Tag: "acts" at biology news

Heat kills inoperable liver tumors without initiating onslaught of harmful hormones

..."Through this antenna we deliver radio energy that acts to kill the tumor cells by heating them up so hot that proteins are destroyed, similar to how an egg white is coagulated during a cooking procedure," Schell said. "So as a result, these tumor cells are basically cooked to death." To date, UF surg...

Like grapefruit, sour oranges boost drug effectiveness, scientists find, and also why

... disappears, and so more of a drug is absorbed and acts in the body," he said. In the new study, the research team had 10 healthy volunteers drink grapefruit juice, common orange juice or a sweetened form of Seville orange juice after receiving a single oral dose of felodipine, a drug to lower blood p...

Health websites can be unhealthy

...can say anything. There is no governing body that acts as a gatekeeper of Web pages, and we found that a lot of health information out there is inaccurate and just not true." There are more than 43 million web sites, Dorman says, and at least 10,000 of those post health information. One big problem deal...

Scientists detail parts of biological motor' key to cell life

... Every cell contains an assembly of proteins that acts like a motor on a one-way train: it quickly and efficiently moves materials such as chromosomes from the edge of the cell to the center. This protein motor, called dynein, is believed to be made up of 12 specialized parts, said Elisar Barbar of Ohio ...

ER stress in inflammatory bowel disease

...iP and of the protective MAP kinase pathway, which acts in both the unfolded protein response in the ER and in similar cytoplasmic pathways, as expected if the absence of Ire1b is required for homeostasis in response to increased levels of unfolded proteins in the secretory pathway. Evidently, Ire1a and ...

Violence and aggression: University of New Orleans researchers offer provocative insights

...ve group (about two-thirds of the childhood group) acts without thinking," Frick explains. "They feel bad about what they are doing, but they have trouble controlling their impulses. The other one-third, however, consists of individuals I call callous/unemotional (CU). They don't feel bad about their beha...

New technique answers one of waters basic mysteries

... the University of Rochester. "Its as if the water acts as both the splitter and the splitee at the same time." The research team found that the brief reaction happens when, by pure chance, a number of molecules of water surround another in a specific formation. That formation creates a quick electrical f...

Purdue researchers develop new delivery system for gene therapy

...s cell types associated with its protein coat, but acts like a retrovirus once inside the cell. "This allows us to expand the types of cells that can be treated with genetic therapy, because we get a virus that can infect those cells that the alphavirus would infect rather than the ones that the native re...

MGH researchers shed new light on how pain killers work

... are starting to understand how local inflammation acts centrally, we need to go down a parallel track and...molecule called interleukin 1 beta (IL-1b). IL-1b acts as the trigger that signals nerve cells to switch on the Cox-2 gene. This expression of Cox-2 in tu...

Mice nibbling at the secrets of NF1

...sor that negatively regulates the Ras protein. Ras acts as an intermediate between growth factor receptors on the outside of cells and the enzymatic cascade inside that activates genes required for cell proliferation and growth. NF1 is an essential checkpoint of Ras activity. Previous attempts to create a...

In possible boon to sickle cell victims, basic scientists find reason cells stick

...sing the crises if the circulating thromobospondin acts like a glue. Blood vessel walls damaged by the illness might boost clogging as the two proteins interact more readily because of the damage. "The next step will be to test our results in a mouse model of sickle cell disease and evaluate potential ...

With an eye on safety, UF experts explore cellular mechanisms of gene therapy

...tie up" the ends of the recombinant AAV so that it acts as if it were a tiny independent chromosome within the cell's nucleus, Flotte said. The protein - DNA-dependent protein kinase - is abundant in human cells. "That puts it into a relatively safe form in which the therapy can work but where it's not l...

Scientists unlock molecular mechanism that controls cell growth

...ulated by a heat-shock protein called Hsp70, which acts as a stress sensor. The protein an ancient protein found in nearly every organism on Earth patrols the cells immediate environment, in its role as constant protector. When biochemical stress builds to an unhealthy level, Hsp70 expression is rapidly...

Hopkins' Young Investigators' Day winners shine in the spotlight

... receptor in a cell's cytoplasm, called PEX5, that acts as a sort of card reader for enzymes and other proteins, recognizing them and leading them to peroxisomes where they do their work. Gatto's study, published in last December's Nature Structural Biology, takes a key step in explaining how human perox...

Measuring the muscle: new study by Scripps researchers depicts how the tuna's body is built for speed

... concentrated, back to the tail, which essentially acts as a natural, thrust-producing hydrofoil. Now, t...a more streamlined body and the motion at the tail acts almost like a propeller." Shadwick says the results of the study hold implications for research in...

Effects of iron-deficiency anemia in infants linger

...d for normal myelination. The myelin sheath, which acts like the casing of a sausage around the nerve, allows for more speedy transmission of signals from the brain to the rest of the body or from the periphery back to the brain. Without myelin, signals cannot be transmitted as efficiently. Much myelin fo...

Smart polymers provide size-selective switches to turn proteins on, off

...environmental change triggers an abrupt shift. It acts like a switch. Those factors could allow scientists, for example, to specifically target what they want to cull from a solution such as a blood sample. The proteins could be engineered to pull a specific molecule from the sample and hold it until t...

Trapping metalloproteinases in a serpins coils

...en uncertain. Herman et al. show here that TFPI-2 acts instead on a distinct class of targets, the matrix metalloproteinases, which are required to degrade collagen and other ECM components that are typically not the targets of serine proteinases. This biochemical activity is independent of TFPI-2s acti...

Soil fertility limits forests capacity to absorb excess CO2.

... nutrients," said Ellsworth. "While CO2 initially acts as a stimulus to the tree's physiology, our experiments suggest that short-term increases in growth are not sustainable over the long-term in low-nutrient environments." The open-air field study described in Nature is the first of its kind to exami...

Study finds wind, currents play key role where young fish settle

... slurped through the passes in pulses. The estuary acts as a big pump, taking water from close to shore, expelling it through the pass in a jet and then sucking the water back into the inlet, he said. Brown said this information could help fishery managers better identify essential fish habitats that are ...

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