Tag: "activation" at biology news

Dyslexics not doomed to life of reading difficulties

...he post-intervention imaging showed improved brain activation in areas associated with the meaning form as well ...tion in the meaning form exhibited increased brain activation in the sound form in addition to the meaning form. "Genes and neurons constrain learning, but instru...

Special training may help people with autism recognize faces

...ly and by age 12 normally developing children show activation in the fusiform gyrus when viewing faces. "People with autism tend to activate object-related brain regions when they are viewing unfamiliar faces. They also tend to focus on particular features, such as a mustache or a pair of glasses. Normal indi...

Immune system's attack dogs kept on genetic leash

...s activated, possibly triggering the inappropriate activation of immune cells." Peng speculates that other Fox ...evelopment of regulatory T cells that suppress the activation of other immune cells. But that's an external limit on cell activation. Foxj1 is the first gene to l...

Human embryonic stem cells may promise medical advances

...lapsed between the transfer of the nucleus and the activation of the newly transplanted genetic material, the team was able to optimize their results: A two-hour delay seemed to work best, so that 20 percent of all reconstructed eggs formed blastocysts. From the inner cell mass of these blastocysts, a single hu...

MIT team discovers memory mechanism

...hesis machinery helps explain the observation that activation of MAPK enhanced the production of a broad range of neuronal proteins. "Many people had thought that long-term memory formation involved only boosting the synthesis of a very limited set of proteins," said Tonegawa. "But to our surprise, this proces...

Natural killer cellers are made, not born

...bone marrow. There, the natural killer cells await activation (probably after stimulation by sentinel dendritic ...Service, is one of them. "The emerging data on the activation of natural killer cells, their distinct functions in the body and their cellular targets, are helpin...

Examining cardiac performance of tunas at the cellular level

...r temperature sensitivities and similar values for activation energy; and Western blots revealed that increased SERCA2 protein content is associated with the higher Ca2+ uptake and ATPase activities seen in bluefin ventricles compared to albacore, yellowfin and mackerel. Conclusions This study reveals that...

JCI table of contents, February 2, 2004

...n autoaggressive immune response. Why these T cell activation pathways differ between normal and T1DM patients w...lizing thrombus formation after vessel injury The activation of platelets contributes to the formation of thrombi in the circulation, which block arteries and ca...

Activation of receptor ups development of precancerous intestinal polyps

... researchers have provided the first evidence that activation of a particular cellular receptor dramatically inc...ategy for preventing colorectal cancer by blocking activation of this receptor. However, they also raise caution about an increased risk of colorectal c...

Monkey talk, human speech share left-brain processing

... scrambled monkey calls, etc. Instead, significant activation was seen in a different temporal lobe area on the ...ished. Conspicuously, no significant difference in activation was seen in the two temporal poles when the animals heard monkey calls. This suggests that monkey ...

New research technique provides clues into cell growth

...teins. In accordance with this synergistic effect, activation with only one of these proteins resulted in only a...t and increase in yellow light, while simultaneous activation with both resulted in a much more dramatic effect. "It was exciting to discover that we could not on...

JCI Table of Contents, January 15 2004

...pathway is likely to be involved in the persistent activation of the genes encoding proteins such as collagen, w...loop whereby an inhibitory molecule, Smad7, blocks activation of this pathway and promotes degradation of the TGF-beta receptor complex. Comparisons between norma...

Researchers unlock key secrets showing how tumors hide from immune system

...ells." The researchers documented that the tumor's activation of Stat3 (from the STAT family of proteins that re...nses by keeping dendritic cells from maturing. The activation also blocks expression of inflammatory mediators required to trigger the immune system. Other ongoi...

Research reveals brain has biological mechanism to block unwanted memories

...ng unwanted memories was associated with increased activation of the left and right frontal cortex (the part of ...d to repress memory), which in turn led to reduced activation of the hippocampus (the part of the brain used to remember experiences). In addition, the researcher...

Winter weather turns on flowering gene

...f the flower-suppressing genes. Specifically, VIN3 activation permanently modifies the structure of histones, a group of proteins over which DNA is wrapped. These changes block the flower-suppressing gene, switching the plant from a fixed state where it won't flower to a fixed state where it can flower. Scient...

Feeder-free system for maintaining pluripotency in embryonic stem cells pioneered

...s active. Chemical inhibition of GSK-3 thus mimics activation of Wnt and this keeps HESCs in an active, undiffer... that the synthetic compound was able to mimic Wnt activation in the classical model of frog early embryonic development. In the process, Brivanlou also discovere...

JCI table of contents, January 2, 2004

...*************************************** Caspase-3 activation triggers muscle breakdown Loss of muscle mass is ...ts that therapeutic strategies targeting caspase-3 activation may prevent muscle breakdown. TITLE: Activation of caspase-3 is an initial step triggering accelerat...

MIT helps unlock life-extending secrets of calorie restriction

... span. "These findings provide a simple model for activation of Sir2 and extension of life span by calorie restriction," the authors write. "Our findings suggest that the NAD/NADH ratio can serve a critical regulatory function, determining the life span of yeast mother cells. A reduction in this nucleotide act...

New understanding of why brain cells die after stroke will lead to development of new treatments

...pportunity to develop new medications that prevent activation of the TRPM7 channel. It will take approximately three years to develop a medication. "This is a quantum leap forward in understanding how stroke causes brain damage," says Dr. Michael Tymianski, neurosurgeon...

JCI table of contents, December 15 2003

...l mediator of this autoregulatory response through activation of P2X1 receptors. TITLE: Physiological rol...nk type 2 diabetes." TITLE: Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction AUTHOR CONTACT: Bradford B. L...

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