Study shows benefits to newborns from federal ban on insecticides
...g the Environmental Protection Agency's regulatory action implies important benefits for the children's future health and development. At the same time, the results highlight the need to address continuing prenatal exposures to these and other toxic pesticides." The study is part of a broader, multi-year...Activity of calcium-handling gene appears to prevent cardiac arrhythmias
...ure patients, a concern was raised that the gene's action of increasing calcium transport in heart cells could stimulate arrhythmias. In addition, recent research elsewhere has implicated calcium in the generation of ventricular fibrillation and the rapid rhythm called ventricular tachycardia. The current ...Failure of DNA repair mechanism precedes final stage of deadly leukemia, new Penn study shows
...y blood cancer, is preceded by the unique blocking action of a blood cell's normal cycle of DNA production and repair. The researchers linked the blocking action to a known oncogene, BCR/ABL, and suspect it to be the cause of blast crisis, the second and final s...More evidence of major global extinctions
... It is on their efforts that so much conservation action continues to rest." "Sadly, many of the birdwatchers who contributed to the first Breeding Atlas, which covered the period 1968 to 1972, are no longer with us. It is wonderful that their records can still be used to show that birds are good indicat...Natural enemies help scientists untangle tropical forest food webs
...ecology through shared parasites, and confirms the action of an important ecological theory in the highly biodiverse rain forest environment. Ecologists have long believed that species which have nothing in common but a 'natural enemy' - something that eats or parasitises both of them - may interact indirec...Combination therapy drives cancer into remission
...tibiotic rapamycin. Rapamycin treatment blocks the action of an Akt "effector" protein called mTOR and thereby restores the programmed cell death mechanism in Akt-positive lymphomas. The drug chosen to trigger the programmed cell death mechanism was a different antibiotic called doxorubicin. Like many tradi...JCI table of contents, 15 March 2004
...eceptors, CCR2. The use of agents that block CCR2 action in RA mouse models partially reduces relevant RA symptoms, indicating this receptor may play a role in advancement of the disease. Completely unexpected results, however, resulted in two different mouse models for RA that had the CCR2 gene deleted: ...Astrazeneca announces EU marketing approval for Faslodex(TM)
...gen receptor in breast cancer cells. This mode of action is different to the aromatase inhibitors that work...unwanted side effects. 'Faslodex's' unique mode of action creates a new type of endocrine treatment for oestrogen receptor positive breast cancer the first t...Protease-inhibitor cocktail protects, increases anti-microbial action of promising new peptide
...that the PIC protects and increases anti-microbial action of this peptide," said Wei. "Our next step is to see if the peptide-protease inhibitor combination performs equally well in an animal model."...Scientists call for less destructive remediation at DOE sites
...strictive cleanup criteria" would be Congressional action that ensures continuing Federal control of some contaminated DOE sites, and thereby eliminate the hypothetical "site resident" scenario. The authors maintain that continued Federal control would minimize public health risks, environmental damage and...Rimonbant shows promise in addressing multiple risk factors
...with exaggerated food intake and/or smoking. This action results in weight loss, improvement of cardiovascular/ metabolic risk factors in overweight/obese patients and reduces tobacco dependence without post cessation weight gain in people who smoke. ABOUT RIO TRIALS (RIMONABANT IN OBESITY) RIO-Lipids is...Biochemistry and Molecular Biology: Research at the Interface of Biochemistry and Human Health
...ies such as the molecular basis of the therapeutic action of aspirin, the mechanisms that modulate T-cell response, and the targeting of membrane-spanning receptors by new therapeutic drugs; and an intertwined series of symposia along 10 themes, which cover the major areas of cellular biochemistry. The mee...UN study shows environmental consequences from ongoing boom in personal computer sales
... is a need for epidemiological studies, yet little action taken to see that these are done. A group of chemicals called brominated flame retardants used in circuit boards and plastic computer cases is of particular concern. Recent studies in the United States, Canada and Sweden show that concentrations of t......dization was used previously to show simultaneous action of two genes in frogs and in zebrafish by painting...nes at the same time." The three genes whose action was illuminated by Mauch's method are active in the mesoderm, the middle of three layers in an embry...Aquatic scientists divided on role of sea lice from salmon farms in decline of native salmon in B.C.
...lice treatments. Morton insists that if regulatory action is delayed, the consequences to wild fish could be serious. "The Norwegian scientists have said to me that they expected this problem to arise on the Pacific coast and that we will have good years for sea lice and bad years, but in the end we will lo...JCI table of contents, March 1 2004
... examined the effect of a high-fat diet on insulin action in mice lacking FATP1. In the March 1 issue of the Journal of Clinical Investigation the authors report that mice lacking FATP1 that were fed a regular chow diet experienced no changes in whole-body adiposity or insulin sensitivity. FATP1-knockout mi...U Iowa study identifies damaging mechanism in transplants and heart attacks
... anatomy and cell biology, found that blocking the action of this protein can prevent the tissue damage caused by ischemia/reperfusion injury. The study is published in the March 1 issue of the Journal of Clinical Investigation . Ischemia/reperfusion injury is a common, damaging component of organ transpla...New 'Understanding Evolution' Web site provides one-stop-shop for nation's science teachers
...ative Biology. "We see and read about evolution in action all the time, but we don't often think about it." The site is replete with practical examples of how evolution impacts our daily lives, including lesson plans about bunny breeding, the problem of antibiotic resistance in disease organisms, and the co...First ever legal challenge filed against the patenting of an animal
...tent on live beagle dogs was challenged in a legal action filed today by two non-profit organizations seeking to rescind the patent. The American Anti-Vivisection Society (AAVS) and the PatentWatch Project filed the legal challenge with the U.S. Patent and Trademark Office. In the challenge, the groups urge...New study seeks to establish mechanism between areas of the brain and continence
... necessary, the body has the ability to defer that action until an appropriate time. A new research study examines this issue and the findings could have beneficial implications for those patients with fecal incontinence resulting from a cerebrovascular accident and injuries to the frontal lobe. Backgroun...