Capturing cell protein production in action could help fight antibiotic resistance
...turing the protein-making factory, or ribosome, in action using cryo-electron microscopy will help scientist...g their ribosome machinery. Observing ribosomes in action helps us understand which areas of the protein complex evolve such resistance quickly. This informat...USC researchers produce a hairier mouse
...ssed in the skin. (Noggin works by suppressing the action of a protein called bone morphogenic protein, or BMP, which has a key role in a number of developmental pathways in mice and humans alike.) Because of the role that noggin appears to play in the development of integument (skin and associated feature...Microbial fuel cell cleans, generates electricity from domestic wastewater
...ment plant. Microbial fuel cells work through the action of bacteria which can pass electrons to an anode, the negative electrode of a fuel cell. The electrons flow from the anode through a wire, producing a current, to a cathode, the positive electrode of a fuel cell, where they combine with hydrogen ion...Protein abundant in human tumors confers resistance to anticancer drugs
...owever, the details of the biology underlying drug action and why some cancers are drug resistant are not well understood. A research team led by Dr. Donald Kufe from the Dana-Farber Cancer Institute in Boston, Massachusetts examined the role of a protein called MUC1 in drug resistance in cancer cells. The ...Experimental Biology 2004 - Translating the Genome
...covering how dopamine and other transmitters exert action on the nervous system. A special session honors the late Arthur C. Guyton, a legendary figure in cardiovascular physiology. American Society for Investigative Pathology (ASIP) offers sessions on topics including lung injury and repair, free radicals...Schering-Plough scientists identify protein essential for cholesterol absorption from intestine
...ay for cholesterol absorption and the mechanism of action for ZETIA TM (ezetimibe), scientists at Schering-Plough Research Institute (SPRI) have identified and characterized a long sought protein critical to intestinal cholesterol absorption. In an article published in the Feb. 20 issue of the journal Sc...Save The Tiger Fund announces alliance with the Critical Ecosystem Partnership Fund
...forts of many conservation organizations. Unified action is critical in addressing today's threats to tigers, which include highly organized regional networks that are smuggling tiger parts and are often linked to trafficking in narcotics and weapons. "Although terrorist threats, the economy and diseases ...Key advance reported in regenerating nerve fibers
...e developed techniques that disable the inhibitory action of myelin proteins, but this approach by itself ha...nerve cells that effectively removed the "braking" action of the myelin proteins spurring production of a molecule that sopped these inhibitory proteins up b...JCI table of contents, 16 February 2004
...********************************************* HDL action on cardiovascular health: is the answer NO? Circu...to consider therapeutic manipulation of direct HDL action on the endothelium to optimize cardiovascular health." TITLE: HDL induces NO-dependent vasorelaxatio...Flies offer clues to anesthesia-resistant memory
...lled arachidonic acid (AA). While the mechanism of action of AA in stabilizing memory still is unknown, this molecule has already been implicated in memory formation in chickens and rodents. The current genetic findings from flies therefore suggest that the radish/phospholipase A2-dependent form of memory s...Approved drug blocks deadly anthrax toxin
...for treatment of chronic hepatitis B can block the action of an anthrax toxin. In the online edition of the Proceedings of the National Academy of Sciences , a team led by Wei-Jen Tang of the University of Chicago shows that in vitro adefovir dipivoxil (sold as Hepsera) can effectively reduce the effects o...Duke open-air experiment results could deflate hopes that forests can alleviate global warming
...solution by CO2-produced carbonic acid. While that action would also remove carbon dioxide from the atmosphere and "store" the remnants in the added soil, the impact would be "trivial" compared to expectations from boosted tree growth, Schlesinger said. Based on available evidence from the Duke experiment, ...Optically recording millisecond brain nerve impulses
...produces three-dimensional images or movies. Each action potential is a single nerve impulse, traveling thr...e first multiphoton technique capable of detecting action potentials. SHG is particularly useful for imaging these impulses because it picks out only the cell...Digging for truth in Guatemala
...Program honors one or more scientists who, through action and example, have promoted human rights, usually at great personal cost. In 2004, the Program honors the members of the Guatemalan Forensic Anthropology Foundation (Fundacin de Antropologa Forense de Guatemala, FAFG). The FAFG investigates mass human...AAAS survey: 80 percent of adults say we're hurting oceans
... asking questions ranging from the need for global action on ocean pollution to human impacts on coastal ecosystems. Although only 31 percent of all survey respondents said they feel their actions could actually affect the health of the oceans, the survey also showed that Americans are nevertheless willing ...Computer scientists develop tool for mining genomic data
...treated with a certain drug, 116 genes spring into action while another 255 get shut off. But this state-of-the-art DNA microarray technology provides only a single snapshot of the cell. ''It's a very partial view,'' Koller says. What scientists really want to know is how groups of genes work together to co...Lake restrictions make lakeshore property more valuable
...ironmental economist at UW-Madison. "They can take action collectively, such as by forming associations that govern lake use, or they can take action privately by moving off the lake." In 1999, residents in Vilas County decided to take collective act...RNA inner workings partly unveiled in Stanford study
... center. The researchers speculate that the poking action may help slow down the transcription process so that the strands of DNA and newly made RNA can separate properly. "This turned out to be quite interesting. No one had even speculated about it before," said David Bushnell, PhD, a research associate a...Steroid-coated DNA represents new approach to gene delivery
... of inflammatory immune responses that reduces the action of the therapeutic gene. DNA is a large and negatively charged molecule, which is the source of the stumbling point in getting cells to take up DNA. To counter the negative charge of DNA, Diamond and his colleagues took a common steroid, dexametha...UT Southwestern researchers find leptin turns fat-storing cells into fat-burning cells
...oring to fat-burning to a massive increase in the action of mitochondria, the principal energy source of the cell. The increase in mitochondria, which also led to substantial weight loss in the rats, was found two weeks after researchers injected the leptin gene. Findings from the study will appear in an u...