'Defensive' action by influenza viruses demonstrated by Hebrew university researcher
...ally seal the channel. Arkin notes that the latter action is the more surprising and unexpected one. While c...viously only concentrated on examining the binding action of the blocker to the viruses, but not the process taking place in the viruses'channel. Thus, there ...Single isolated mouse skin cell can generate into variety of epidermal tissues
...t it hasn't been clear whether this was due to the action of one stem cell or a bag of different cells," Fuchs says. In the current scientific paper, the Fuchs team reports on a new system to isolate these cells that avoids the need for genetic manipulations of the mice, and hence may make it applicable in ...Small, Smac-like molecule encourages death of cancer cells
...as have developed a small molecule that mimics the action of a key "death-promoting" protein in cells, a finding that could lead to more effective cancer therapies with fewer side effects. In the Sept. 3 issue of the journal Science, the researchers report on this new compound and how it behaves like the ce...Diabodies act as guided missiles targeted to mammary tumor growth
...or cells used in the studies lacked the protective action of that apoptosis-inducing gene. The mammary tumor cells also internalized the HER2-bound diabody fifteen times more rapidly than did the ovarian tumor cells. Ongoing studies by Adams and his colleagues are aimed at determining refinements in the ...Protein involved in childhood disorder linked to cancer
...se protective processes is coordinated through the action of signaling systems that detect DNA damage, interpret and amplify the signal, and call in appropriate repair and checkpoint responses," said Stern and Xu. "Impairment of checkpoint signaling systems can lead to excessive accumulation of mutations or...Scientists fear new Ebola outbreak may explain sudden gorilla disappearance
...o the north. Scientists say multiple courses of action should be taken immediately: Field researchers already in the region, from groups including Ecofac, Wildlife Conservation Society and the University of Rennes, need greater human and financial resources to enhance monitoring in the park, in order ...The future of HIV therapeutics is brightening, according to Gladstone Institutes Director
...ombined effects effectively overcome the antiviral action of APOBEC3G. The fact that Vif must bind to APOBEC...ment. The goal is to block the assembly or ensuing action of Vif on APOBEC3G, thereby preserving intracellular expression of APOBEC3G. GIVI scientists are now...The insect police: Why social insects punish cheating comrades
...e investing in only the queen's reproduction. Such action can be severely penalized by other workers - in honeybees, where this behavior was first shown, workers remove worker-laid eggs within hours by eating them, and, in some ants, more draconian methods lead to the mutilation of the culprit caught in the...Genetically-engineered 'marathon mouse' keeps on running
...l animals. And, they will explore the mechanism of action of the protein on the multitude of genes involved in the physiological changes they observed....Penn scientists identify novel pathway in aneurysms
...ay," says Funk. Drugs that block the formation and action of this pathway are currently used to treat inflammation in the airways of asthmatics. "Perhaps they may become useful to treat patients who are susceptible to developing aortic aneurysms by blocking their progression and eventual rupture," he adds. ...Newly discovered protein may be key to muscular dystrophy
A defect in the action of a newly discovered protein may play a central role in muscular dystrophy, a disease of progressive muscle degeneration with no known cure. Scientists at UCSF's Ernest Gallo Clinic and Research Center discovered in an animal model of the disea...MIT research that stops pain of needle jabs gets FDA approval
...e method is simple and painless, and speeds up the action of lidocaine--a topical anesthetic commonly used in pediatrics and on critically ill adults and children who must endure repeated needle sticks--it could become standard procedure in doctor's offices and hospitals. Another use would be before painful...Enzyme activation appears key in helping internal clock tell night from day
...search, the scientists blocked the phosphorylation action of PKG-II during the normal cycling of the clock. By doing so, they disrupted the key activity of this kinase enzyme that adds phosphates to proteins, a signaling mechanism necessary for information transfer in cells. The internal clock produces the...New mechanism for display of foreign proteins to immune system
...ells called cytotoxic T lymphocytes to spring into action and battle the abnormal cells. One of the ways that sentinel cells accomplish crosspresentation has been described in detail. Antigens are internalized into a specific compartment, transferred to the cytosol, chopped up by proteosomes, and then trans...Stanford researcher's findings may shed light on common, deadly birth defect
...ion of the brain and face. Blocking this protein's action at varying developmental stages yields very different anatomical results - including one in which only the exterior, or the face, is affected while the scaffolding, or the brain, is left unscathed. The results not only shed light on a common cause of...Technology already exists to stabilize global warming
... to keep up with increasing demand. Case for action Pacala and Socolow said that limiting ca... how accurate we were." A strong case for action comes from three lines of evidence, said Pacala. First, investigations of the Earth's climate over t...Alterations in vitamin D receptor gene increase prostate, breast cancer risk
...the receptor for vitamin D reverse the anti-cancer action of the sunshine vitamin, increasing the risk of breast cancer in Caucasian women and prostate cancer in African-American men, according to two new studies. The results, in journals published by the American Association for Cancer Research, underscore...Common call for action on European Research Council (ERC)
...ropean scientific organisations calling for urgent action on the establishment of a European Research Council (ERC) a pan-European funding organisation for basic research at a European level. A mass petition of this kind on science policy is almost unheard of in Europe and indicates the importance these or...JCI table of contents, 2 August, 2004
...s involved in appetite. Leptin works through the action of several small proteins called neuropeptides, su...ase Has New Antitumor Tricks TITLE: Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects AUTHOR CONTACT: L......e noted that marine reserves are an example of one action that is already improving an ecosystem. "Ecologists have been known for 'gloom and doom,' but now we are making recommendations for things that can be done," he said....