Study is another step in determining if curry can protect against Alzheimer's

...les generated through mitochondrial metabolism can act as causative factor of abnormal function and cell death. Various toxins in the environment can injure mitochondrial enzymes, leading to increased generation of free radicals and oxidative stress, that over the life-span would eventually play a major ...

How do animals exposed to 24-hour light retain their wake-sleep habits?

...rer the horizon at one part of the day, this might act as a clue for the biological clocks. As the American economy requires its work force to abandon traditional work hours of "nine to five," it becomes more important for us to understand how the body's biological clock can respond to unnatural light cl...

New approach offers potential drug-discovery shortcut

...'s website. "Currently most drugs are designed to act on a specific protein, but for most diseases we still don't know what the protein targets should be," says Randall Peterson, PhD, of the MGH CVRC, the paper's lead author. "This is a totally different approach that shows how, without knowing the bes...

Exercise reduces blood estrogens, risk for breast cancer in post menopausal women

...rum," Dr. McTiernan said. Increased levels of SHBG act to regulate the circulating levels of free, biologically available estrogens. Dr. McTiernan noted studies showing that women on low-fat diets reduced serum levels of estradiol by 6.2 percent. The active women in the exercise study reduced estradiol ...

A new hypothesis about autoimmunity. Is it possible to be too clean?

...full of immune cells. Increased numbers of T cells act as a buffer against the emergence of self-reactive T cells by shutting down homeostatic expansion. This hypothesis could explain a discrepancy in the number of cases of autoimmune disease in developed and developing countries. Disease rates have been...

Newborn lambs' central heating system could aid fat busting in humans

...r to lambs: brown fat is present in the newborn to act as an internal central heating system maintaining body temperature and preventing hypothermia, but rapidly disappears as brown fat is irreversibly replaced by normal white fat. Now, researchers based at Imperial's Wye campus in Kent are determining t...

U of T researchers isolate gene for Crohn's disease

...lved in this disease, we can learn how these genes act together to cause disease. This information will help us identify potentially preventable environmental triggers as well." Other U of T researchers were Bill Newman, David Cescon and Gordon Greenberg, (also at Mount Sinai Hospital), Laurence Rubin (a...

Researchers make major gain in understanding how prions jump species

...orm. "While abnormally shaped proteins can readily act as templates to convert normal prion proteins from the same species, cross-species seeding is believed to be highly restricted due to differences in the sequence of amino acids, the basic building blocks of each protein," said W. Surewicz. However, ...

Ancient Greeks help scientists build environmentally friendly nano devices

...refully crafted nano-sized holes in the films also act as pockets for other useful Nano-particles, tethering them in place ("Contained Nano"). The nano-honeycomb structures can provide the equivalent of a scaffolding to assemble nano-devices or sensitive nano-sensors on ultra-small scales. The ultra-high...

Genetic trick adapted from viruses makes gene therapy vectors more versatile

...ng in certain cells or make multiple proteins that act together as potent drugs against cancer and other diseases. The technique is based on a genetic trick, called a self-cleaving 2A peptide, which is used by some viruses to produce multiple proteins from a single length of DNA; i.e., a single, long pro...

Leptin rewires the brain's feeding circuits

...edman. "And I'm sure it's the case that leptin can act in many different ways. But what we have discovered is a particularly striking modality of action that wasn't what we initially would have suspected was the likeliest." The major problem in studying in detail the action of leptin on NPY and POMC neur...

How DNA copying enzyme 'stops the presses' for repair synthesizing enzyme

...e to instantaneously capture the polymerase in the act of processing a mismatch. The researchers plan to use flashes of ultraviolet light to unleash "caged" chemicals that trigger replication -- and at the same time use flashes of X-rays to illuminate the crystal. This approach may allow the researchers ...

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