Tag: "acute" at biology news

New study indicates arsenic could be suitable as first-line treatment in type of leukaemia

...tients who have relapsed after initial therapy for acute promyeloctytic leukaemia (APL). But now, a researc...e trial have died. APL accounts for around 10% of acute myeloid leukaemias and affects an estimated 20,000 people worldwide each year. It is a cancer of the...

UCSF scientist Joe Derisi named MaCarthur Fellow

...rstanding such infectious diseases as SARS (severe acute respiratory syndrome) and malaria. He is an associate professor of biochemistry and biophysics and Gordon M. Tomkins Chair at UCSF. The honor, which includes $500,000 in support over the next five years, to be used at the recipient's discretion, i...

UCI scientists successfully target key HIV protein; breakthrough may lead to new drug therapies

...ble to infections and certain cancers. Symptoms of acute HIV infection may include fever, headache, fatigue and enlarged lymph nodes. The virus is spread most commonly by having unprotected sex with an infected person. Funded by the Arnold and Mabel Beckman Foundation, the Burroughs Wellcome Fund and the N...

Keep genome data freely accessible

...ials, pointed to the recent experience with severe acute respiratory syndrome (SARS) as an example of the power of an open system. In March, 2003, WHO issued a global health alert about an atypical pneumonia in Vietnam, Hong Kong, and Guangdong Province in China. Within 6 weeks, the SARS coronavirus had be...

Experimental drug shown to block mutant protein causing blood disease

... in MPD damages organs and generally turns into an acute leukemia that can be fatal. The report appears in ...he underwent a bone-marrow transplant to treat the acute leukemia caused by her MPD. PKC412 acts similarly to the pioneering drug Gleevec, one of the first d...

Genetically modified bacterium as remedy for intestinal diseases

...is was also demonstrated in the tests on mice with acute enteritis: oral administration of TFF had no effec...fers promising prospects for the treatment of both acute and chronic intestinal inflammation, and it can potentially be extended to other therapeutics as wel...

New research suggests link between maternal diet and childhood leukemia risk

...ared 138 women who each had a child diagnosed with acute lymphoblastic leukemia (ALL) with a control group of 138 women whose children did not have cancer. The children of all the women in the study were matched by sex, age, race, and county of residence at birth. After comparing the women's diets in the...

Long-term effects of carbon monoxide poisoning are an autoimmune reaction

... the study along those lines," says Thom. To link acute CO poisoning to long-term brain injury, the team conducted tests on normal versus CO-poisoned rats, comparing their abilities to navigate and memorize a maze. "CO poisoned rats don't learn," said Thom. "But if you render their immune systems tolera...

New model can aid in understanding immune system diseases

...miological studies show a correlative link between acute Epstein-Barr virus and autoimmune diseases, particularly lupus and arthritis," Bishop said. "We're wondering, 'Where does this link come from?' If the viral protein causes B cells to be hyperactive, this might increase the propensity of the small num...

Leukemia stem cells identified by Stanford researchers

... Other researchers have found cancer stem cells in acute myelogenous leukemia, breast cancer and two types of brain cancer. The current work, published in the Aug. 12 New England Journal of Medicine , is the first to describe these cells in chronic myelogenous leukemia. This is also the first time researc...

Outcome for acute lymphoblastic leukemia linked to gene expression patterns

...nsitivity to four major cancer drugs used to treat acute lymphoblastic leukemia (ALL), suggesting that these genes are key to treatment outcome. This study, by investigators from St. Jude Children's Research Hospital and Erasmus University Medical Center/Sophia Children's Hospital, Rotterdam, The Netherlan...

Commercialization deal boosts hope for new sickle-cell drug

...ly to tissues. Consequently, patients suffer from acute painful crises and numerous health problems, such as acute chest syndrome and organ damage, resulting in a shortened lifespan. Dr. Brugnara and colleag...

New view of leukemia cells identifies best treatment options, Stanford researchers say

STANFORD, Calif. - People diagnosed with acute myelogenous leukemia usually receive the most commonly effective chemotherapy as a first line of attack, but it doesn't work for everyone. Faced with these resistant cancers, doctors move on to the next most effective treatment or perhaps a drug stil...

It's a no-brainer: Prepare for West Nile virus

...ss and in those who are critically ill to rule out acute flaccid paralysis syndrome, a severe neuromuscular complication of the disease which may lead to prolonged disability or death....

Why some neonates need caffeine

... of pure O2 . This drop in ventilation involves an acute reduction in peripheral chemoreceptor inputs (i.e., physiological chemodenervation) and thus reflects the strength of the peripheral chemoreceptor drive. The decrease is ultimately followed by an increase in ventilation that is centrally mediated. Ho...

Long-term heart damage may result from constant confrontation and defeat

...time. There is a general tendency to consider the acute effects observed during and shortly after either a...tudy takes a different approach, analyzing whether acute and long-term sympathovagal responsivity to intermittent defeat episodes are affected by a chronic p...

Acamprosate: potential medication for treating alcoholism

...rmacokinetics (the way it moves through the body), acute physiological or psychomotor alcohol effects, or most subjective alcohol effects. "While the results of this study are rather clear and straightforward, namely, that acamprosate has minimal effects on the alcohol experience, the findings shou...

Gene profiles could improve acute leukemia diagnosis and lead to better treatments

...alysis of genes from both children and adults with acute myeloid leukemia (AML) could significantly improve the ability to make accurate diagnoses and prognoses for the major genetic (molecular) subtypes of the pediatric form of this disease and lead to better treatments. This finding, by investigators at ...

Scientists discover key step in the development of nerve cells controlling autonomic functions

...nt target of chromosomal translocations that cause acute myeloid leukemia. "This is a significant finding as it suggests for the first time that similar mechanisms involving Runx1 play roles in motor nerve cell and blood cell development and importantly it provides a new avenue of research into the mechan...

New pulmonary hypertension guideline challenges use of common medication

...ers or their use in patients who do not respond to acute pulmonary vasodilator testing, citing an increased risk of adverse and potentially fatal events related to the use of the medication. Due to the severity of the disease, the panel also advises genetic testing for patients with a family history of PA...

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